Zobrazeno 1 - 10
of 2 606
pro vyhledávání: '"GSK3B"'
Autor:
Koji Ueno, Hiroshi Kurazumi, Ryo Suzuki, Masashi Yanagihara, Takahiro Mizoguchi, Takasuke Harada, Noriyasu Morikage, Kimikazu Hamano
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The aim of this study was to identify angiogenic microRNAs (miRNAs) that could be used in the treatment of hindlimb ischemic tissues. miRNAs contained in extracellular vesicles (EVs) deriving from the plasma were analyzed in C57BL/6 mice, wh
Externí odkaz:
https://doaj.org/article/cd2ff9b54ce34dc9aaff4cb831f0b620
Publikováno v:
Journal of Pharmacy and Bioallied Sciences, Vol 16, Iss 6, Pp 1291-1294 (2024)
Diabetes mellitus is a persistent metabolic condition marked by elevated blood glucose levels due to compromised insulin secretion or functionality. The search for natural antidiabetic agents has gained attention due to their potential effectiveness
Externí odkaz:
https://doaj.org/article/14d348c31bfe4b65b47c8bc5f25a0a2c
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-20 (2024)
Abstract Objective Anesthetics have been linked to cognitive alterations, particularly in the elderly. The current research delineates how Fibroblast Growth Factor 2 (Fgf2) modulates tau protein phosphorylation, contributing to cognitive impairments
Externí odkaz:
https://doaj.org/article/b7ace567b7844f73b007bd84a544d32e
Publikováno v:
Physiological Reports, Vol 12, Iss 16, Pp n/a-n/a (2024)
Abstract Brain‐derived neurotrophic factor (BDNF) content and signaling has been identified as one potential regulator of amyloid precursor protein (APP) processing. Recently published work has demonstrated that BDNF reduces BACE1 activity while al
Externí odkaz:
https://doaj.org/article/6edfb64a5ed148abad304f9baaa981df
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-15 (2024)
Abstract Iron metabolism disorders are implicated in the pathogenesis of Alzheimer’s disease (AD). It was previously reported that transferrin receptor (TFR1) expression was upregulated in AD mouse model. However, the precise biological functions o
Externí odkaz:
https://doaj.org/article/ec2c35f51c3a4c13bdcd9f61ee563303
Autor:
Hung-Pei Tsai, Chien-Ju Lin, Ann-Shung Lieu, Yi-Ting Chen, Tzu-Ting Tseng, Aij-Lie Kwan, Joon-Khim Loh
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 4, Pp 3591-3602 (2023)
Numerous studies have considered galectin-3 or Glycogen synthase kinase 3 beta (GSK3B) as a potential prognosis marker for various cancers. However, the correlation between the protein expression of galectin-3/GSK3B and the clinical parameters of ast
Externí odkaz:
https://doaj.org/article/056b414379b0441f8c8b6515225e1a9b
Publikováno v:
Journal of Medical Biochemistry, Vol 42, Iss 1, Pp 105-112 (2023)
Background: We intended to investigate the role and regulatory mechanism of EPS8L3 in increase the development of pancreatic cancer (PC). Methods: In order to analyze the relationship between EPS8L3 level and clinicopathological indicators of PC pati
Externí odkaz:
https://doaj.org/article/aaf7a64e8cd740ba910dc820c758a1f0
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Autor:
Gi Young Seo, Elliott S. Neal, Felicity Han, Diana Vidovic, Fathima Nooru‐Mohamed, Gerald A. Dienel, Mitchell A. Sullivan, Karin Borges
Publikováno v:
Epilepsia Open, Vol 7, Iss 2, Pp 361-367 (2022)
Abstract Glucose is the main brain fuel in fed conditions, while astrocytic glycogen is used as supplemental fuel when the brain is stimulated. Brain glycogen levels are decreased shortly after induced seizures in rodents, but little is known about h
Externí odkaz:
https://doaj.org/article/7cd18561508545f2831d11923c820af3
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 38, Iss 4, Pp 347-356 (2022)
Abstract Allergic rhinitis (AR) is a chronic inflammatory disease of the nasal mucosa. M2 macrophage polarization can reduce inflammation and repair tissue injury during AR development. Studies have substantiated the involvement of miRNAs in AR patho
Externí odkaz:
https://doaj.org/article/2ab20c0465624420b11063368cacecb8