Zobrazeno 1 - 10
of 11
pro vyhledávání: '"GSK3β, Glycogen synthase kinase 3 beta"'
Autor:
Heidi L. Weiss, Stephanie A. Rock, Tianyan Gao, Chi Wang, Jing Li, B. Mark Evers, Yuanyuan Wu, Kai Jiang, Yajuan Liu, Jianhang Jia
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 2, Pp 501-516 (2022)
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 2, Pp 501-516 (2022)
Background & Aims: Intestinal stem cells (ISCs) are sensitive to dietary alterations and nutrient availability. Neurotensin (NT), a gut peptide localized predominantly to the small bowel and released by fat ingestion, stimulates the growth of intesti
Autor:
Pingping Luo, Rui Zhang, Qian Yu, George L. Tipoe, Ming Zheng, Xiaoming Sun, Yingxia Liu, Jia Xiao, Wei Li, Hong Zhang
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 668-679 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 668-679 (2021)
Alcoholic liver disease (ALD) causes insulin resistance, lipid metabolism dysfunction, and inflammation. We investigated the protective effects and direct regulating target of S-allylmercaptocysteine (SAMC) from aged garlic on liver cell injury. A ch
Autor:
Anja Jaeschke, David Y. Hui, Anton J.M. Roebroek, April Haller, Christopher Nam, Emily Igel, James G. Cash
Publikováno v:
Journal of Lipid Research, Vol 62, Iss, Pp 100012-(2021)
Journal of Lipid Research
Journal of Lipid Research
The LDL receptor-related protein-1 (LRP1) is highly expressed in numerous cell types, and its impairment is associated with obesity, diabetes, and fatty liver disease. However, the mechanisms linking LRP1 to metabolic disease are not completely under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c290f4d72cef781f80ddd5245699b83
https://lirias.kuleuven.be/handle/20.500.12942/704812
https://lirias.kuleuven.be/handle/20.500.12942/704812
Autor:
Qin Wang, Namakkal S. Rajasekaran, Kishore Kumar S Narasimhan, Thomas van Groen, Sandhya Sundaram, Federica del Monte, Goutam Karan, Asokan Devarajan
Publikováno v:
Redox Biology
Redox Biology, Vol 37, Iss, Pp 101739-(2020)
Redox Biology, Vol 37, Iss, Pp 101739-(2020)
Redox homeostasis regulates key cellular signaling in both physiology and pathology. While perturbations result in shifting the redox homeostasis towards oxidative stress are well documented, the influence of reductive stress (RS) in neurodegenerativ
Publikováno v:
Pharmacological Research
Graphical abstract Molecular targets modulated by artemisinins in respiratory diseases.
Artemisinins are sesquiterpene lactones with a peroxide moiety that are isolated from the herb Artemisia annua. It has been used for centuries for the treatm
Artemisinins are sesquiterpene lactones with a peroxide moiety that are isolated from the herb Artemisia annua. It has been used for centuries for the treatm
Autor:
Paul, Debasish, Bargale, Anil Bapu, Rapole, Srikanth, Shetty, Praveen Kumar, Santra, Manas Kumar
Publikováno v:
Neoplasia (New York, N.Y.)
Protein phosphatases play a crucial role in cell cycle progression, cell survival, cellular signaling, and genomic integrity. The protein phosphatase 1 (PP1) regulatory subunit SDS22 plays a significant role in cell cycle progression. A recent study
Autor:
Qun Lu, Lei Ding, Yan-Hua Chen, Lesley Jasmine Benderman, Joel S. Parker, Tiaosi Xing, Stephiya Sabu, Jeffrey Yang
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 4, Pp 641-659 (2020)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Claudin-7 (Cldn7) is a tight junction (TJ) membrane protein located at the apical TJ and basolateral side of intestinal epithelial cells. Deletion of Cldn7 by gene targeting leads to the inflammatory bowel disease–like phenotype i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b09406cc28198905364c0398869c795e
Autor:
Shahbaz Katebzadeh, Zohra Tumur, Tursun Alkam, Lokesh Bhushan, Bradley S. Henson, Carlos Guerra
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 17, Iss 1, Pp 141-151 (2015)
Neoplasia: An International Journal for Oncology Research, Vol 17, Iss 1, Pp 141-151 (2015)
Epidermal growth factor receptor (EGFR) is overexpressed in head and neck squamous cell carcinoma (HNSCC) where it has been shown to promote tumor cell invasion upon phosphorylation. One mechanism by which EGFR promotes tumor progression is by activa
Autor:
Fan Z; Department of Pathogenic Biology, School of Medicine, Nantong University, Nantong 226001, China.; Laboratory of Medical Science, School of Medicine, Nantong University, Nantong 226001, China., Wu C; Laboratory of Medical Science, School of Medicine, Nantong University, Nantong 226001, China.; Department of Dermatology, Affiliated Hospital of Nantong University, Nantong University, Nantong 226001, China., Chen M; Laboratory of Medical Science, School of Medicine, Nantong University, Nantong 226001, China., Jiang Y; Department of Pathophysiology, School of Medicine, Nantong University, Nantong 226001, China., Wu Y; Laboratory of Medical Science, School of Medicine, Nantong University, Nantong 226001, China., Mao R; Department of Pathophysiology, School of Medicine, Nantong University, Nantong 226001, China., Fan Y; Department of Pathogenic Biology, School of Medicine, Nantong University, Nantong 226001, China.; Laboratory of Medical Science, School of Medicine, Nantong University, Nantong 226001, China.
Publikováno v:
Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2022 Mar; Vol. 12 (3), pp. 1041-1053. Date of Electronic Publication: 2021 Sep 16.
Autor:
Francesca F; School of Behavioural and Health Sciences, Faculty of Health Sciences, Australian Catholic University, 1100 Nudgee Rd, Banyo, Queensland, 4014, Australia.; Centre for Genomics and Personalised Medicine, Genomics Research Centre, Queensland University of Technology, 60 Musk Avenue, Kelvin Grove, QLD, 4059, Australia., Caitlin A; School of Behavioural and Health Sciences, Faculty of Health Sciences, Australian Catholic University, 1100 Nudgee Rd, Banyo, Queensland, 4014, Australia.; Centre for Genomics and Personalised Medicine, Genomics Research Centre, Queensland University of Technology, 60 Musk Avenue, Kelvin Grove, QLD, 4059, Australia., Sarah L; School of Behavioural and Health Sciences, Faculty of Health Sciences, Australian Catholic University, 1100 Nudgee Rd, Banyo, Queensland, 4014, Australia.; Centre for Genomics and Personalised Medicine, Genomics Research Centre, Queensland University of Technology, 60 Musk Avenue, Kelvin Grove, QLD, 4059, Australia., Robyn GL; Centre for Genomics and Personalised Medicine, Genomics Research Centre, Queensland University of Technology, 60 Musk Avenue, Kelvin Grove, QLD, 4059, Australia.
Publikováno v:
Brain, behavior, & immunity - health [Brain Behav Immun Health] 2022 Feb 24; Vol. 21, pp. 100435. Date of Electronic Publication: 2022 Feb 24 (Print Publication: 2022).