Zobrazeno 1 - 10
of 103
pro vyhledávání: '"GSK 3β"'
Publikováno v:
Journal of Ginseng Research, Vol 46, Iss 5, Pp 666-674 (2022)
Background: Ginsenosides and their metabolites have antidepressant-like effects, but the underlying mechanisms remain unclear. We previously identified 14-3-3 ζ as one of the target proteins of 20 (S)-protopanaxadiol (PPD), a fully deglycosylated gi
Externí odkaz:
https://doaj.org/article/88fe4e92d082479c95d6c55db4a02025
Publikováno v:
Life, Vol 13, Iss 11, p 2234 (2023)
GSK3β is a promising target for treating various disease conditions, including myocardial ischemia–reperfusion injury (IR). This study investigated the potential of GSK3β as a novel drug for managing IR in rats exposed to PM2.5 for 1 day and up t
Externí odkaz:
https://doaj.org/article/4552a27d02ad4145a75b886eeb588c26
Publikováno v:
Cells, Vol 12, Iss 16, p 2064 (2023)
Circulatory GSK3β is recognized as a biomarker and therapeutic target for diseases, including myocardial diseases. However, its potential as a target for myocardial ischemia-reperfusion injury (IR) in the presence of PM2.5 exposure is unclear. Wista
Externí odkaz:
https://doaj.org/article/2059703cc23740a78198a00dc2498161
Autor:
Xi-Yuan Liu, Rui Lu, Jing Chen, Jie Wang, Hong-Mei Qian, Gang Chen, Rong-Han Wu, Zai-Long Chi
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Retinal pigment epithelium (RPE) serves critical functions in maintaining retinal homeostasis. An important function of RPE is to degrade the photoreceptor outer segment fragments daily to maintain photoreceptor function and longevity throughout life
Externí odkaz:
https://doaj.org/article/14b84c31c08247c19efd035be8e087bf
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-11 (2018)
Abstract Background Wnt signaling has been linked with P-glycoprotein (P-gp) overexpression and which was mainly mediated by β-catenin nuclear translocation. Flavonoids have already been reported as modulators of the Wnt/β-catenin pathway and hence
Externí odkaz:
https://doaj.org/article/71753bd307b24a10a64a76d0b72b5a19
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Autor:
Robert A. Mans, Kyle D. Hinton, Cicely H. Payne, Grace E. Powers, Nicole L. Scheuermann, Michael Saint-Jean
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
The sequencing of the zebrafish genome, the emergence of powerful gene-editing tools, and the development of in vivo imaging techniques have propelled the economical zebrafish into prominence as a biomedical research model. Neurodegenerative disorder
Externí odkaz:
https://doaj.org/article/16239449daa043739752bfbd5de85813
Autor:
Yilin Hou, Jiqian Zhao, Runkang Xuan, Dingding Yang, Wenting Wang, Shengxi Wu, Rou-Gang Xie, Xufeng Liu, Yazhou Wang, Huiming Mo, Mengmeng Wang, Lirong Liang
Publikováno v:
Biochemical and Biophysical Research Communications. 550:22-29
Autism spectrum disorders (ASD) are a group of neurological disorders which affect approximately 1% of children around the world. Social dysfunction is one of the two core syndromes of ASD, and still lacks effective treatment. Transcranial magnetic s
Akademický článek
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