P01.07 Galectin 9 dependent immune evasion machinery as a potential target for personalised immunotherapy of cancer

Autor: VV Sumbayev, I Yasinska, S Schlichtner, GS Lall, E Fasler-Kan, BF Gibbs

Publikováno v: Poster Presentations.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0f380c00ade4f65851355ab3b0ee653b
https://doi.org/10.1136/jitc-2022-itoc9.19

L-Kynurenine participates in cancer immune evasion by downregulating hypoxic signaling in T lymphocytes.

Autor: Schlichtner S; Medway School of Pharmacy, Universities of Kent and Greenwich, Chatham Maritime, UK.; Department of Personalized Medical Oncology, DKFZ-Hector Cancer Institute at the University Medical Center Mannheim, Mannheim, Germany.; Division of Personalized Medical Oncology (A420), German Cancer Research Center (DKFZ); German Center for Lung Research (DZL), Heidelberg, Germany.; Department of Personalized Oncology, University Hospital Mannheim, Mannheim, Germany., Yasinska IM; Medway School of Pharmacy, Universities of Kent and Greenwich, Chatham Maritime, UK., Klenova E; School of Biological Sciences, University of Essex, Colchester, UK., Abooali M; Medway School of Pharmacy, Universities of Kent and Greenwich, Chatham Maritime, UK., Lall GS; Medway School of Pharmacy, Universities of Kent and Greenwich, Chatham Maritime, UK., Berger SM; Department of Pediatric Surgery, Children's Hospital, Inselspital Bern, University of Bern and Department of Biomedical Research, University of Bern, Bern, Switzerland., Ruggiero S; Department of Pediatric Surgery, Children's Hospital, Inselspital Bern, University of Bern and Department of Biomedical Research, University of Bern, Bern, Switzerland.; Department of Human Medicine, University of Oldenburg, Oldenburg, Germany., Cholewa D; Department of Pediatric Surgery, Children's Hospital, Inselspital Bern, University of Bern and Department of Biomedical Research, University of Bern, Bern, Switzerland., Milošević M; Department of Pediatric Surgery, Children's Hospital, Inselspital Bern, University of Bern and Department of Biomedical Research, University of Bern, Bern, Switzerland., Gibbs BF; Medway School of Pharmacy, Universities of Kent and Greenwich, Chatham Maritime, UK.; Department of Human Medicine, University of Oldenburg, Oldenburg, Germany., Fasler-Kan E; Department of Pediatric Surgery, Children's Hospital, Inselspital Bern, University of Bern and Department of Biomedical Research, University of Bern, Bern, Switzerland., Sumbayev VV; Medway School of Pharmacy, Universities of Kent and Greenwich, Chatham Maritime, UK.

Publikováno v: Oncoimmunology [Oncoimmunology] 2023 Aug 10; Vol. 12 (1), pp. 2244330. Date of Electronic Publication: 2023 Aug 10 (Print Publication: 2023).

TRESK is a key regulator of nocturnal suprachiasmatic nucleus dynamics and light adaptive responses.

Autor: Lalic T; Translational Molecular Neuroscience Group, Weatherall Institute of Molecular Medicine, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK. tatjana.lalic@ndcn.ox.ac.uk., Steponenaite A; Medway School of Pharmacy, University of Kent and University of Greenwich, Anson Building, Central Avenue, Chatham, Kent, ME4 4TB, UK., Wei L; Translational Molecular Neuroscience Group, Weatherall Institute of Molecular Medicine, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK., Vasudevan SR; Department of Pharmacology, University of Oxford, Oxford, OX1 3QT, UK., Mathie A; Medway School of Pharmacy, University of Kent and University of Greenwich, Anson Building, Central Avenue, Chatham, Kent, ME4 4TB, UK., Peirson SN; Sleep and Circadian Neuroscience Institute (SCNi), Nuffield Department of Clinical Neurosciences, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK., Lall GS; Medway School of Pharmacy, University of Kent and University of Greenwich, Anson Building, Central Avenue, Chatham, Kent, ME4 4TB, UK. G.Lall@kent.ac.uk., Cader MZ; Translational Molecular Neuroscience Group, Weatherall Institute of Molecular Medicine, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK. zameel.cader@ndcn.ox.ac.uk.

Publikováno v: Nature communications [Nat Commun] 2020 Sep 14; Vol. 11 (1), pp. 4614. Date of Electronic Publication: 2020 Sep 14.

Alterations in glutamatergic signaling contribute to the decline of circadian photoentrainment in aged mice.

Autor: Biello SM; Department of Psychology, University of Glasgow, Glasgow, UK., Bonsall DR; Medway School of Pharmacy, University of Kent, Chatham, UK; Neuroscience Program, Smith College, Northampton, MA, USA., Atkinson LA; Medway School of Pharmacy, University of Kent, Chatham, UK., Molyneux PC; Neuroscience Program, Smith College, Northampton, MA, USA., Harrington ME; Neuroscience Program, Smith College, Northampton, MA, USA., Lall GS; Medway School of Pharmacy, University of Kent, Chatham, UK. Electronic address: g.lall@kent.ac.uk.

Publikováno v: Neurobiology of aging [Neurobiol Aging] 2018 Jun; Vol. 66, pp. 75-84. Date of Electronic Publication: 2018 Feb 20.

The HIF-1 transcription complex is essential for translational control of myeloid hematopoietic cell function by maintaining mTOR phosphorylation.

Autor: Yasinska IM; Medway School of Pharmacy, University of Kent, Anson Building, Central Avenue, Chatham Maritime, Kent, ME4 4TB, UK., Gibbs BF, Lall GS, Sumbayev VV

Publikováno v: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2014 Feb; Vol. 71 (4), pp. 699-710. Date of Electronic Publication: 2013 Jul 20.