Zobrazeno 1 - 10
of 60
pro vyhledávání: '"GRV Hughes"'
Autor:
Grv Hughes
Publikováno v:
Lupus. 27(9)
Publikováno v:
Fetal and Maternal Medicine Review. 22:265-286
The Antiphospholipid syndrome (APS) is one of the current hot topics embracing rheumatology and obstetrics.The first clinical description of APS was in 1983. Venous or arterial thrombosis, abortion and cerebral manifestations along with circulating a
Autor:
Antonio Brucato, F. G. Garcia-Hernandez, Ricard Cervera, A. Ruffatti, Maria Tiziana Bertero, Munther A. Khamashta, Angela Tincani, M. Belmonte-Serrano, Grv Hughes, Andrea Doria, Gerard Espinosa, Julio Sánchez-Román, Cecilia N. Pisoni
Publikováno v:
Arthritis & Rheumatism. 62:1147-1152
Objective Congenital heart block (CHB) is presumed to be caused by transplacental passage of maternal immunoglobulin against Ro and La ribonucleoproteins. The recurrence rate in subsequent pregnancies following the birth of a child with CHB is ∼19%
Autor:
Miri Blank, Zdenka Ulcova-Gallova, P von Landenberg, J Font, Shaul Lev, Gyula Szegedi, Pierre Youinou, Andreas Jönsen, Pl Meroni, M.C Boffa, Blaž Rozman, Amelia Ruffatti, Sonja Praprotnik, Ilan Krause, Vittorio Pengo, Filip Kvapil, J.C. Piette, Grv Hughes, Y Shoenfeld, Gunnar Sturfelt, Marielle Sanmarco, Takao Koike, J Sulkes, J Zaech, VB Vriezman, Ricard Cervera, Munther A. Khamashta, Angela Tincani, M L Bertolaccini, José Delgado Alves, Gabriella Lakos, Margalit Lorber
Publikováno v:
Journal of Clinical Immunology. 23:377-383
Two-hundred ninety five patients with the antiphospholipid syndrome (APS) were studied for the presence of antibodies against six anti-beta2GPI-related peptides Abs. The prevalence of a wide spectrum of clinical and laboratory parameters of APS was e
Autor:
Kenneth B.M. Reid, Kedarnath N. Sastry, Munther A. Khamashta, Eugene G. Zappi, Grv Hughes, Uday Kishore, Richard D. Sontheimer, Paul Eggleton
Publikováno v:
Clinical and Experimental Immunology. 108:181-190
SUMMARY Following its release from cells during infection and inflammation, calreticulin (CRT) can act as an autoantigen in diseases such as SLE. Why CRT is a target of protective immunity and whether it may interfere with innate immunity once releas
Publikováno v:
Scopus-Elsevier
P. L. MERONI, D. D’CRUZ*, M. KHAMASHTAy, P. YOUINOUz & G. R. V. HUGHESy Istituto di Medicina Interna, Malattie Infettive & Immunopatologia, University of Milan, Milan, Italy, *Department of Rheumatology, St Bartholomew’s Hospital and yLupus Resea
Autor:
L.S. Atmaca, David D'Cruz, A. O. Aydintug, Grv Hughes, Munther A. Khamashta, Nurşen Düzgün, Ricard Cervera, Aysel Gürler, G. Tokgöz
Publikováno v:
Clinical Immunology and Immunopathology. 67:157-162
Autoantibodies that bind to endothelial cells have been identified in patients with several forms of vasculitis. Behçet's disease--a multisystem inflammatory disorder of unknown etiology--is associated with thrombosis in addition to systemic manifes
Autor:
Grv Hughes
Publikováno v:
Lupus. 22:759-760
A leader in The Times of London (28th November 2012) entitled ‘‘The Stillbirth Scandal’’ raged against the fact that (in the UK), ‘‘every day as many as three babies are stillborn who could have lived’’. A linked article in The Times
Autor:
Yehuda Shoenfeld, Eiji Matsuura, Kazuko Kobayashi, Grv Hughes, Munther A. Khamashta, Takao Koike
Publikováno v:
Lupus. 12(7)
Beta2-Glycoprotein I (beta2-GPI) is a major antigen for anticardiolipin antibodies (aCL, Abs) present in patients with antiphospholipid syndrome (APS). We recently reported that oxidized LDL(oxLDL) is subsequently targeted by beta2-GPI and anti-beta2
Autor:
F J Ward, Munther A. Khamashta, N A Staines, Elaine F. Corbett, Marek Michalak, Steven Johnson, Paul Eggleton, V A Hajela, Grv Hughes, Kenneth B.M. Reid
Publikováno v:
Clinical and experimental immunology. 120(2)
SUMMARYExtracellular calreticulin (CRT) as well as anti-CRT antibodies have been reported in patients with various autoimmune disorders and CRT has been implicated in ‘epitope spreading’ to other autoantigens such as the Ro/SS-A complex. In addit