The high affinity melatonin binding site probed with conformationally restricted ligands .1. Pharmacophore and minireceptor models

Autor: Jansen, JM, Copinga, S, Gruppen, G, Molinari, EJ, Dubocovich, ML, Grol, CJ

Publikováno v: Bioorganic & Medicinal Chemistry, 4(8), 1321-1332. PERGAMON-ELSEVIER SCIENCE LTD

The affinities of enantiomers of conformationally restricted melatonin analogues for the ML-1 and ML-2 putative melatonin receptor subtypes are reported. Most ligands exhibited reversed stereoselectivity when competing with I-125 2-iodomelatonin bind

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::778c6c6907aea2d2854a88ea91dd1ca4
https://research.rug.nl/en/publications/be3b34f3-0f76-4d07-97c5-edfaa57fd483

CONVERSION OF DIPEPTIDES AND A TETRAPEPTIDE TO MACROCYCLIC IONOPHORES BY MEANS OF CESIUM AIDED RING-CLOSURE OF THE N-2-CHLOROACETYL DERIVATIVES

Autor: KRUIZINGA, WH, KINGMA, R, LEEGSTRA, L, ROKASZEWSKI, E, GRUPPEN, G, KELLOGG, RM

Publikováno v: Journal of the Chemical Society-Chemical Communications, 1647-1648. ROYAL SOC CHEMISTRY
ISSUE=22;STARTPAGE=1647;ENDPAGE=1648;ISSN=0022-4936;TITLE=Journal of the Chemical Society-Chemical Communications

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::91ab8459f4942e22438c97a30eb104e0
https://research.rug.nl/en/publications/3750be71-07d5-45e8-b909-33ccdddfe9a6

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ChemInform Abstract: Conversion of Dipeptides and a Tetrapeptide to Macrocyclic Ionophores by Means of Cesium-Aided Ring Closure of the N-2-Chloroacetyl Derivatives.

Autor: KRUIZINGA, W. H., KINGMA, R., LEEGSTRA, L., ROKASZEWSKI, E., GRUPPEN, G., KELLOGG, R. M.

Publikováno v: ChemInform; Apr1991, Vol. 22 Issue 17, pno-no, 1p