Zobrazeno 1 - 10
of 692
pro vyhledávání: '"GRPR"'
Autor:
Andreas Rinscheid, Alexander Gäble, Georgine Wienand, Alexander Dierks, Malte Kircher, Thomas Günther, Marianne Patt, Ralph A. Bundschuh, Constantin Lapa, Christian H. Pfob
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Background In patients with prostate cancer (PCa), imaging with gastrin-releasing peptide receptor (GRPR) ligands is an alternative to PSMA-targeted tracers, particularly if PSMA expression is low or absent. [99mTc]Tc-N4-BTG is a newly devel
Externí odkaz:
https://doaj.org/article/3d0bd12cbdad420fa3f2ccc2d54f5657
Publikováno v:
iRADIOLOGY, Vol 2, Iss 2, Pp 128-155 (2024)
Abstract Optimal therapeutic and diagnostic efficacy is essential for healthcare's global mission of advancing oncologic drug development. Accurate diagnosis and detection are crucial prerequisites for effective risk stratification and personalized p
Externí odkaz:
https://doaj.org/article/581ec3af255d4077ac1263947fae3b69
Autor:
Panagiotis Kanellopoulos, Adam Mattsson, Ayman Abouzayed, Karim Obeid, Berthold A. Nock, Vladimir Tolmachev, Theodosia Maina, Anna Orlova
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-19 (2024)
Abstract Background The gastrin-releasing peptide receptor (GRPR) has been extensively studied as a biomolecular target for peptide-based radiotheranostics. However, the lack of metabolic stability and the rapid clearance of peptide radioligands, inc
Externí odkaz:
https://doaj.org/article/637e1155b147456f8a59fd7e94ba6862
Publikováno v:
Annals of Medicine, Vol 56, Iss 1 (2024)
AbstractAim: This comprehensive review aims to explore the potential applications of Gastrin-releasing peptide receptor (GRPR) in the diagnosis and treatment of prostate cancer. Additionally, the study investigates the role of GRPR in prognostic asse
Externí odkaz:
https://doaj.org/article/65af275c981f4ff3991a38bbf8f9cf4f
Autor:
Karim Obeid, Panagiotis Kanellopoulos, Ayman Abouzayed, Adam Mattsson, Vladimir Tolmachev, Berthold A. Nock, Theodosia Maina, Anna Orlova
Publikováno v:
Pharmaceutics, Vol 16, Iss 4, p 513 (2024)
Gastrin-releasing peptide receptor (GRPR)-antagonists have served as motifs in the development of theranostic radioligands for prostate cancer. Our efforts have been focused on the development of radiolabeled RM26 (H-DPhe6–Gln7–Trp8–Ala9–Val1
Externí odkaz:
https://doaj.org/article/76e700bb020b4623bb32b8e8e73fddd6
Akademický článek
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Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Background The gastrin-releasing peptide receptor (GRPr) is a molecular target for the visualization of prostate cancer. Bombesin (BN) analogs are short peptides with a high affinity for GRPr. RM2 is a bombesin-based antagonist. It has been
Externí odkaz:
https://doaj.org/article/f4a7dde5bbad410c90babea9ab961f7e
Autor:
Raphaëlle Quillet, Maria Gutierrez-Mecinas, Erika Polgár, Allen C. Dickie, Kieran A. Boyle, Masahiko Watanabe, Andrew J. Todd
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
The superficial dorsal horn (SDH) of the spinal cord contains a diverse array of neurons. The vast majority of these are interneurons, most of which are glutamatergic. These can be assigned to several populations, one of which is defined by expressio
Externí odkaz:
https://doaj.org/article/4d0a7cd44dd146b09de0df51daf423a2
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Breast Cancer (BC) is the most common cancer worldwide and, despite the advancements made toward early diagnosis and novel treatments, there is an urgent need to reduce its mortality. The Gastrin-Releasing Peptide Receptor (GRPR) is a promising targe
Externí odkaz:
https://doaj.org/article/d800166837b94aada0fe363fec5401d8
Publikováno v:
Chinese Medicine, Vol 18, Iss 1, Pp 1-17 (2023)
Abstract Many previous studies have shown the potential antipruritic effect of acupuncture. This paper reviews the antipruritic mechanisms of acupuncture according to these aspects: sample characteristics, detail of intervention, and effects evaluati
Externí odkaz:
https://doaj.org/article/6fdced6391fb47bf8067d2dce131face