Zobrazeno 1 - 10
of 55
pro vyhledávání: '"GREG POFFENBERGER"'
Autor:
Diane C. Saunders, Kristie I. Aamodt, Tiffany M. Richardson, Alexander J. Hopkirk, Radhika Aramandla, Greg Poffenberger, Regina Jenkins, David K. Flaherty, Nripesh Prasad, Shawn E. Levy, Alvin C. Powers, Marcela Brissova
Publikováno v:
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-13 (2021)
Abstract Endogenous β cell regeneration could alleviate diabetes, but proliferative stimuli within the islet microenvironment are incompletely understood. We previously found that β cell recovery following hypervascularization-induced β cell loss
Externí odkaz:
https://doaj.org/article/9fc6488438814df2a6871457cb867bcb
Autor:
Shristi Shrestha, Diane C. Saunders, John T. Walker, Joan Camunas-Soler, Xiao-Qing Dai, Rachana Haliyur, Radhika Aramandla, Greg Poffenberger, Nripesh Prasad, Rita Bottino, Roland Stein, Jean-Philippe Cartailler, Stephen C.J. Parker, Patrick E. MacDonald, Shawn E. Levy, Alvin C. Powers, Marcela Brissova
Publikováno v:
JCI Insight, Vol 6, Iss 18 (2021)
Islet-enriched transcription factors (TFs) exert broad control over cellular processes in pancreatic α and β cells, and changes in their expression are associated with developmental state and diabetes. However, the implications of heterogeneity in
Externí odkaz:
https://doaj.org/article/a176612b370447eeb2aad97352fda235
Autor:
John Virostko, Armandla Radhika, Greg Poffenberger, Adrienne N Dula, Daniel J Moore, Alvin C Powers
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57784 (2013)
We generated a mouse model (MIP-Luc-VU-NOD) that enables non-invasive bioluminescence imaging (BLI) of beta cell loss during the progression of autoimmune diabetes and determined the relationship between BLI and disease progression. MIP-Luc-VU-NOD mi
Externí odkaz:
https://doaj.org/article/58031ee0b9074df78da445c8b741b4ca
Autor:
Rachel B Reinert, Jeannelle Kantz, Amanda Ackermann Misfeldt, Greg Poffenberger, Maureen Gannon, Marcela Brissova, Alvin C Powers
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33529 (2012)
Tamoxifen (Tm)-inducible Cre recombinases are widely used to perform gene inactivation and lineage tracing studies in mice. Although the efficiency of inducible Cre-loxP recombination can be easily evaluated with reporter strains, the precise length
Externí odkaz:
https://doaj.org/article/b9e7bb40d84141a3b8e2577ced53c7fa
Autor:
Fouad Atouf, Yong Choi, Michael J. Fowler, Greg Poffenberger, Jan Vobecky, Malancha Ta, George B. Chapman, Alvin C. Powers, Nadya L. Lumelsky
Publikováno v:
Cell Transplantation, Vol 14 (2005)
Transplantation of pancreatic islets can provide long-lasting insulin independence for diabetic patients, but the current islet supply is limited. Here we describe a new in vitro system that utilizes adult human pancreatic islet-enriched fractions to
Externí odkaz:
https://doaj.org/article/024bdd48c4f34001b314fd6d13b8324a
Autor:
John Virostko, Zhongyi Chen, Michael Fowler, Greg Poffenberger, Alvin C. Powers, E. Duco Jansen
Publikováno v:
Molecular Imaging, Vol 3 (2004)
The aim of this study is to determine and characterize factors influencing in vivo bioluminescence imaging (BLI) and apply them to the specific application of imaging transplanted pancreatic islets. Noninvasive quantitative assessment of transplanted
Externí odkaz:
https://doaj.org/article/001ff8bd510c44fbba47e09605412ee7
Autor:
YASMINYE D. PETTWAY, CHUNHUA DAI, TIFFANY M. RICHARDSON, JOHN T. WALKER, RADHIKA ARAMANDLA, GREG POFFENBERGER, AMBER BRADLEY, ALVIN C. POWERS, MARCELA BRISSOVA
Publikováno v:
Diabetes. 71
We previously showed that α cell function and gene expression in islets from donors with type 1 diabetes (T1D) was significantly compromised. The reason (s) for these intrinsic α cell changes are unknown but may include loss of α-to-β cell contac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6575f74600085174a73b23d3699a7b30
https://doi.org/10.2337/db22-367-or
https://doi.org/10.2337/db22-367-or
Autor:
MARCELA BRISSOVA, HEATHER H. DURAI, SHAOJUN MEI, ANASTASIA COLDREN, COREY DAVIS, CONRAD REIHSMANN, ALEXANDER L. HOPKIRK, DANNIELLE GIBSON, RADHIKA ARAMANDLA, GREG POFFENBERGER, DIANE C. SAUNDERS, ALVIN C. POWERS, JOYCE C. NILAND, CARMELLA EVANS-MOLINA
Publikováno v:
Diabetes. 71
The Integrated Islet Distribution Program (IIDP) is currently the largest source of human islets for research in the U.S. The IIDP Human Islet Phenotyping Program (HIPP) provides standardized islet assessment and makes these data available to researc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41e4ee6ead89a24b7c577d918b8ceb78
https://doi.org/10.2337/db22-255-lb
https://doi.org/10.2337/db22-255-lb
Autor:
Robert A. Hegele, Rita Bottino, Nripesh Prasad, Greg Poffenberger, John T. Walker, Marcela Brissova, Shristi Shrestha, Alvin C. Powers, Jenny Aurielle B. Babon, May Sanyoura, Andrea H. Ramirez, Conrad Reihsmann, Louis H. Philipson, Rachana Haliyur, Sally C. Kent, Sambra D. Redick, David M. Harlan, Radhika Aramandla
Publikováno v:
Journal of the Endocrine Society
Clinical and pathologic heterogeneity in type 1 diabetes is increasingly being recognized. Findings in the islets and pancreas of a 22-year-old male with 8 years of type 1 diabetes were discordant with expected results and clinical history (islet aut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a91a34ebaabcfde19db54f1e1fa074f
https://doi.org/10.1210/jendso/bvab162
https://doi.org/10.1210/jendso/bvab162
Autor:
Greg Poffenberger, John T. Walker, Jean-Philippe Cartailler, Xiao-Qing Dai, Nripesh Prasad, Roland Stein, Marcela Brissova, Stephen C. J. Parker, Shawn Levy, Rachana Haliyur, Radhika Aramandla, Shristi Shrestha, Rita Bottino, Joan Camunas-Soler, Alvin C. Powers, Patrick E. MacDonald, Diane C. Saunders
Publikováno v:
JCI Insight
Islet-enriched transcription factors (TFs) exert broad control over cellular processes in pancreatic α and β cells, and changes in their expression are associated with developmental state and diabetes. However, the implications of heterogeneity in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9eea09d136ff7f8673fa2e12b300253
https://doi.org/10.1172/jci.insight.151621
https://doi.org/10.1172/jci.insight.151621