Genetic variation near GRB10 associated with bone growth and osteosarcoma risk in canine and human populations.

Autor: Lucas SE; Preston Robert Tisch Brain Tumor Center, Department of Neurosurgery, Duke University, Durham, NC, USA; Division of Pediatric Hematology/Oncology, Duke University Medical Center, Durham, NC, USA., Yang T; Division of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, Minneapolis, MN, USA; Division of Epidemiology and Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA; Division of Pediatric Hematology/Oncology, Duke University Medical Center, Durham, NC, USA., Wimberly CE; Preston Robert Tisch Brain Tumor Center, Department of Neurosurgery, Duke University, Durham, NC, USA; Division of Pediatric Hematology/Oncology, Duke University Medical Center, Durham, NC, USA., Parmar KV; Preston Robert Tisch Brain Tumor Center, Department of Neurosurgery, Duke University, Durham, NC, USA; Division of Pediatric Hematology/Oncology, Duke University Medical Center, Durham, NC, USA., Hansen HM; Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA, USA; Division of Pediatric Hematology/Oncology, Duke University Medical Center, Durham, NC, USA., de Smith AJ; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, University of Southern California, Los Angeles, CA, USA; Division of Pediatric Hematology/Oncology, Duke University Medical Center, Durham, NC, USA., Morimoto LM; School of Public Health, University of California, Berkeley, Berkeley, CA, USA; Division of Pediatric Hematology/Oncology, Duke University Medical Center, Durham, NC, USA., Metayer C; School of Public Health, University of California, Berkeley, Berkeley, CA, USA; Division of Pediatric Hematology/Oncology, Duke University Medical Center, Durham, NC, USA., Ostrom QT; Preston Robert Tisch Brain Tumor Center, Department of Neurosurgery, Duke University, Durham, NC, USA; Duke Cancer Institute, Duke University, Durham, NC, USA; Division of Pediatric Hematology/Oncology, Duke University Medical Center, Durham, NC, USA., Eward WC; Duke Cancer Institute, Duke University, Durham, NC, USA; Department of Orthopaedic Surgery, Duke University, Durham, NC, USA; Division of Pediatric Hematology/Oncology, Duke University Medical Center, Durham, NC, USA., Graves LA; Department of Pediatrics, Duke University, Durham, NC, USA; Division of Pediatric Hematology/Oncology, Duke University Medical Center, Durham, NC, USA., Wagner LM; Duke Cancer Institute, Duke University, Durham, NC, USA; Department of Pediatrics, Duke University, Durham, NC, USA; Division of Pediatric Hematology/Oncology, Duke University Medical Center, Durham, NC, USA., Wiemels JL; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, University of Southern California, Los Angeles, CA, USA; Division of Pediatric Hematology/Oncology, Duke University Medical Center, Durham, NC, USA., Spector LG; Division of Epidemiology and Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA; Division of Pediatric Hematology/Oncology, Duke University Medical Center, Durham, NC, USA., Walsh KM; Preston Robert Tisch Brain Tumor Center, Department of Neurosurgery, Duke University, Durham, NC, USA; Duke Cancer Institute, Duke University, Durham, NC, USA; Department of Pediatrics, Duke University, Durham, NC, USA; Division of Pediatric Hematology/Oncology, Duke University Medical Center, Durham, NC, USA. Electronic address: Kyle.Walsh@Duke.edu.

Publikováno v: Cancer epidemiology [Cancer Epidemiol] 2024 Oct; Vol. 92, pp. 102599. Date of Electronic Publication: 2024 Jun 12.

Combination of arsenic trioxide and apatinib synergistically inhibits small cell lung cancer by down-regulating VEGFR2/mTOR and Akt/c-Myc signaling pathway via GRB10.

Autor: Yu Y; Harbin Medical University, Harbin, Heilongjiang Province, China.; Department of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China., Shang Y; Department of Respiration, The First Hospital of Harbin, Harbin, Heilongjiang Province, China., Shi S; Harbin Medical University, Harbin, Heilongjiang Province, China.; Department of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China., He Y; Harbin Medical University, Harbin, Heilongjiang Province, China.; Department of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China., Shi W; Harbin Medical University, Harbin, Heilongjiang Province, China.; Department of Pulmonary and Critical Care Medicine, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China., Wang M; Harbin Medical University, Harbin, Heilongjiang Province, China.; Department of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China., Wang Q; Harbin Medical University, Harbin, Heilongjiang Province, China.; Department of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China., Xu D; Harbin Medical University, Harbin, Heilongjiang Province, China.; Department of Geriatric Respiratory Medicine, Heilongjiang Provincial Hospital, Harbin, China., Shi C; NHC Key Laboratory of Cell Transplantation, The First Affiliated Hospital of Harbin Medical University (HMU), Harbin, Heilongjiang Province, China. shice@hrbmu.edu.cn., Chen H; Harbin Medical University, Harbin, Heilongjiang Province, China. yy573879253@126.com.; Department of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China. yy573879253@126.com.

Publikováno v: Hereditas [Hereditas] 2024 Sep 02; Vol. 161 (1), pp. 29. Date of Electronic Publication: 2024 Sep 02.

GRB10 regulates β-cell mass by inhibiting β-cell proliferation and stimulating β-cell dedifferentiation.

Autor: Cai Z; National Clinical Research Center for Metabolic Diseases, Metabolic Syndrome Research Center, Key Laboratory of Diabetes Immunology, Ministry of Education, And Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011 China., Liu F; National Clinical Research Center for Metabolic Diseases, Metabolic Syndrome Research Center, Key Laboratory of Diabetes Immunology, Ministry of Education, And Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011 China., Yang Y; National Clinical Research Center for Metabolic Diseases, Metabolic Syndrome Research Center, Key Laboratory of Diabetes Immunology, Ministry of Education, And Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011 China., Li D; National Clinical Research Center for Metabolic Diseases, Metabolic Syndrome Research Center, Key Laboratory of Diabetes Immunology, Ministry of Education, And Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011 China., Hu S; Department of Urological Organ Transplantation, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, China., Song L; Department of Urological Organ Transplantation, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, China., Yu S; Department of Urological Organ Transplantation, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, China., Li T; Department of Liver Organ Transplantation, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, China., Liu B; National Clinical Research Center for Metabolic Diseases, Metabolic Syndrome Research Center, Key Laboratory of Diabetes Immunology, Ministry of Education, And Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011 China., Luo H; National Clinical Research Center for Metabolic Diseases, Metabolic Syndrome Research Center, Key Laboratory of Diabetes Immunology, Ministry of Education, And Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011 China., Zhang W; Department of Pathophysiology, Naval Medical University, Shanghai 200433, China., Zhou Z; National Clinical Research Center for Metabolic Diseases, Metabolic Syndrome Research Center, Key Laboratory of Diabetes Immunology, Ministry of Education, And Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011 China., Zhang J; National Clinical Research Center for Metabolic Diseases, Metabolic Syndrome Research Center, Key Laboratory of Diabetes Immunology, Ministry of Education, And Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011 China. Electronic address: Doctorzhangjj@csu.edu.cn.

Publikováno v: Journal of genetics and genomics = Yi chuan xue bao [J Genet Genomics] 2022 Mar; Vol. 49 (3), pp. 208-216. Date of Electronic Publication: 2021 Nov 30.

GRB10 sustains AR activity by interacting with PP2A in prostate cancer cells.

Autor: Hao J; Vancouver Prostate Centre, Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Experimental Therapeutics, BC Cancer Agency, Vancouver, British Columbia, Canada., Ci X; Vancouver Prostate Centre, Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Experimental Therapeutics, BC Cancer Agency, Vancouver, British Columbia, Canada., Wang Y; Vancouver Prostate Centre, Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Urology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China., Choi SYC; Vancouver Prostate Centre, Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Experimental Therapeutics, BC Cancer Agency, Vancouver, British Columbia, Canada., Sullivan SE; Vancouver Prostate Centre, Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Kinesiology and Physical Education, McGill University, Quebec, Canada., Xue H; Department of Experimental Therapeutics, BC Cancer Agency, Vancouver, British Columbia, Canada., Wu R; Department of Experimental Therapeutics, BC Cancer Agency, Vancouver, British Columbia, Canada., Dong X; Department of Experimental Therapeutics, BC Cancer Agency, Vancouver, British Columbia, Canada., Haegert AM; Vancouver Prostate Centre, Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Collins CC; Vancouver Prostate Centre, Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Lin D; Vancouver Prostate Centre, Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Experimental Therapeutics, BC Cancer Agency, Vancouver, British Columbia, Canada., Wang Y; Vancouver Prostate Centre, Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Experimental Therapeutics, BC Cancer Agency, Vancouver, British Columbia, Canada.

Publikováno v: International journal of cancer [Int J Cancer] 2021 Jan 15; Vol. 148 (2), pp. 469-480. Date of Electronic Publication: 2020 Oct 21.

CircRNA GRB10 is a Novel Biomarker for the Accurate Diagnosis of Lumbar Degenerative Disc Disease.

Autor: Wei L; Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 200052, People's Republic of China.; Shanghai Guanghua Hospital of Integrative Medicine, Shanghai, 200052, People's Republic of China.; Institute of Arthritis Research in Integrative Medicine, Shanghai Academy of Traditional Chinese Medicine, Shanghai, 200052, People's Republic of China., Guo J; Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 200052, People's Republic of China.; Shanghai Guanghua Hospital of Integrative Medicine, Shanghai, 200052, People's Republic of China.; Institute of Arthritis Research in Integrative Medicine, Shanghai Academy of Traditional Chinese Medicine, Shanghai, 200052, People's Republic of China., Zhai W; Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 200052, People's Republic of China.; Shanghai Guanghua Hospital of Integrative Medicine, Shanghai, 200052, People's Republic of China.; Institute of Arthritis Research in Integrative Medicine, Shanghai Academy of Traditional Chinese Medicine, Shanghai, 200052, People's Republic of China., Xie Y; Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 200052, People's Republic of China.; Shanghai Guanghua Hospital of Integrative Medicine, Shanghai, 200052, People's Republic of China.; Institute of Arthritis Research in Integrative Medicine, Shanghai Academy of Traditional Chinese Medicine, Shanghai, 200052, People's Republic of China., Jia Y; Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 200052, People's Republic of China. yongwei_jia@163.com.; Shanghai Guanghua Hospital of Integrative Medicine, Shanghai, 200052, People's Republic of China. yongwei_jia@163.com.; Institute of Arthritis Research in Integrative Medicine, Shanghai Academy of Traditional Chinese Medicine, Shanghai, 200052, People's Republic of China. yongwei_jia@163.com.; Department of Spinal Surgery, Shanghai Guanghua Hospital of Integrative Medicine, NO.540, Xinhua Road, Changning District, Shanghai, 200052, People's Republic of China. yongwei_jia@163.com.

Publikováno v: Molecular biotechnology [Mol Biotechnol] 2023 May; Vol. 65 (5), pp. 816-821. Date of Electronic Publication: 2022 Oct 17.