Zobrazeno 1 - 10
of 109
pro vyhledávání: '"GR-127935"'
Autor:
Mona Ahmadi, Abbas Tafakhori, Maziar Gooshe, Shayan Amiri, Ahmad Reza Dehpour, Vajiheh Aghamollaii, Keyvan Ghasemi, Mohammad Mojtaba Rohani
Publikováno v:
European journal of pharmacology. 824
Sumatriptan has been among the top choices in the management of migraine headaches. The association between migraine and epilepsy highlights the possible effect of sumatriptan on seizures. In this regard, we investigated sumatriptan effects on PTZ-in
Autor:
S.E. Shortall, Francis J. P. Ebling, Madeleine V. King, Kevin C. F. Fone, Clare H. Spicer, A. Richard Green
Publikováno v:
Addiction Biology. 21:1127-1139
The psychoactive effects of mephedrone are commonly compared with those of 3,4-methylenedioxymethamphetamine, but because of a shorter duration of action, users often employ repeated administration to maintain its psychoactive effects. This study exa
Autor:
Judith R. Homberg, Lara-Jane Kepser
Publikováno v:
Behavioural Brain Research, 277, pp. 3-13
Behavioural Brain Research, 277, 3-13
Behavioural Brain Research, 277, 3-13
Item does not contain fulltext Serotonin is well known for its role in psychiatric disorders like depression and autism, but it is less clear how aberrant behaviour associated with these disorders are shaped by serotonergic alterations during prenata
Publikováno v:
Pharmacology Biochemistry and Behavior. 124:1-4
RU 24969 is a widely used, but non-selective, 5-HT1B/1A agonist that decreases fluid consumption and increases forward locomotion. The mechanism underlying these behavioural responses is not, however, well understood. Accordingly, effects of the sele
Publikováno v:
Psychopharmacology. 231:1191-1200
Perinatal exposure of rats to selective serotonin reuptake inhibitors (SSRIs) produces sensory and social abnormalities paralleling those seen in autistic spectrum disorders (ASDs). However, the possible mechanism(s) by which this exposure produces b
Autor:
Edmund Przegaliński, Joanna Miszkiel
Publikováno v:
Pharmacological Reports. 65:813-822
Numerous data indicated a significance for the brain dopaminergic pathways in the behavioral effects of cocaine, however recent research also demonstrated involvement of serotonin (5-HT) neurotransmission and particularly 5-HT(1B) receptors in the re
Autor:
Bekir Faruk Erden, Furuzan Akar, Ipek Komsuoglu Celikyurt, Guner Ulak, Pelin Tanyeri, Oguz Mutlu
Publikováno v:
Drug Development Research. 74:242-251
Preclinical Research TRIM, a selective neuronal NOS inhibitor, had anxiolytic effects in the elevated plus-maze (EPM) test. The aim of the present study was to evaluate the involvement of serotonergic system in the anxiolytic-like effect of TRIM in t
Publikováno v:
Anesthesia and Analgesia
BACKGROUND: We have recently shown that levetiracetam, administered systemically, exerts an antihyperalgesic effect in a rat inflammatory pain model. In this study, we examined whether levetiracetam has local peripheral antihyperalgesic/antiedematous
Autor:
Natasha Bukholt, Jeremy Webster, Jason Foote, Ross van de Wetering, Dane Aronsen, Susan Schenk, Quenten Highgate
Publikováno v:
Pharmacology, biochemistry, and behavior. 148
Acute exposure to ±3,4-methylenedioxymethamphetamine (MDMA) preferentially increases release of serotonin (5-HT), and a role of 5-HT in many of the behavioral effects of acute exposure to MDMA has been demonstrated. A role of 5-HT in MDMA self-admin
Autor:
Maria J. Guerra, Jannette Rodriguez-Pallares, Juan A. Parga, Ana Muñoz, Jose L. Labandeira-Garcia
Publikováno v:
Journal of Neurobiology. 67:10-22
Inductive signals mediating the differentiation of neural precursors into serotonergic (5-HT) or dopaminergic neurons have not been clarified. We have recently shown that in cell aggregates obtained from rat mesencephalic precursors, reduction of ser