Zobrazeno 1 - 10
of 103
pro vyhledávání: '"GR Dodge"'
Long term outcomes of biomaterial-mediated repair of focal cartilage defects in a large animal model
Autor:
ML Sennett,, JM Friedman, BS Ashley, BD Stoeckl, JM Patel, M Alini, M Cucchiarini, D Eglin, H Madry, A Mata, C Semino, MJ Stoddart, B Johnstone, FT Moutos, BT Estes, F Guilak,, RL Mauck, GR Dodge
Publikováno v:
European Cells & Materials, Vol 41, Pp 40-51 (2021)
The repair of focal cartilage defects remains one of the foremost issues in the field of orthopaedics. Chondral defects may arise from a variety of joint pathologies and left untreated, will likely progress to osteoarthritis. Current repair technique
Externí odkaz:
https://doaj.org/article/d420437fbd064e1bae7368d21c40afeb
Publikováno v:
European Cells & Materials, Vol 38, Pp 23-34 (2019)
Articular cartilage is a specialised tissue that has a relatively homogenous endogenous cell population but a diverse extracellular matrix (ECM), with depth-dependent mechanical properties. Repair of this tissue remains an elusive clinical goal, with
Externí odkaz:
https://doaj.org/article/9957326f640845f0ad89333289f4ebb1
Autor:
B Johnstone, M Alini, M Cucchiarini, GR Dodge, D Eglin, F Guilak, H Madry, A Mata, RL Mauck, CE Semino, MJ Stoddart
Publikováno v:
European Cells & Materials, Vol 25, Pp 248-267 (2013)
Articular cartilage exhibits little capacity for intrinsic repair, and thus even minor injuries or lesions may lead to progressive damage and osteoarthritic joint degeneration, resulting in significant pain and disability. While there have been numer
Externí odkaz:
https://doaj.org/article/fc4c53dbeefd4a2484a0a695b6645839
Autor:
B Johnstone, M Alini, M Cucchiarini, GR Dodge, D Eglin, F Guilak, H Madry, A Mata, RL Mauck, CE Semino, MJ Stoddart
Publikováno v:
European Cells & Materials, Vol 25, Pp 248-267 (2013)
Articular cartilage exhibits little capacity for intrinsic repair, and thus even minor injuries or lesions may lead to progressive damage and osteoarthritic joint degeneration, resulting in significant pain and disability. While there have been numer
Externí odkaz:
https://doaj.org/article/1101ccc7fd1c47e59eccf7b67b4b1711
Autor:
LJ Smith, JA Chiaro, NL Nerurkar, DH Cortes, SD Horava, NM Hebela, RL Mauck, GR Dodge, DM Elliott
Publikováno v:
European Cells & Materials, Vol 22, Pp 291-301 (2011)
Intervertebral disc degeneration is characterized by a cascade of cellular, biochemical and structural changes that may lead to functional impairment and low back pain. Interleukin-1 beta (IL-1β) is strongly implicated in the etiology of disc degene
Externí odkaz:
https://doaj.org/article/70a26d867f1e4194b50076758347ab54
Autor:
Lau YK; Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Iyer K; Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Shetye S; Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Friday CS; Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Dodge GR; Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Mechano Therapeutics LLC, Philadelphia, Pennsylvania, USA., Hast MW; Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Casal ML; Department of Clinical Sciences and Advanced Medicine, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Gawri R; Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Smith LJ; Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society [J Orthop Res] 2024 Jul; Vol. 42 (7), pp. 1409-1419. Date of Electronic Publication: 2024 Feb 18.
Autor:
Whittaker JL; Department of Physical Therapy, University of British Columbia, Vancouver, Canada.; Arthritis Research Canada, Vancouver, Canada., Kalsoum R; Department of Immunology and Inflammation, Imperial College London, London, UK., Bilzon J; Department for Health, University of Bath, Bath, UK.; Centre for Sport, Exercise and Osteoarthritis Research Versus Arthritis, UK., Conaghan PG; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.; NIHR Leeds Biomedical Research Centre, Leeds, UK., Crossley K; La Trobe Sport and Exercise Medicine Research Centre, School of Allied Health, Human Services and Sport, La Trobe University, Melbourne, Australia., Dodge GR; Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Mechano Therapeutics LLC, Philadelphia, PA, USA., Getgood A; Division of Orthopedic Surgery, Bone and Joint Institute, Fowler Kennedy Sport Medicine Clinic, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada., Li X; Program of Advanced Musculoskeletal Imaging (PAMI), Cleveland Clinic, OH, USA.; Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, OH, USA., Losina E; Department of Orthopedic Surgery, Brigham and Women's Hospital, Boston, USA.; Department of Orthopedic Surgery, Harvard Medical School, Boston, USA., Mason DJ; Biomechanics and Bioengineering Research Centre Versus Arthritis, School of Biosciences, Cardiff University, Cardiff, UK., Pietrosimone B; Department of Exercise and Sport Science, University of North Carolina, USA., Risberg MA; Norwegian School Sport Sciences, Oslo, Norway.; Division of Orthopedic Surgery, Oslo University Hospital, Oslo, Norway., Roemer F; Department of Radiology, Universitätsklinikum Erlangen & Friedrich- Alexander-Universität (FAU) Erlangen-Nürnberg, Erlangen, Germany.; Chobanian & Avedisian School of Medicine, Boston University, Boston, MA, USA., Felson D; Section of Rheumatology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Culvenor AG; La Trobe Sport and Exercise Medicine Research Centre, School of Allied Health, Human Services and Sport, La Trobe University, Melbourne, Australia., Meuffels D; Orthopedic and Sport Medicine Department, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Gerwin N; Novartis BioMedical Research, Basel, Switzerland., Simon LS; SDG LLC, Cambridge, MA, USA., Lohmander LS; Department of Clinical Sciences Lund, Orthopaedics, Lund University, Lund, Sweden., Englund M; Department of Clinical Sciences Lund, Orthopaedics, Clinical Epidemiology Unit, Lund University, Lund, Sweden., Watt FE; Department of Immunology and Inflammation, Imperial College London, London, UK.; Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, University of Oxford, UK.
Publikováno v:
Osteoarthritis and cartilage open [Osteoarthr Cartil Open] 2024 Feb 23; Vol. 6 (2), pp. 100449. Date of Electronic Publication: 2024 Feb 23 (Print Publication: 2024).
Autor:
Peredo AP; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.; Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA.; Translational Musculoskeletal Research Center, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA 19104, USA., Gullbrand SE; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.; Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA.; Translational Musculoskeletal Research Center, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA 19104, USA., Friday CS; Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA., Orozco BS; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.; Translational Musculoskeletal Research Center, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA 19104, USA., Dehghani B; Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA.; Translational Musculoskeletal Research Center, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA 19104, USA., Jenk AC; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.; Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA.; Translational Musculoskeletal Research Center, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA 19104, USA., Bonnevie ED; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.; Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA.; Translational Musculoskeletal Research Center, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA 19104, USA., Hilliard RL; Department of Clinical Studies, New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19348, USA., Zlotnick HM; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.; Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA.; Translational Musculoskeletal Research Center, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA 19104, USA., Dodge GR; Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA.; Translational Musculoskeletal Research Center, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA 19104, USA., Lee D; Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, PA 19104, USA., Engiles JB; Department of Clinical Studies, New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19348, USA.; Department of Pathobiology, New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19348, USA., Hast MW; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.; Translational Musculoskeletal Research Center, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA 19104, USA., Schaer TP; Department of Clinical Studies, New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19348, USA., Smith HE; Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA.; Translational Musculoskeletal Research Center, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA 19104, USA., Mauck RL; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.; Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA.; Translational Musculoskeletal Research Center, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA 19104, USA.
Publikováno v:
Science translational medicine [Sci Transl Med] 2023 Nov 15; Vol. 15 (722), pp. eadf1690. Date of Electronic Publication: 2023 Nov 15.
Publikováno v:
Orthopedics [Orthopedics] 2023 Nov-Dec; Vol. 46 (6), pp. e381-e383. Date of Electronic Publication: 2023 May 02.
Autor:
DePhillipo NN; McKay Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA, USA.; Mechano-Therapeutics LLC, Philadelphia, PA, USA., Hendesi H; Department of Orthopedics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Aman ZS; Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA., Lind DRG; McKay Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA, USA., Smith J; Department of Health, Nutrition, and Exercise Sciences, North Dakota State University, Fargo, ND, USA., Dodge GR; McKay Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA, USA.; Mechano-Therapeutics LLC, Philadelphia, PA, USA.
Publikováno v:
Cartilage [Cartilage] 2023 Mar; Vol. 14 (1), pp. 59-66. Date of Electronic Publication: 2022 Dec 21.