Zobrazeno 1 - 10
of 4 817
pro vyhledávání: '"GPx4"'
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Background Cervical cancer is the fourth leading cause of cancer-related death among women worldwide, and effective therapeutic strategies for its treatment are limited. Recent studies have indicated that ferroptosis, a form of regulated cel
Externí odkaz:
https://doaj.org/article/851ac6706d47497f8729ea936680af56
Publikováno v:
BioMedical Engineering OnLine, Vol 23, Iss 1, Pp 1-28 (2024)
Abstract Radiation-induced brain injury (RBI) presents a significant challenge for patients undergoing radiation therapy for head, neck, and intracranial tumors. This review aims to elucidate the role of ferroptosis in RBI and its therapeutic implica
Externí odkaz:
https://doaj.org/article/d4db129ad4c0433994e2ee868aa2cd80
Autor:
Wen-Ting Li, Xin Jin, Sheng-Jie Song, Chong Wang, Chuang Fu, Wen Jiang, Jie Bai, Zhi-Zhou Shi
Publikováno v:
Animal Cells and Systems, Vol 28, Iss 1, Pp 237-250 (2024)
ABSTRACTThe role of ferroptosis-associated gene SLC7A11 in esophageal cancer progression is largely unknown, therefore, the effects of blocking SLC7A11 on esophageal squamous cell carcinoma (ESCC) cells are evaluated. Results showed that SLC7A11 was
Externí odkaz:
https://doaj.org/article/64dd97c009fd4ca3a3ff37d2838c93b5
Publikováno v:
Pharmaceutical Biology, Vol 62, Iss 1, Pp 195-206 (2024)
AbstractContext Cephaeline is a natural product isolated from ipecac (Cephaelis ipecacuanha [Brot.] A. Rich. [Rubiaceae]). It exhibits promising anti-lung cancer activity and ferroptosis induction may be a key mechanism for its anti-lung cancer effec
Externí odkaz:
https://doaj.org/article/9344319bee344dabbb8fdf461e93a930
Publikováno v:
BMC Gastroenterology, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background Ferroptosis is a newly recognized form of regulatory cell death characterized by severe lipid peroxidation triggered by iron overload and the production of reactive oxygen species (ROS). However, the role of ferroptosis in severe
Externí odkaz:
https://doaj.org/article/e3ae6680e8dc4e67878f2836ae86e029
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract To analyze the mechanism of how interfering with the cytokeratin 19 (CK19) pathway via the ferroptosis pathway affects tumor biological behaviors in the process of oral squamous cell carcinoma (OSCC) development. TCGA was used to analyze the
Externí odkaz:
https://doaj.org/article/7c39195f1b8c46fea319023fc0c9401a
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-15 (2024)
Abstract Phospholipid Hydroperoxide Gluthatione Peroxidase also called Glutathione Peroxidase 4 is one of the 25 described human selenoproteins. It plays an essential role in eliminating toxic lipid hydroxy peroxides, thus inhibiting ferroptosis and
Externí odkaz:
https://doaj.org/article/13144bc4693b42e1967ff459c25f9d24
Autor:
Si-Chun Gu, Zhi-Guo Xie, Min-Jue Gu, Chang-De Wang, Li-Min Xu, Chen Gao, Xiao-Lei Yuan, You Wu, Yu-Qing Hu, Yang Cao, Qing Ye
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Ferroptosis is an iron-dependent cell death form characterized by reactive oxygen species (ROS) overgeneration and lipid peroxidation. Myricetin, a flavonoid that exists in numerous plants, exhibits potent antioxidant capacity. Given that ir
Externí odkaz:
https://doaj.org/article/567dadeeddc8448591074dfab12253a0
Publikováno v:
Tobacco Induced Diseases, Vol 22, Iss June, Pp 1-8 (2024)
Introduction The essence of ferroptosis is the accumulation of membrane lipid peroxides caused by increased iron, which disrupts the redox balance within cells and triggers cell death. Abnormal metabolism of iron significantly increases the risk of l
Externí odkaz:
https://doaj.org/article/74c6145d9bd94bbdb60c9d063e79cc03
Autor:
Jinxin Xie, Huiming Huang, Xuejiao Wei, Peng Tan, Lishan Ouyang, Longyan Wang, Dongxiao Liu, Fei Wang, Zhuguo Wang, Pengfei Tu, Jun Li, Xiaojun Zha, Zhongdong Hu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Breast cancer (BC) remains a significant health concern for women globally, prompting the relentless pursuit of novel therapeutic modalities. As a traditional Chinese medicine, Boswellia carterii has been extensively used to treat various ca
Externí odkaz:
https://doaj.org/article/89cb363f67984564bf7272c1480f958c