Zobrazeno 1 - 10
of 227
pro vyhledávání: '"GPx, glutathione peroxidase"'
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2749-2767 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2749-2767 (2021)
Diabetic nephropathy (DN) has been recognized as a severe complication of diabetes mellitus and a dominant pathogeny of end-stage kidney disease, which causes serious health problems and great financial burden to human society worldwide. Conventional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68d8ab4193adc39b242fa3c089b4f517
https://doi.org/10.1016/j.apsb.2020.12.020
https://doi.org/10.1016/j.apsb.2020.12.020
Autor:
Lakmini Mudduwa, Kamani Ayoma Perera Wijewardana Jayatilaka, Jayasinghe Arachchige Nirosha Sandamali, Ruwani Punyakanthi Hewawasam
Publikováno v:
Saudi Pharmaceutical Journal, Vol 29, Iss 8, Pp 820-832 (2021)
Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal : SPJ
Anti-tumour efficacy of doxorubicin is hindered by the cumulative dose-dependent cardiotoxicity induced by reactive oxygen species during its metabolism. As Cinnamomum zeylanicum has proven antioxidant potential, objective of this study was to invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07ec834331604e75cffd6b67e9822c83
http://www.sciencedirect.com/science/article/pii/S1319016421001183
http://www.sciencedirect.com/science/article/pii/S1319016421001183
Autor:
O. Bamidele, Olugbenga Samuel Michael, Charles Oluwaseun Adetunji, Olufemi Idowu Oluranti, Pamela Ogheneovo, Temitope A. Ariyo, F.O. Awobajo, Lawrence Dayo Adedayo, Elizabeth O. Soladoye
Publikováno v:
Current Research in Physiology, Vol 4, Iss, Pp 252-259 (2021)
Current Research in Physiology
Current Research in Physiology
Lead acetate associated tissue injury has been linked to altered antioxidant defenses, hyperuricemia and inflammation. We hypothesized that watermelon rind extract, would ameliorate lead acetate-induced hepato-renal injury. Thirty Male Wistar rats re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f109d3aa2807980a87ad5190908bae87
http://www.sciencedirect.com/science/article/pii/S2665944121000304
http://www.sciencedirect.com/science/article/pii/S2665944121000304
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 1177-1197 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 1177-1197 (2021)
Inflammatory bowel disease (IBD) patients have an increased risk of developing colitis-associated colon cancer (CAC); however, the basis for inflammation-induced genetic damage requisite for neoplasia is unclear. Several studies have shown that IBD p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f8c79d5f17568276f485aec45f7d118
http://europepmc.org/articles/PMC7907812
http://europepmc.org/articles/PMC7907812
Autor:
Anuar Salazar-Gómez, Saudy Saret Pablo-Pérez, M. Elena Vargas-Dı́az, Julio C. Ontiveros-Rodríguez, Leticia Garduño-Siciliano
Publikováno v:
South African Journal of Botany
Highlights • Definition and pathogenesis of metabolic syndrome is briefly described. • Sesquiterpene lactones isolated from medicinal plants used in traditional medicine. • In vivo and in vitro biological activities of sesquiterpene lactones ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::512583e8aceec7a8d3995bc13c6d8a6c
https://doi.org/10.1016/j.sajb.2020.08.020
https://doi.org/10.1016/j.sajb.2020.08.020
Publikováno v:
Saudi Journal of Biological Sciences, Vol 27, Iss 9, Pp 2251-2260 (2020)
Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences
Doxorubicin (DOX) is an anthracycline drug used for cancer treatment. However, its treatment is contiguous with toxic effects. We examine the nephroprotective potential of A. hydaspica polyphenol-rich ethyl acetate extract (AHE) against DOX persuaded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89d76d10a2004f5cf7b12979a7290a99
http://www.sciencedirect.com/science/article/pii/S1319562X20303028
http://www.sciencedirect.com/science/article/pii/S1319562X20303028
Autor:
Saeed Alshahrani, Fakhrul Islam, Rahimullah Siddiqui, Mohammed Ashafaq, Rayan A Ahmed, Sohail Hussain, Gulrana Khuwaja
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 7, Iss, Pp 1296-1304 (2020)
Toxicology Reports, Vol 7, Iss, Pp 1296-1304 (2020)
Graphical abstract
Acetaminophen (APAP) is used as a primary drug due to its antipyretic and analgesic activity. The mechanism of action of APAP toxicity in the liver is due to the depletion of glutathione which elicited free radicals generation
Acetaminophen (APAP) is used as a primary drug due to its antipyretic and analgesic activity. The mechanism of action of APAP toxicity in the liver is due to the depletion of glutathione which elicited free radicals generation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ccb153456c1b85f9ee1f88a05b7acd1
http://europepmc.org/articles/PMC7528057
http://europepmc.org/articles/PMC7528057
Publikováno v:
The British Journal of Nutrition
British Journal of Nutrition
British Journal of Nutrition
Se is a micronutrient essential for human health. Sub-optimal Se status is common, occurring in a significant proportion of the population across the world including parts of Europe and China. Human and animal studies have shown that Se status is a k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbaf9f791d4be7223448b47e450803a1
http://europepmc.org/articles/PMC7503044
http://europepmc.org/articles/PMC7503044
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 7, Iss, Pp 730-742 (2020)
Toxicology Reports, Vol 7, Iss, Pp 730-742 (2020)
Graphical abstract
Highlights • Hypothyroidism is the most frequent toxic effect of a large variety of chemical compounds. • The polyherbal bioactive fraction exhibited a pro-thyroid effect in hypothyroidic rats. • The polyherbal fraction
Highlights • Hypothyroidism is the most frequent toxic effect of a large variety of chemical compounds. • The polyherbal bioactive fraction exhibited a pro-thyroid effect in hypothyroidic rats. • The polyherbal fraction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58a037e2fd9e28edc68e1ec8b7e6fd1a
http://europepmc.org/articles/PMC7301176
http://europepmc.org/articles/PMC7301176
Autor:
Adrita Banerjee, Aindrila Chattopadhyay, Tiyasa Dey, Arnab Kumar Ghosh, Sanatan Mishra, Debasish Bandyopadhyay
Publikováno v:
Toxicology Reports, Vol 7, Iss, Pp 1551-1563 (2020)
Toxicology Reports
Toxicology Reports
Graphical abstract
Highlights • Phenylhydrazine induces structural and functional changes in erythrocytes. • Oleic acid ameliorates these changes possibly through its antioxidant mechanisms. • Oleic acid can be a benefitting molecule in co
Highlights • Phenylhydrazine induces structural and functional changes in erythrocytes. • Oleic acid ameliorates these changes possibly through its antioxidant mechanisms. • Oleic acid can be a benefitting molecule in co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0793744238a1cd482d4f34df74021edf
http://www.sciencedirect.com/science/article/pii/S2214750020304303
http://www.sciencedirect.com/science/article/pii/S2214750020304303