Zobrazeno 1 - 10 of 33 pro vyhledávání: '"GPI-Linked Protein"'
2
Identification of cell surface targets for CAR-T cell therapies and antibody-drug conjugates in breast cancer
Autor: Fara Brasó-Maristany, Laia Paré, D. Martinez, Francesco Schettini, S. De Placido, Patricia Galván, S. Guedan, Andreu Prat, P. Barbao
Publikováno v: ESMO Open
Background Two promising therapeutic strategies in oncology are chimeric antigen receptor-T cell (CAR-T) therapies and antibody–drug conjugates (ADCs). To be effective and safe, these immunotherapies require surface antigens to be sufficiently expr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2c00f3bcdf4eed8bc722eefa019821c
http://hdl.handle.net/2445/193593
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3
Akademický článek
Spontaneous Incorporation of the Glycosyl-Phosphatidylinositol-Linked Protein Thy-1 into Cell Membranes
Autor: Zhang, Fen, Schmidt, William G., Hou, Yu, Williams, Alan F., Jacobson, Ken
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 1992 Jun . 89(12), 5231-5235.
Externí odkaz: https://www.jstor.org/stable/2359626
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4
Bio-guided fractionation of stem bark extracts from phyllanthus muellarianus: Identification of phytocomponents with anti-cholinesterase activity
Autor: Marina Naldi, Caterina Temporini, Vincenza Andrisano, Manuela Bartolini, Gabriella Massolini, Gloria Brusotti
Publikováno v: Molecules
Volume 26
Issue 14
Molecules, Vol 26, Iss 4376, p 4376 (2021)
A combination of flash chromatography, solid phase extraction, high-performance liquid chromatography, and in vitro bioassays was used to isolate phytocomponents endowed with anticholinesterase activity in extract from Phyllanthus muellarianus. Phyto
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fc07d79fde5502706428e0506300ab5
http://hdl.handle.net/11585/855796
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6
New Insights into Cancer Targeted Therapy: Nodal and Cripto-1 as Attractive Candidates
Autor: Paola Arboretto, Antonio Leonardi, Michele Cillo
Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 7838, p 7838 (2021)
The transforming growth factor beta (TGF-β) signaling is fundamental for correct embryonic development. However, alterations of this pathway have been correlated with oncogenesis, tumor progression and sustaining of cancer stem cells (CSCs). Cripto-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78caeed0d34e08dba777a7260a600797
https://doi.org/10.3390/ijms22157838
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7
Differential expression of CD73, CD86 and CD304 in normal vs. leukemic B-cell precursors and their utility as stable minimal residual disease markers in childhood B-cell precursor acute lymphoblastic leukemia
Autor: Alita J. van der Sluijs-Gelling, Jacques J.M. van Dongen, Prisca M J Theunissen, Vincent H.J. van der Velden, Michaela Novakova, Łukasz Sędek, Alberto Orfao, Ester Mejstrikova, Chiara Buracchi, Tomasz Szczepański, Giuseppe Gaipa, Magdalena Twardoch, Elen Oliveira, Alicja Sonsala, Elaine Sobral da Costa
Publikováno v: Journal of Immunological Methods, 475. ELSEVIER
Digital.CSIC. Repositorio Institucional del CSIC
instname
Journal of Immunological Methods, 475:Unsp 112429. Elsevier
On behalf of the EuroFlow Consortium.
[Background]: Optimal discrimination between leukemic blasts and normal B-cell precursors (BCP) is critical for treatment monitoring in BCP acute lymphoblastic leukemia (ALL); thus identification of markers
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7cb40fd67ebc73282c50a36341c51c1
http://hdl.handle.net/10261/219667
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8
Synergistic inactivation of AXL: a (cross)road to cure ovarian cancer?
Autor: Chiara Zurzolo
Publikováno v: EMBO Reports
EMBO Reports, 2018, 19 (8), pp.e46492. ⟨10.15252/embr.201846492⟩
EMBO Reports, EMBO Press, 2018, 19 (8), pp.e46492. ⟨10.15252/embr.201846492⟩
In ovarian cancer, the prometastatic RTK AXL promotes motility, invasion and poor prognosis. Here, we show that reduced survival caused by AXL overexpression can be mitigated by the expression of the GPI-anchored tumour suppressor OPCML Further, we d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f76655fb1496f0c57da314405f66b9ee
https://hal-pasteur.archives-ouvertes.fr/pasteur-02263624
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9
Organization of GPI-anchored proteins at the cell surface and its physiopathological relevance
Autor: Simona Paladino, Stéphanie Lebreton, Chiara Zurzolo
Publikováno v: Critical Reviews in Biochemistry and Molecular Biology
Critical Reviews in Biochemistry and Molecular Biology, Taylor & Francis, 2018, 53 (4), pp.403-419. ⟨10.1080/10409238.2018.1485627⟩
Critical Reviews in Biochemistry and Molecular Biology, 2018, 53 (4), pp.403-419. ⟨10.1080/10409238.2018.1485627⟩
International audience; Glycosylphosphatidylinositol (GPI)-anchored proteins (GPI-APs) are a class of proteins attached to the extracellular leaflet of the plasma membrane via a post-translational modification, the glycolipid anchor. The presence of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07239b7e06aa62d73c0a7254c40ac7b0
https://hal-pasteur.archives-ouvertes.fr/pasteur-02263637
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10
New Anti-Nodal Monoclonal Antibodies Targeting the Nodal Pre-Helix Loop Involved in Cripto-1 Binding
Autor: Giuseppina Focà, Antonio Leonardi, Mary J.C. Hendrix, Menotti Ruvo, Annalia Focà, Rosanna Palumbo, Roberta Iannitti, Annamaria Sandomenico, Luigi Strizzi, Luca Sanguigno
Publikováno v: International Journal of Molecular Sciences
Volume 16
Issue 9
Pages 21342-21362
International Journal of Molecular Sciences, Vol 16, Iss 9, Pp 21342-21362 (2015)
International journal of molecular sciences (Online) 16 (2015): 21342–62. doi:10.3390/ijms160921342
info:cnr-pdr/source/autori:Foca, Annalia; Sanguigno, Luca; Foca, Giuseppina; Strizzi, Luigi; Iannitti, Roberta; Palumbo, Rosanna; Hendrix, Mary J C; Leonardi, Antonio; Ruvo, Menotti; Sandomenico, Annamaria/titolo:New Anti-Nodal Monoclonal Antibodies Targeting the Nodal Pre-Helix Loop Involved in Cripto-1 Binding./doi:10.3390%2Fijms160921342/rivista:International journal of molecular sciences (Online)/anno:2015/pagina_da:21342/pagina_a:62/intervallo_pagine:21342–62/volume:16
Nodal is a potent embryonic morphogen belonging to the TGF-beta superfamily. Typically, it also binds to the ALK4/ActRIIB receptor complex in the presence of the co-receptor Cripto-1. Nodal expression is physiologically restricted to embryonic tissue
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a3aa1f8b6a4b3a935c2e53b5eb606ee
https://doi.org/10.3390/ijms160921342
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