Zobrazeno 1 - 10
of 664
pro vyhledávání: '"GPCR coupling"'
Publikováno v:
In Current Opinion in Structural Biology June 2023 80
Publikováno v:
In Trends in Biochemical Sciences July 2022 47(7):570-581
Autor:
Okashah, Najeah, Wan, Qingwen, Ghosh, Soumadwip, Sandhu, Manbir, Inoue, Asuka, Vaidehi, Nagarajan, Lambert, Nevin A.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2019 Jun 01. 116(24), 12054-12059.
Externí odkaz:
https://www.jstor.org/stable/26743518
Akademický článek
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Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-16 (2018)
Abstract Background Animal opsins are light-sensitive G-protein-coupled receptors (GPCRs) that enable optogenetic control over the major heterotrimeric G-protein signaling pathways in animal cells. As such, opsins have potential applications in both
Externí odkaz:
https://doaj.org/article/6e01465ae3e94446a265571133022730
Autor:
Bohn, Laura M., McDonald, Patricia H.
Publikováno v:
In Drug Discovery Today: Technologies 2010 7(1):e37-e42
Autor:
Ballister, Edward R.1, Rodgers, Jessica1, Martial, Franck1, Lucas, Robert J.1 arobert.lucas@manchester.ac.uk
Publikováno v:
BMC Biology. 1/16/2018, Vol. 16, p1-N.PAG. 16p.
Publikováno v:
Current Opinion in Structural Biology. 80:102574
Over the past three years (2020–2022) more structures of GPCRs have been determined than in the previous twenty years (2000–2019), primarily of GPCR complexes that are large enough for structure determination by single-particle cryo-EM. This revi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60c449f96f4d475a89cfb51ab60b42cd
https://doi.org/10.1016/j.sbi.2023.102574
https://doi.org/10.1016/j.sbi.2023.102574
Publikováno v:
Trends Biochem Sci
Three classes of G-protein-coupled receptor (GPCR) partners - G proteins, GPCR kinases, and arrestins - preferentially bind active GPCRs. Our analysis suggests that the structures of GPCRs bound to these interaction partners available today do not re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::198f3e9abca8083845695aff859da1f9
https://pubmed.ncbi.nlm.nih.gov/35396120
https://pubmed.ncbi.nlm.nih.gov/35396120
Autor:
Qingwen Wan, Manbir Sandhu, Najeah Okashah, Nagarajan Vaidehi, Soumadwip Ghosh, Nevin A. Lambert, Asuka Inoue
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance G protein-coupled receptors (GPCRs) regulate a wide variety of important cellular processes and are targeted by a large fraction of approved drugs. GPCRs signal by activating heterotrimeric G proteins and must couple to a select subset o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68c4f5ae872953492628b1586f0baed3
http://hdl.handle.net/10097/00128250
http://hdl.handle.net/10097/00128250