Zobrazeno 1 - 10
of 327
pro vyhledávání: '"GPCR (G protein coupled receptor)"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/026e4b553f4144019a1b103dda3cce3f
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/32824537ba4c4359a25f7b4783de0fd7
Autor:
Hongmei Ruan, Ravi Mandla, Namita Ravi, Giselle Galang, Amanda W. Soe, Jeffrey E. Olgin, Di Lang, Vasanth Vedantham
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Aims: The behavior of pacemaker cardiomyocytes (PCs) in the sinoatrial node (SAN) is modulated by neurohormonal and paracrine factors, many of which signal through G-protein coupled receptors (GPCRs). The aims of the present study are to catalog GPCR
Externí odkaz:
https://doaj.org/article/5fac3ba2faa4412db4bddc0a2cf1ffcd
Autor:
Ester Paolocci, Manuela Zaccolo
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
cAMP is a universal second messenger that relies on precise spatio-temporal regulation to control varied, and often opposing, cellular functions. This is achieved via selective activation of effectors embedded in multiprotein complexes, or signalosom
Externí odkaz:
https://doaj.org/article/a560dfbc1ea24ec4b9bde75ba96fd1bb
Autor:
Isabella Marie Jamu, Haruko Okamoto
Publikováno v:
Frontiers in Global Women's Health, Vol 3 (2022)
It has been acknowledged that more women suffer from adverse effects of drugs than men globally. A group of drugs targeting serotonin [5-hydroxytryptamine] (5-HT) binding G-protein-coupled receptors (GPCRs) have been reported to preferentially affect
Externí odkaz:
https://doaj.org/article/2ef20bf556384fc79bb8d5c1f2d43dac
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/3c8bf0c0e19d40af93eb582d87932e87
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
G protein-coupled receptors (GPCRs) are the largest class of membrane proteins and the most common and extensively studied pharmacological target. Numerous studies over the last decade have confirmed that GPCRs do not only exist and function in their
Externí odkaz:
https://doaj.org/article/6009c8caf86c4062974c96e84a7b9514
Autor:
Peter Lindquist, Lærke Smidt Gasbjerg, Jacek Mokrosinski, Jens Juul Holst, Alexander Sebastian Hauser, Mette Marie Rosenkilde
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
The intestinal hormone, glucose-dependent insulinotropic polypeptide (GIP), is involved in important physiological functions, including postprandial blood glucose homeostasis, bone remodeling, and lipid metabolism. While mutations leading to physiolo
Externí odkaz:
https://doaj.org/article/bf18da93d2c844fc905f0c8e2a199121
Autor:
Stephen J Smith, Mark von Zastrow
Publikováno v:
Frontiers in Neural Circuits, Vol 16 (2022)
Adaptive neuronal circuit function requires a continual adjustment of synaptic network parameters known as “neuromodulation.” This process is now understood to be based primarily on the binding of myriad secreted “modulatory” ligands such as
Externí odkaz:
https://doaj.org/article/9e46a02134d249a08c7ce834541b33eb
Autor:
Gongsheng Yuan, Shuying Yang
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Regulator of G protein signaling (RGS) proteins are critical negative molecules of G protein-coupled receptor (GPCR) signaling, which mediates a variety of biological processes in bone homeostasis and diseases. The RGS proteins are divided into nine
Externí odkaz:
https://doaj.org/article/a5ac1267f01a42fa911b18305361c8d4