Zobrazeno 1 - 10
of 51
pro vyhledávání: '"GONGSHENG YUAN"'
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-8 (2023)
Abstract Foxo1 upregulation is linked to defective fracture healing under diabetic conditions. Previous studies demonstrated that diabetes upregulates Foxo1 expression and activation and diabetes impairs ciliogenesis resulting in defective fracture r
Externí odkaz:
https://doaj.org/article/0bd42a1be2e54b4e9d3b91d023402d68
Publikováno v:
Cell Insight, Vol 2, Iss 6, Pp 100102- (2023)
Externí odkaz:
https://doaj.org/article/45a1ceb1b24c47e3b9457876be459ad1
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 31, Iss , Pp 197-210 (2023)
Synovial fibroblasts are the active and aggressive drivers in the progression of arthritis, but the cellular and molecular mechanisms remain unknown. Here, our results showed that regulator of G protein signaling 12 (RGS12) maintained ciliogenesis in
Externí odkaz:
https://doaj.org/article/9cc8807bf1d94c02b448b0faec367f10
Publikováno v:
International Journal of Oral Science, Vol 15, Iss 1, Pp 1-11 (2023)
Abstract Tumor-associated macrophages (TAMs) play crucial roles in tumor progression and immune responses. However, mechanisms of driving TAMs to antitumor function remain unknown. Here, transcriptome profiling analysis of human oral cancer tissues i
Externí odkaz:
https://doaj.org/article/db72b2a7b0ff49bca0891dfa8e6124ca
Publikováno v:
Bone Research, Vol 10, Iss 1, Pp 1-16 (2022)
Abstract Type II collagen-positive (Col2+) cells have been reported as skeletal stem cells (SSCs), but the contribution of Col2+ progenitors to skeletal development both prenatally and postnatally during aging remains unclear. To address this questio
Externí odkaz:
https://doaj.org/article/028db2a9347a4e04a472709603d9f579
Publikováno v:
Cancer Communications, Vol 42, Iss 1, Pp 60-64 (2022)
Externí odkaz:
https://doaj.org/article/99ee9e8c8de544159435dc7eb2103cb8
Publikováno v:
Cell Insight, Vol 1, Iss 5, Pp 100055- (2022)
Angiogenesis is the formation of new capillaries that plays an essential role in the pathogenesis of inflammatory arthritis. However, the cellular and molecular mechanisms remain unclear. Here, we provide the first evidence that regulator of G-protei
Externí odkaz:
https://doaj.org/article/e20b069db4fc46b1a5f4aff74f9d0cfa
Autor:
Gongsheng Yuan, Shuying Yang
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Regulator of G protein signaling (RGS) proteins are critical negative molecules of G protein-coupled receptor (GPCR) signaling, which mediates a variety of biological processes in bone homeostasis and diseases. The RGS proteins are divided into nine
Externí odkaz:
https://doaj.org/article/a5ac1267f01a42fa911b18305361c8d4
Autor:
Hyeran Helen Jeon, Jessica Kang, Jiahui (Madelaine) Li, Douglas Kim, Gongsheng Yuan, Nicolette Almer, Min Liu, Shuying Yang
Publikováno v:
Life, Vol 12, Iss 8, p 1147 (2022)
Osteocytes are the main mechanosensory cells during orthodontic and physiologic bone remodeling. However, the question of how osteocytes transmit mechanical stimuli to biological responses remains largely unanswered. Intraflagellar transport (IFT) pr
Externí odkaz:
https://doaj.org/article/0c30c09903754c28b641c534582ad7a1
Autor:
Gongsheng Yuan, Shuting Yang, Andrew Ng, Chuanyun Fu, Merry Jo Oursler, Lianping Xing, Shuying Yang
Publikováno v:
iScience, Vol 23, Iss 6, Pp 101172- (2020)
Summary: Rheumatoid arthritis (RA) is the most common inflammatory disease, which currently lacks effective treatment. Here, we discovered that the Regulator of G Protein Signaling 12 (RGS12) plays a key role in regulating inflammation. Transcription
Externí odkaz:
https://doaj.org/article/4a5830d2ce714f8eb0de51b614da0fb7