Neutralizing antibody creation technologies: case of SARS-CoV-2

Autor: VP Baklaushev, EM Samoilova, SM Kuznetsova, EV Ermolaeva, GM Yusubalieva, VA Kalsin, AV Lipatova, AV Troitsky

Publikováno v: Medicine of Extreme Situations.

Monoclonal antibodies (mAbs) are the most promising and most intensively replenished type of bioactive pharmaceuticals. Currently, there are over 100 different mAbs approved by the FDA and other regulating agencies for treatment of oncological, infec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7cac4d54db536d84beecf1d2b714991b
https://doi.org/10.47183/mes.2022.049

Novel B-Cell Epitopes of Non-Neutralizing Antibodies in the Receptor-Binding Domain of the SARS-CoV-2 S-Protein with Different Effects on the Severity of COVID-19.

Autor: Matveev AL; Federal State Public Scientific Institution 'Institute of Chemical Biology and Fundamental Medicine', Siberian Branch of the Russian Academy of Sciences, Novosibirsk, 630090, Russia. guterus@gmail.com., Pyankov OV; State Research Center of Virology and Biotechnology 'VECTOR', Federal Service for the Oversight of Consumer Protection and Welfare, Koltsovo, 630559, Novosibirsk Region, Russia., Khlusevich YA; Federal State Public Scientific Institution 'Institute of Chemical Biology and Fundamental Medicine', Siberian Branch of the Russian Academy of Sciences, Novosibirsk, 630090, Russia., Tyazhelkova OV; Federal State Public Scientific Institution 'Institute of Chemical Biology and Fundamental Medicine', Siberian Branch of the Russian Academy of Sciences, Novosibirsk, 630090, Russia., Emelyanova LA; Federal State Public Scientific Institution 'Institute of Chemical Biology and Fundamental Medicine', Siberian Branch of the Russian Academy of Sciences, Novosibirsk, 630090, Russia., Timofeeva AM; Federal State Public Scientific Institution 'Institute of Chemical Biology and Fundamental Medicine', Siberian Branch of the Russian Academy of Sciences, Novosibirsk, 630090, Russia., Shipovalov AV; State Research Center of Virology and Biotechnology 'VECTOR', Federal Service for the Oversight of Consumer Protection and Welfare, Koltsovo, 630559, Novosibirsk Region, Russia., Chechushkov AV; Federal State Public Scientific Institution 'Institute of Chemical Biology and Fundamental Medicine', Siberian Branch of the Russian Academy of Sciences, Novosibirsk, 630090, Russia., Zaitseva NS; FIC FTM, Novosibirsk, 630117, Russia., Kudrov GA; State Research Center of Virology and Biotechnology 'VECTOR', Federal Service for the Oversight of Consumer Protection and Welfare, Koltsovo, 630559, Novosibirsk Region, Russia., Yusubalieva GM; Federal Research and Clinical Center of Specialized Medical Care and Medical Technologies FMBA of Russia, Moscow, 115682, Russia.; Federal Center of Brain Research and Neurotechnologies, FMBA of Russia, Moscow, 117513, Russia., Yussubaliyeva SM; Astana Medical University, Nur-Sultan, 010000, Kazakhstan., Zhukova OA; Federal Research and Clinical Center of Specialized Medical Care and Medical Technologies FMBA of Russia, Moscow, 115682, Russia., Tikunov AY; Federal State Public Scientific Institution 'Institute of Chemical Biology and Fundamental Medicine', Siberian Branch of the Russian Academy of Sciences, Novosibirsk, 630090, Russia., Baklaushev VP; Federal Research and Clinical Center of Specialized Medical Care and Medical Technologies FMBA of Russia, Moscow, 115682, Russia.; Pulmonology Research Institute FMBA of Russia, Moscow, 115682, Russia.; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia., Sedykh SE; Novosibirsk State University, Novosibirsk, 630090, Russia., Lifshits GI; Federal State Public Scientific Institution 'Institute of Chemical Biology and Fundamental Medicine', Siberian Branch of the Russian Academy of Sciences, Novosibirsk, 630090, Russia., Tikunova NV; Federal State Public Scientific Institution 'Institute of Chemical Biology and Fundamental Medicine', Siberian Branch of the Russian Academy of Sciences, Novosibirsk, 630090, Russia.; Novosibirsk State University, Novosibirsk, 630090, Russia.

Publikováno v: Biochemistry. Biokhimiia [Biochemistry (Mosc)] 2023 Sep; Vol. 88 (9), pp. 1205-1214.

Alterations in the CD56 ^- and CD56 ⁺ T Cell Subsets during COVID-19.

Autor: Vavilova JD; Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Ustiuzhanina MO; Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.; Center of Life Sciences, Skolkovo Institute of Science and Technology, 121205 Moscow, Russia., Boyko AA; Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Streltsova MA; Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Kust SA; Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Kanevskiy LM; Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Iskhakov RN; Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Sapozhnikov AM; Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Gubernatorova EO; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia., Drutskaya MS; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.; Division of Immunobiology and Biomedicine, Sirius University of Science and Technology, Sirius, Krasnodarsky Krai, 354349 Sochi, Russia., Bychinin MV; Federal Research and Clinical Center of Specialized Medical Care and Medical Technologies FMBA of Russia, 115682 Moscow, Russia., Novikova ON; Federal Research and Clinical Center of Specialized Medical Care and Medical Technologies FMBA of Russia, 115682 Moscow, Russia., Sotnikova AG; Federal Research and Clinical Center of Specialized Medical Care and Medical Technologies FMBA of Russia, 115682 Moscow, Russia., Yusubalieva GM; Federal Research and Clinical Center of Specialized Medical Care and Medical Technologies FMBA of Russia, 115682 Moscow, Russia.; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia., Baklaushev VP; Federal Research and Clinical Center of Specialized Medical Care and Medical Technologies FMBA of Russia, 115682 Moscow, Russia.; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia., Kovalenko EI; Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 May 20; Vol. 24 (10). Date of Electronic Publication: 2023 May 20.

Oncolytic Efficacy of a Recombinant Vaccinia Virus Strain Expressing Bacterial Flagellin in Solid Tumor Models.

Autor: Shakiba Y; Moscow Institute of Physics and Technology, 141701 Dolgoprudny, Russia.; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia., Vorobyev PO; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia., Naumenko VA; Department of Neurobiology, V. Serbsky Federal Medical Research Centre of Psychiatry and Narcology of the Ministry of Health of the Russian Federation, 119034 Moscow, Russia., Kochetkov DV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia., Zajtseva KV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia., Valikhov MP; Department of Neurobiology, V. Serbsky Federal Medical Research Centre of Psychiatry and Narcology of the Ministry of Health of the Russian Federation, 119034 Moscow, Russia.; Department of Medical Nanobiotechnology, Pirogov Russian National Research Medical University, 117997 Moscow, Russia., Yusubalieva GM; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.; Federal Research and Clinical Center for Specialized Types of Medical Care and Medical Technologies FMBA of Russia, 115682 Moscow, Russia., Gumennaya YD; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia., Emelyanov EA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia., Semkina AS; Department of Medical Nanobiotechnology, Pirogov Russian National Research Medical University, 117997 Moscow, Russia., Baklaushev VP; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.; Federal Research and Clinical Center for Specialized Types of Medical Care and Medical Technologies FMBA of Russia, 115682 Moscow, Russia., Chumakov PM; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia., Lipatova AV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.

Publikováno v: Viruses [Viruses] 2023 Mar 24; Vol. 15 (4). Date of Electronic Publication: 2023 Mar 24.

SARS-CoV-2 Establishes a Productive Infection in Hepatoma and Glioblastoma Multiforme Cell Lines.

Autor: Smirnova OA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia., Ivanova ON; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia., Fedyakina IT; Gamaleya National Research Centre for Epidemiology and Microbiology of the Ministry of Russia, 123098 Moscow, Russia., Yusubalieva GM; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.; Federal Research and Clinical Center of Specialized Medical Care and Medical Technologies of the Federal Medical and Biological Agency of Russia, 115682 Moscow, Russia., Baklaushev VP; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.; Federal Research and Clinical Center of Specialized Medical Care and Medical Technologies of the Federal Medical and Biological Agency of Russia, 115682 Moscow, Russia., Yanvarev DV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia., Kechko OI; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia., Mitkevich VA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia., Vorobyev PO; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia., Fedorov VS; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia., Bartosch B; Lyon Cancer Research Center/INSERM U1052, 69008 Lyon, France., Valuev-Elliston VT; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia., Lipatova AL; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia., Ivanov AV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.

Publikováno v: Cancers [Cancers (Basel)] 2023 Jan 19; Vol. 15 (3). Date of Electronic Publication: 2023 Jan 19.