Zobrazeno 1 - 10 of 51 pro vyhledávání: '"GM Shearer"'
1
Changes in T-helper cell function in human immunodeficiency virus- infected children during didanosine therapy as a measure of antiretroviral activity
Autor: M Clerici, E Roilides, KM Butler, L DePalma, D Venzon, GM Shearer, PA Pizzo
Publikováno v: Blood. 80:2196-2202
Didanosine has shown activity against the human immunodeficiency virus (HIV) in both children and adults. We prospectively assessed T-helper cell (Th) function as determined by in vitro interleukin-2 (IL-2) production in response to a panel of T-cell
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3a2362e448e446423b6adc448f384ae9
https://doi.org/10.1182/blood.v80.9.2196.bloodjournal8092196
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2
Cerebrospinal fluid cytokines in pediatric neuropsychiatric disease
Autor: Bb, Mittleman, Francisco Castellanos, Lk, Jacobsen, Jl, Rapoport, Se, Swedo, Gm, Shearer
Publikováno v: Europe PubMed Central
This study examines cerebrospinal fluid from patients with three neuropsychiatric diseases of childhood for the presence and levels of several cytokines relevant to cell-mediated (type 1) and humoral (type 2) immunity. The patient groups include chil
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::16ae728466e0e7194090d27fdccfa005
https://pubmed.ncbi.nlm.nih.gov/9300724
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3
In vitro restoration of T cell immune function in human immunodeficiency virus-positive persons: effects of interleukin (IL)-12 and anti-IL-10
Autor: Al, Landay, Mario Clerici, Hashemi F, Kessler H, Ja, Berzofsky, Gm, Shearer
Publikováno v: Europe PubMed Central
Cells from human immunodeficiency virus (HIV)-positive patients were evaluated for their in vitro responsiveness to recall antigen, alloantigen, and phytohemagglutinin (PHA) following the in vitro addition of interleukin (IL)-12 or anti-IL-10. Three-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ecf54c0ca434d3c4ec684845888824c8
https://pubmed.ncbi.nlm.nih.gov/8627058
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4
Human immunodeficiency virus type 1 (HIV-1)-seronegative injection drug users at risk for HIV exposure have antibodies to HLA class I antigens and T cells specific for HIV envelope
Autor: Beretta A, Sh, Weiss, Rappocciolo G, Mayur R, De Santis C, Quirinale J, Antonio Cosma, Robbioni P, Gm, Shearer, Ja, Berzofsky
Publikováno v: Europe PubMed Central
The question of whether persistently seronegative persons at high risk for human immunodeficiency virus type 1 (HIV-1) infection exhibit HIV-1-specific T cell responses and antibodies to HIV-1 envelope epitopes shared with selected HLAs was assessed.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::088367658d758caa158d77bfffb8f51d
https://pubmed.ncbi.nlm.nih.gov/8699088
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5
Functional studies of epidermal Langerhans cells and blood monocytes in HIV-infected persons
Autor: Blauvelt A, Mario Clerici, Dr, Lucey, Sm, Steinberg, Yarchoan R, Walker R, Gm, Shearer, Si, Katz
Publikováno v: Europe PubMed Central
APC dysfunction may be important in immune dysregulation associated with HIV disease. Langerhans cells, epidermal APC, can be infected with HIV, although their function in HIV-infected persons has not been studied. Therefore, we studied the immunolog
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f1252e5c751db3c9858d21d4c4cef61b
https://pubmed.ncbi.nlm.nih.gov/7897231
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7
In vitro analysis of cell-mediated immunity: clinical relevance
Autor: Gm, Shearer, Mario Clerici
Publikováno v: Europe PubMed Central
Cellular immunity, a major component of the immune system, contributes to protection against infections and plays a role in the rejection of foreign allografts. T helper cells and the antigen-presenting cells with which they interact provide importan
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a90c7f6b3d39277d833de50fb0d60b15
https://pubmed.ncbi.nlm.nih.gov/7955403
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10
T cell-antigen-presenting cell interactions in human systemic lupus erythematosus. Evidence for heterogeneous expression of multiple defects
Autor: Cs, Via, Gc, Tsokos, Bermas B, Mario Clerici, Gm, Shearer
Publikováno v: Europe PubMed Central
To assess interactions between T cells and APC in patients with SLE, PBL were stimulated in vitro and IL-2 production measured after stimulation with either a MHC-self-restricted Ag (influenza A virus) or an Ag which can use both MHC-self-restricted
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e11b6141ce3170ba25069bef6cfca7c5
https://pubmed.ncbi.nlm.nih.gov/8376810
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