Zobrazeno 1 - 10
of 525
pro vyhledávání: '"GLUTAMATE TRANSPORTER 1"'
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 170, Iss , Pp 116102- (2024)
Brain ischemia is one of the leading causes of death and long-term disability worldwide. Cessation of the blood supply to the brain directly stimulates many pathological events, including glutamate overload and neuroinflammation. Glial cell activatio
Externí odkaz:
https://doaj.org/article/694f4ec9e12d4a0fab68a5aaab97bacf
Autor:
Yuan-Yuan Ji, Xin Liu, Xin Li, Yi-Fan Xiao, Teng Ma, Jian Wang, Yue Feng, Juan Shi, Mei-Qing Wang, Jin-Lian Li, Jiang-Hua Lai
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Occlusal disharmony has a negative impact on emotion. The mesencephalic trigeminal nucleus (Vme) neurons are the primary afferent nuclei that convey proprioceptive information from proprioceptors and low-threshold mechanoreceptors in the periodontal
Externí odkaz:
https://doaj.org/article/6cb7606827c344a48268cc7c6cfe2812
Autor:
Lidia Bravo, Patricia Mariscal, Meritxell Llorca-Torralba, Jose María López-Cepero, Juan Nacher, Esther Berrocoso
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Neuropathic pain is a debilitating chronic condition provoked by a lesion in the nervous system and it induces functional alterations to the noradrenergic locus coeruleus (LC), affecting distinct dimensions of pain, like sensorial hypersensitivity, p
Externí odkaz:
https://doaj.org/article/d6f51b17595641b28c91361b71211282
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
Accumulating evidence suggests that glutamate clearance plays a critical role in the pathophysiology and treatment of depression. Preclinical and clinical studies have demonstrated that ketamine provides an immediate and sustained antidepressant effe
Externí odkaz:
https://doaj.org/article/ddeb10f84a5c4a2e99c2f87472b5d9b6
Autor:
Gui-Ying Zan, Yu-Jun Wang, Xue-Ping Li, Jun-Fan Fang, Song-Yu Yao, Jun-Ying Du, Qian Wang, Xiang Sun, Rui Liu, Xiao-Mei Shao, Jian-Dong Long, Jing-Rui Chai, Ying-Zhi Deng, Ye-Qing Chen, Qing-Lin Li, Jian-Qiao Fang, Zhi-Qiang Liu, Jing-Gen Liu
Publikováno v:
Cell Reports, Vol 37, Iss 5, Pp 109913- (2021)
Summary: Opiates produce a strong rewarding effect, but abstinence from opiate use emerges with severe negative emotions. Depression is one of the most frequent emotion disorders associated with opiate abstinence, which is thought to be a main cause
Externí odkaz:
https://doaj.org/article/28a139f7693d43c18cec2da3add1381a
Autor:
Carla Cristina Miranda Castro, Sayonara Pereira Silva, Lívia Nascimento Rabelo, José Pablo Gonçalves Queiroz, Laura Damasceno Campos, Larissa Camila Silva, Felipe Porto Fiuza
Publikováno v:
Cells, Vol 11, Iss 24, p 4033 (2022)
Brain aging involves regional alterations of specific cellular subpopulations in the human hippocampus: a network hub for memory consolidation. The present study investigates whether age, sex, education years, and the concentration of neuropathologic
Externí odkaz:
https://doaj.org/article/2b7a4258a0ff4dd2a3427bafa95cd486
Autor:
Ajmal Nassar, Triveni Kodi, Sairaj Satarker, Prasada Chowdari Gurram, Dinesh Upadhya, Fayaz SM, Jayesh Mudgal, Madhavan Nampoothiri
Publikováno v:
Cells, Vol 11, Iss 24, p 4111 (2022)
Astrocytes are important for maintaining cholesterol metabolism, glutamate uptake, and neurotransmission. Indeed, inflammatory processes and neurodegeneration contribute to the altered morphology, gene expression, and function of astrocytes. Astrocyt
Externí odkaz:
https://doaj.org/article/4ae23b0f07174c92bcd2c4c55cef53d2
Akademický článek
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Akademický článek
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Publikováno v:
Basic and Clinical Neuroscience, Vol 10, Iss 4, Pp 345-354 (2019)
Introduction: Clavulanic acid (CLAV) is structurally similar to ceftriaxone, a potent stimulator of glial GlutamateTransporter-1 (GLT-1) expression. The present study aims at exploring the anti-nociceptive effects of CLAV, a beta-lactamase inhibitor
Externí odkaz:
https://doaj.org/article/04a613bf6aaf4497851a9d7455cdf0b0