Zobrazeno 1 - 10
of 76 684
pro vyhledávání: '"GLUTAMATE RECEPTOR"'
Autor:
Rajaram Kshetri, James O. Beavers, Romana Hyde, Roseline Ewa, Amber Schwertman, Sarahi Porcayo, Ben D. Richardson
Publikováno v:
Molecular Autism, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Background SHANK3, a gene encoding a synaptic scaffolding protein, is implicated in autism spectrum disorder (ASD) and is disrupted in Phelan-McDermid syndrome (PMS). Despite evidence of regression or worsening of ASD-like symptoms in indivi
Externí odkaz:
https://doaj.org/article/6dab4f94e5984fe6a60755ae9eb37ef6
Publikováno v:
Horticultural Plant Journal, Vol 10, Iss 6, Pp 1449-1462 (2024)
Poplar is one of the fastest-growing temperate trees in the world and is widely used in ornamental horticulture for shade. The root is essential for tree growth and development and its utilization potential is huge. Calcium (Ca), as a signaling molec
Externí odkaz:
https://doaj.org/article/441b1e66762f4e4d9664c8a82f99d955
Publikováno v:
Behavioral and Brain Functions, Vol 20, Iss 1, Pp 1-14 (2024)
Abstract Background Nicotine dependence is associated with glutamatergic neurotransmission in the caudate and putamen (CPu) of the forebrain which includes alterations in the structure of dendritic spines at glutamate synapses. These changes after ni
Externí odkaz:
https://doaj.org/article/a0932f9c6c46412ab65cb29a4ca110c1
Publikováno v:
Living with Mild Cognitive Impairment : A Guide to Maximizing Brain Health and Reducing the Risk of Dementia, 2024.
Externí odkaz:
https://doi.org/10.1093/oso/9780197749340.003.0021
Autor:
Serena Notartomaso, Nico Antenucci, Mariacristina Mazzitelli, Xavier Rovira, Serena Boccella, Flavia Ricciardi, Francesca Liberatore, Xavier Gomez-Santacana, Tiziana Imbriglio, Milena Cannella, Charleine Zussy, Livio Luongo, Sabatino Maione, Cyril Goudet, Giuseppe Battaglia, Amadeu Llebaria, Ferdinando Nicoletti, Volker Neugebauer
Publikováno v:
eLife, Vol 13 (2024)
We used light-sensitive drugs to identify the brain region-specific role of mGlu5 metabotropic glutamate receptors in the control of pain. Optical activation of systemic JF-NP-26, a caged, normally inactive, negative allosteric modulator (NAM) of mGl
Externí odkaz:
https://doaj.org/article/7992b22d74894ac98d325b25e79626e5
Autor:
Jingqi He, Jinguang Li, Yisen Wei, Zhangyin He, Junyu Liu, Ning Yuan, Risheng Zhou, Xingtao He, Honghong Ren, Lin Gu, Yanhui Liao, Xiaogang Chen, Jinsong Tang
Publikováno v:
BMC Psychiatry, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Glutamatergic function abnormalities have been implicated in the etiology of treatment-resistant schizophrenia (TRS), and the efficacy of clozapine may be attributed to its impact on the glutamate system. Recently, evidence has em
Externí odkaz:
https://doaj.org/article/49563322fe4a4051a83dc7786efde292
Publikováno v:
운동과학, Vol 33, Iss 1, Pp 46-55 (2024)
PURPOSE The first aim of this study is to change autistic behavior in Shank3B Knock-Out (KO) mice through treadmill exercise (TD), and the second aim is to alter SHANK protein receptors in the prefrontal cortex (PFC) of mice through TD. METHODS Male
Externí odkaz:
https://doaj.org/article/b01c64778d8643e6ab19267bd7f8fb9d
Autor:
A. F. M. Towheedur Rahman, Sarojini Bulbule, Jawad Bin Belayet, Anna Benko, Carl Gunnar Gottschalk, David N. Frick, Leggy A. Arnold, M. Mahmun Hossain, Avik Roy
Publikováno v:
Cells, Vol 13, Iss 23, p 1964 (2024)
Enhancement of neuronal plasticity by small-molecule therapeutics protects cognitive skills and also ameliorates progressive neurodegenerative pathologies like Alzheimer’s disease (AD) and dementia. One such compound, a novel histone deacetylase 2
Externí odkaz:
https://doaj.org/article/f35163f94a3b4050ae9b78605e35cd35
Publikováno v:
In Computers in Biology and Medicine September 2024 179