Zobrazeno 1 - 10
of 1 556
pro vyhledávání: '"GLUT4, glucose transporter type 4"'
Autor:
Lee, Eunbi1 (AUTHOR) 21eunbi@naver.com, Nam, Ju-Ock1,2 (AUTHOR) namjo@knu.ac.kr
Publikováno v:
International Journal of Molecular Sciences. May2024, Vol. 25 Issue 9, p4908. 16p.
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2749-2767 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2749-2767 (2021)
Diabetic nephropathy (DN) has been recognized as a severe complication of diabetes mellitus and a dominant pathogeny of end-stage kidney disease, which causes serious health problems and great financial burden to human society worldwide. Conventional
Publikováno v:
Russian Journal of Bioorganic Chemistry; Aug2024, Vol. 50 Issue 4, p1263-1284, 22p
Autor:
Qiong Wang, Sigurdur Trausti Karvelsson, Aristotelis Kotronoulas, Thorarinn Gudjonsson, Skarphedinn Halldorsson, Ottar Rolfsson
Publikováno v:
Molecular & Cellular Proteomics : MCP
Breast cancer cells that have undergone partial epithelial–mesenchymal transition (EMT) are believed to be more invasive than cells that have completed EMT. To study metabolic reprogramming in different mesenchymal states, we analyzed protein expre
Autor:
Daniel J. Horan, Hyun Cheol Roh, Aaron C. Ericsson, Surabhi D. Abhyankar, Natalie D. Stull, Xiaocheng C. Dong, Alexander G. Robling, Hongxia Ren, Robert N. Bone, Austin M. Reilly, Shijun Yan, Jason M. Conley, Carmella Evans-Molina, Menghao Huang
Publikováno v:
The Journal of Biological Chemistry
Insulin resistance impairs postprandial glucose uptake through glucose transporter type 4 (GLUT4) and is the primary defect preceding type 2 diabetes. We previously generated an insulin-resistant mouse model with human GLUT4 promoter-driven insulin r
Publikováno v:
Redox Biology, Vol 12, Iss, Pp 82-102 (2017)
Redox Biology
Redox Biology
Metabolic diseases such as type 2 diabetes are a major public health issue worldwide. These diseases are often linked to a dysfunctional adipose tissue. Fat is a large, heterogenic, pleiotropic and rather complex tissue. It is found in virtually all
Autor:
Punniyakoti Veeraveedu Thanikachalam, Pooja Chawla, Rahul K. Maurya, Srinivasan Ramamurthy, Garima Bansal
Publikováno v:
Journal of Advanced Research, Vol 23, Iss, Pp 163-205 (2020)
Journal of Advanced Research
Journal of Advanced Research
Graphical abstract
Highlights • TZDs, an important pharmacophore in the treatment of diabetes. • Various analog-based synthetic strategies and biological significance are discussed. • Clinical studies using TZDs along with other antidiabet
Highlights • TZDs, an important pharmacophore in the treatment of diabetes. • Various analog-based synthetic strategies and biological significance are discussed. • Clinical studies using TZDs along with other antidiabet
Publikováno v:
Stem Cell Research
Stem Cell Research, Vol 38, Iss, Pp-(2019)
Stem Cell Research, Vol 38, Iss, Pp-(2019)
Myocardial infarction is the most prevalent of cardiovascular diseases and pharmacological interventions do not lead to restoration of the lost cardiomyocytes. Despite extensive stem cell therapy studies, clinical trials using cardiac progenitor cell
Autor:
Aierken, Aili1 (AUTHOR), Li, Balun1 (AUTHOR), Liu, Peng2 (AUTHOR), Cheng, Xuedi1 (AUTHOR), Kou, Zheng1 (AUTHOR), Tan, Ning1 (AUTHOR), Zhang, Mengfei1 (AUTHOR), Yu, Shuai1 (AUTHOR), Shen, Qiaoyan1 (AUTHOR), Du, Xiaomin1 (AUTHOR), Enkhbaatar, Bold Bayar1 (AUTHOR), Zhang, Juqing1 (AUTHOR), Zhang, Rui1 (AUTHOR), Wu, Xiaolong1 (AUTHOR), Wang, Ruibin1 (AUTHOR), He, Xin1 (AUTHOR), Li, Na1 (AUTHOR), Peng, Sha1 (AUTHOR), Jia, Wenwen3 (AUTHOR) wuj3@tongji.edu.cn, Wang, Congrong4 (AUTHOR) crwang@tongji.edu.cn
Publikováno v:
Stem Cell Research & Therapy. 4/12/2022, Vol. 13 Issue 1, p1-15. 15p.
Publikováno v:
Bioscience Reports
Bioscience Reports, Vol 32, Iss 4 (2012)
Bioscience Reports, Vol 32, Iss 4 (2012)
Intracellular membrane trafficking along endocytic and secretory transport pathways plays a critical role in diverse cellular functions including both developmental and pathological processes. Briefly, proteins and lipids destined for transport to di