Zobrazeno 1 - 10
of 18
pro vyhledávání: '"GLENN S. ELLIOTT"'
Autor:
Werner Mellert, M I Banton, Linda A. Malley, Glenn S. Elliott, Gerald L. Kennedy, Theodore W. Slone, R J Parod, K Deckardt, B Hildebrand, K. Küttler, J C Griffiths
Publikováno v:
Drug and Chemical Toxicology. 24:315-338
A two-year feeding study in rats and an 18-month feeding study in mice were conducted to evaluate the potential chronic toxicity and oncogenicity of NMP in Crl:CD (SD)BR rats and B6C3F1/CrlBR mice. Groups of 62 male and female rats were administered
Publikováno v:
Drug and Chemical Toxicology. 24:75-86
Pentane (CAS No. 109-66-0) is a chemical being used as a co-solvent in a polymer production facility with potential for inhalation exposure in humans. To assess the toxicity of pentane, groups of 10 male rats each were exposed by inhalation, 6 hr/day
Publikováno v:
Toxicological Sciences. 56:414-423
Groups of 25 female F344 rats and 25 female B6C3F1 mice were exposed to 0, 30, 300, 600, or 1200 ppm tetrafluoroethylene (TFE) by inhalation for up to 12 days. Another set of 25 female rats and 25 female mice of the same strains were given 0, 5, 20,
Publikováno v:
Drug and Chemical Toxicology. 22:435-454
Cyclododecatriene (CDDT, CAS No. 4904-61-4) was tested for its inhalation toxicity in rats following repeated exposures. Male rats were exposed nose-only to CDDT for 6 hr/day, 5 days/wk for a total of 9 exposures over 2 weeks. Particular attention wa
Publikováno v:
Toxicology. 126:137-152
A previous study ( Ladics et al., 1995 ) conducted in our laboratory using the known immunosuppressant agent, cyclophosphamide, indicated that a functional assay for assessment of humoral immunity may be conducted in rats in a standard toxicology stu
Autor:
Jon C. Cook, Ellen K. Silbergeld, Carolyn S. Van Pelt, Glenn S. Elliott, John C. O'Connor, Lisa B. Biegel, Jodi A. Flaws, Gregory S. Ladics, Steven R. Frame, Mark E. Hurtt, Anne N. Hirshfield
Publikováno v:
Toxicological Sciences. 44:116-142
Over the past several years, there has been increasing concern that chemicals and pesticides found in the environment may mimic endogenous estrogens, potentially producing adverse effects in wildlife and human populations. Because estrogenicity is on
Autor:
Glenn S. Elliott, George M. Rusch, Steven R. Frame, Linda A. Malley, Karin S. Bentley, Henry J. Trochimowicz, William J. Brock
Publikováno v:
Drug and Chemical Toxicology. 21:417-447
The chronic toxicity, oncogenicity, and mutagenicity of chlorotetrafluoroethane (HCFC-124) were evaluated. In the chronic toxicity/oncogenicity study, male and female rats were exposed to 0, 2000, 10,000, or 50,000 ppm HCFC-124 for 6 hr/day, 5 days/w
Autor:
Stephen R. Frame, Glenn S. Elliott, Jon C. Cook, John D. Obourn, Lisa B. Biegel, Mark E. Hurtt
Publikováno v:
Drug and Chemical Toxicology. 20:1-10
A two-year mechanistic bioassay in male Crl:CD BR rats was initiated with 50 ppm Wyeth-14,643 (WY) to investigate the relationship between peroxisome proliferating compounds and Leydig cell adenoma formation. After 154 days, the survival rate in the
Autor:
A. S. Panepinto, Steven R. Frame, Judith C. Stadler, C. Bevan, J. K. Baldwin, Hon-Wing Leung, E. Moran, Glenn S. Elliott
Publikováno v:
Fundamental and Applied Toxicology. 32:1-10
This study was conducted to evaluate the subchronic toxicity of 4-vinylcyclohexene (VCH). Male and female Sprague–Dawley rats and B6C3F 1 mice were exposed by inhalation to VCH 6 hr/day, 5 days/week for 13 weeks. Rats were exposed to 0, 250, 1000,
Autor:
LINDA ANGEVINE MALLEY, THEODORE W. SLONE, G. TRACY MAKOVEC, GLENN S. ELLIOTT, GERALD L. KENNEDY
Publikováno v:
Toxicological Sciences. 28:80-93