Zobrazeno 1 - 10
of 261
pro vyhledávání: '"GL261"'
Autor:
Alberto Reale, Andrea Gatta, Amruth Kaleem Basha Shaik, Mariam Shallak, Anna Maria Chiaravalli, Michele Cerati, Martina Zaccaria, Stefano La Rosa, Arianna Calistri, Roberto Sergio Accolla, Greta Forlani
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background Glioblastoma (GBM) is the most frequent and aggressive brain tumor in adults with the lowest survival rates five years post-diagnosis. Oncolytic viruses (OVs) selectively target and damage cancer cells, and for this reason they ar
Externí odkaz:
https://doaj.org/article/d38e76a70e96482885d5a575874d5519
Publikováno v:
Cancers, Vol 16, Iss 11, p 1997 (2024)
Glioblastoma (GBM) is the most aggressive brain cancer. To model GBM in research, orthotopic brain tumor models, including syngeneic models like GL261 and genetically engineered mouse models like TRP, are used. In longitudinal studies, tumor growth a
Externí odkaz:
https://doaj.org/article/ceeeda5e0dd84fdcb3c1c1d3d0bf0196
Autor:
Rheal A. Towner, Nataliya Smith, Debra Saunders, Megan Lerner, Randy L. Jensen, James Battiste, Marya Ahmed, Jonathan D. Wren
Publikováno v:
Neuroglia, Vol 4, Iss 1, Pp 69-86 (2023)
We previously reported on the experimental validation of several in silico-predicted glioma biomarkers (e.g., Plexin-B2 (PLXNB2), SLIT3, and Spondin-1 (SPON1)) that were found to be higher in human high-grade gliomas (HGGs). In this study, we validat
Externí odkaz:
https://doaj.org/article/e113949dfcc24138b91cd746e410f5c7
Autor:
Tikhon S. Redkin, Ekaterina E. Sleptsova, Victoria D. Turubanova, Mariia O. Saviuk, Svetlana A. Lermontova, Larisa G. Klapshina, Nina N. Peskova, Irina V. Balalaeva, Olga Krysko, Tatiana A. Mishchenko, Maria V. Vedunova, Dmitri V. Krysko
Publikováno v:
Pharmaceutics, Vol 15, Iss 10, p 2430 (2023)
Research in the past decade on immunogenic cell death (ICD) has shown that the immunogenicity of dying tumor cells is crucial for effective anticancer therapy. ICD induction leads to the emission of specific damage-associated molecular patterns (DAMP
Externí odkaz:
https://doaj.org/article/314193d9eefd4e6b8210e90a43c89af4
Akademický článek
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Publikováno v:
Jichu yixue yu linchuang, Vol 41, Iss 7, Pp 957-962 (2021)
Objective To investigate the effects of carboxyamidotriazole-orotate (CTO) on the proliferation and apoptosis of mouse glioma cell line GL261. Methods The proliferation of GL261 cells was detected by live cell counting. Cell cycle of GL261 cells was
Externí odkaz:
https://doaj.org/article/574ad4d1ab794f1898521c165e9ec4e9
Autor:
Mathilde Bausart, Elia Bozzato, Nicolas Joudiou, Xanthippi Koutsoumpou, Bella Manshian, Véronique Préat, Bernard Gallez
Publikováno v:
Cancers, Vol 15, Iss 6, p 1919 (2023)
Orthotopic glioblastoma xenografts are paramount for evaluating the effect of innovative anti-cancer treatments. In longitudinal studies, tumor growth (or regression) of glioblastoma can only be monitored by noninvasive imaging. For this purpose, bio
Externí odkaz:
https://doaj.org/article/eb09aeb2cb4e4c7db1dfd2938830f092
Multimodal treatment adding immunotherapy and photodynamic treatment (PDT) to standard therapy might improve the devastating therapeutic outcome of glioblastoma multiforme patients. As a first step, we provide investigations to optimize dendritic cel
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A87051
https://ul.qucosa.de/api/qucosa%3A87051/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A87051/attachment/ATT-0/
Autor:
Marta Lopes, Joana Vieira de Castro, Marta Pojo, Céline S. Gonçalves, Eduarda P. Martins, Bárbara Coimbra, Ioannis Sotiropoulos, Nuno Sousa, Ana João Rodrigues, Bruno M. Costa
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The existence of a clear association between stress and cancer is still a matter of debate. Recent studies suggest that chronic stress is associated with some cancer types and may influence tumor initiation and patient prognosis, but its role in brai
Externí odkaz:
https://doaj.org/article/6aa6260002fb44b484643f2a66a3ffbb
Autor:
Mohammed H. Ahmed, Isaias Hernández-Verdin, Emie Quissac, Nolwenn Lemaire, Coralie Guerin, Lea Guyonnet, Noël Zahr, Laura Mouton, Mathieu Santin, Alexandra Petiet, Charlotte Schmitt, Guillaume Bouchoux, Michael Canney, Marc Sanson, Maïté Verreault, Alexandre Carpentier, Ahmed Idbaih
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 455 (2023)
Therapeutic antibodies targeting immune checkpoints have shown limited efficacy in clinical trials in glioblastoma (GBM) patients. Ultrasound-mediated blood–brain barrier opening (UMBO) using low-intensity pulsed ultrasound improved drug delivery t
Externí odkaz:
https://doaj.org/article/6214fb5f9f334bc28d5749b082bc56c0