Zobrazeno 1 - 10
of 84
pro vyhledávání: '"GJVM, Van Osch"'
Autor:
C Voskamp, LA Anderson, WJLM Koevoet, S Barnhoorn, PG Mastroberardino, GJVM van Osch, R Narcisi
Publikováno v:
European Cells & Materials, Vol 42, Pp 401-414 (2021)
Mesenchymal stem cells (MSCs) are promising cells for regenerative medicine therapies because they can differentiate towards multiple cell lineages. However, the occurrence of cellular senescence and the acquiring of the senescence-associated secreto
Externí odkaz:
https://doaj.org/article/b24bd650f1c143828171c2dfd52711ad
Autor:
S Khatab, GJVM van Osch, N Kops, YM Bastiaansen-Jenniskens, PK Bos, JAN Verhaar, MR Bernsen, GM van Buul
Publikováno v:
European Cells & Materials, Vol 36, Pp 218-230 (2018)
Mesenchymal stem cells (MSCs) represent a promising biological therapeutic option as an osteoarthritis (OA)-modifying treatment. MSCs secrete factors that can counteract inflammatory and catabolic processes and attract endogenous repair cells. The ef
Externí odkaz:
https://doaj.org/article/f33b6103552743f9ad5f879cca2bc49d
Publikováno v:
European Cells & Materials, Vol 35, Pp 242-254 (2018)
he aim of the current study was to reduce the clinically used supra-physiological dose of bone morphogenetic protein-2 (BMP-2) (usually 1.5 mg/mL), which carries the risk of adverse events, by using a more effective release system. A slow release sys
Externí odkaz:
https://doaj.org/article/91244257ec3c4a5798c45bca073d1331
Autor:
MJC Leijs, E Villafuertes, JC Haeck, WJLM Koevoet, B Fernandez-Gutierrez, MJ Hoogduijn, JAN Verhaar, MR Bernsen, GM van Buul, GJVM van Osch
Publikováno v:
European Cells & Materials, Vol 33, Pp 43-58 (2017)
Bone marrow derived mesenchymal stem cells (MSCs) have immunomodulatory and trophic capacities. For therapeutic application in local chronic inflammatory diseases, MSCs, preferably of allogeneic origin, have to retain immunomodulatory properties. Thi
Externí odkaz:
https://doaj.org/article/31fb1f1c61e34c25b29424e6083a3f4b
Autor:
W Wei, R Rudjito, N Fahy, JAN Verhaar, S Clockaerts, YM Bastiaansen-Jenniskens, GJVM van Osch
Publikováno v:
European Cells & Materials, Vol 30, Pp 303-314 (2015)
Cartilage repair by bone marrow derived mesenchymal stem cells (MSCs) can be influenced by inflammation in the knee. Next to synovium, the infrapatellar fat pad (IPFP) has been described as a source for inflammatory factors. Here, we investigated whe
Externí odkaz:
https://doaj.org/article/027cb65d751f469398bb8dce6116ab5f
Publikováno v:
European Cells & Materials, Vol 27, Pp 350-364 (2014)
In the context of skeletal tissue development and repair, endochondral ossification has inspired a new approach to regenerate bone tissue in vivo using a cartilage intermediate as an osteoinductive template. The aim of this study was to investigate t
Externí odkaz:
https://doaj.org/article/ba4d0bfd0b044c2b91e96187b2ea5cb7
Publikováno v:
European Cells & Materials, Vol 27, Pp 264-280 (2014)
Cartilage has limited self-regenerative capacity. Tissue engineering can offer promising solutions for reconstruction of missing or damaged cartilage. A major challenge herein is to define an appropriate cell source that is capable of generating a st
Externí odkaz:
https://doaj.org/article/093d9ed0aeba41cc8c02ea03c325e062
Autor:
ML de Vries-van Melle, MS Tihaya, N Kops, WJLM Koevoet, JM Murphy, JAN Verhaar, M Alini, D Eglin, GJVM van Osch
Publikováno v:
European Cells & Materials, Vol 27, Pp 112-123 (2014)
Hydrogels pose interesting features for cartilage regeneration strategies, such as the option for injectability and in situ gelation resulting in optimal filling of defects. We aimed to study different hydrogels for their capability to support chondr
Externí odkaz:
https://doaj.org/article/b91e3e32097840dc98fcf948077da3f1
Publikováno v:
European Cells & Materials, Vol 26, Pp 80-90 (2013)
Mediators in the synovial fluid are thought to play a major role in osteoarthritic cartilage turnover. The purpose of the current study was to investigate the role of oncostatin M (OSM) in osteoarthritis (OA) by evaluating the presence of the cytokin
Externí odkaz:
https://doaj.org/article/3c8e7c96fa4041d4994fbb810388efd9
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.