Better maintained adherence on switching from twice-daily to once-daily therapy for HIV: a 24-week randomized trial of treatment simplification using stavudine prolonged-release capsules

Autor: J Osorio, SD Portsmouth, Brian Gazzard, GJ Moyle, K McCormick

Publikováno v: HIV Medicine. 6:185-190

Background Adherence to antiretroviral therapy is critical to treatment outcomes. Adherence studies in other therapeutic areas of medicine suggest that once-daily regimens support improved adherence when compared to twice-daily therapy. An expansion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eb5798e609e1d40270bf5aef98ca889
https://doi.org/10.1111/j.1468-1293.2005.00287.x

Viral resistance patterns selected by antiretroviral drugs and their potential to guide treatment choice

Autor: GJ Moyle

Publikováno v: Expert opinion on investigational drugs. 6(8)

Massive viral turnover and reverse transcriptase's high error rate create the potential for drug-resistant viral variants to appear rapidly under the selective pressure of antiretroviral therapy. Loss of antiviral effect in treatment-adherent persons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b41f902210402e682c8eef7e86c505f4
https://pubmed.ncbi.nlm.nih.gov/15989655

Individualisation of HIV therapy: the clinician's perspective

Autor: BG Gazzard, GJ Moyle

Publikováno v: The British journal of clinical practice. 49(3)

Assessment of clinical and laboratory markers of HIV infection may be used to individualise antiretroviral therapy. Data suggest that measures of viral load may be of considerable value as both a baseline and dynamic therapy marker, making these tool

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5ad9687225c64229e94060b0e758018
https://pubmed.ncbi.nlm.nih.gov/7779666

A Comparison of Self-reported Pain Measures Between Sensory Phenotypes in HIV-associated Sensory Neuropathy.

Autor: Kemp HI; Pain Research Group, Imperial College London, London, UK. Electronic address: h.kemp@imperial.ac.uk., Vollert J; Pain Research Group, Imperial College London, London, UK; Division of Neurological Pain Research and Therapy, Department of Neurology, University Hospital of Schleswig-Holstein, Campus Kiel, Germany; Department of Anaesthesiology, Intensive Care and Pain Medicine, University Hospital Muenster, Germany; Neurophysiology, Mannheim Center of Translational Neuroscience (MCTN), Medical Faculty Mannheim, Heidelberg University, Germany., Davies NWS; Department of Neurology, Chelsea & Westminster NHS Foundation Trust, London, UK., Moyle GJ; Department of HIV Medicine, Chelsea & Westminster NHS Foundation Trust, London, UK., Rice ASC; Pain Research Group, Imperial College London, London, UK.

Publikováno v: The journal of pain [J Pain] 2023 Jan; Vol. 24 (1), pp. 112-127. Date of Electronic Publication: 2022 Sep 16.

Changes in bone mineral density after 96 weeks of treatment with atazanavir/ritonavir or lopinavir/ritonavir plus tenofovir DF/emtricitabine in treatment-naive patients with HIV-1 infection: the CASTLE body composition substudy.

Autor: Moyle GJ; Chelsea and Westminster Hospital, London, United Kingdom; †Research and Development, Bristol-Myers Squibb, Plainsboro, NJ; ‡Bristol-Myers Squibb, Wallingford, CT; and §Dupont Circle Physicians Group, Washington, DC., Hardy H, Farajallah A, McGrath SJ, Kaplita S, Ward D

Publikováno v: Journal of acquired immune deficiency syndromes (1999) [J Acquir Immune Defic Syndr] 2015 Jan 01; Vol. 68 (1), pp. 40-5.