Zobrazeno 1 - 10
of 777
pro vyhledávání: '"GITR"'
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Anuja Sathe, Carlos Ayala, Xiangqi Bai, Susan M. Grimes, Byrne Lee, Cindy Kin, Andrew Shelton, George Poultsides, Hanlee P. Ji
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-25 (2023)
Abstract Background Understanding the mechanistic effects of novel immunotherapy agents is critical to improving their successful clinical translation. These effects need to be studied in preclinical models that maintain the heterogenous tumor microe
Externí odkaz:
https://doaj.org/article/8cfb40beda144e8e8bef760c00d5144c
Publikováno v:
FEBS Open Bio, Vol 12, Iss 8, Pp 1542-1557 (2022)
Glucocorticoid‐induced TNF receptor‐related (GITR) can act as a co‐stimulatory receptor, representing a potential target for safely enhancing immunotherapy efficacy. GITR is triggered by a GITR ligand or an agonist antibody and activates CD8+ a
Externí odkaz:
https://doaj.org/article/18c31dff14264b6bb4e923947ba750a3
Autor:
Caixu Pan, Qinchuan Wu, Shuai Wang, Zhibin Mei, Lele Zhang, Xingxing Gao, Junjie Qian, Zhentian Xu, Ke Zhang, Rong Su, Danjing Guo, Lin Zhou, Shusen Zheng
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
The glucocorticoid-induced tumor necrosis factor receptor (GITR) agonistic antibody (DTA-1) has been proved to elicit robust immune response in various kinds of tumors. However, only a few of the HCC patients could benefit from it, and the mechanism
Externí odkaz:
https://doaj.org/article/59c55d5eed5545d1a162ec5624ba1fda
Autor:
Dalila Mele, Greta Pessino, Giuseppe Trisolini, Alberto Luchena, Marco Benazzo, Patrizia Morbini, Stefania Mantovani, Barbara Oliviero, Mario U. Mondelli, Stefania Varchetta
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Natural killer (NK) cells are emerging as unique players in the immune response against cancer; however, only limited data are available on tumor infiltrating NK cells in head and neck squamous cell carcinoma (HNSCC), one of the most common cancer. O
Externí odkaz:
https://doaj.org/article/d70106eab97546b0ba573cc4777af767
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Hodaka Nagai, Mitsuki Azuma, Ayaka Sato, Nagito Shibui, Sayaka Ogawara, Yuta Tsutsui, Ayano Suzuki, Tomomi Wakaizumi, Aya Ito, Shimpei Matsuyama, Masashi Morita, Mari Hikosaka Kuniishi, Naoto Ishii, Takanori So
Publikováno v:
Cells, Vol 12, Iss 12, p 1596 (2023)
The costimulatory signal regulated by the members of the tumor necrosis factor receptor (TNFR) superfamily expressed by T cells plays essential roles for T cell responses and has emerged as a promising target for cancer immunotherapy. However, it is
Externí odkaz:
https://doaj.org/article/80dc16e5ab2f4e0cb885ec6c907ff8fd
Autor:
Bernardo L. Rapoport, Helen C. Steel, Nomsa Hlatshwayo, Annette J. Theron, Pieter W. A. Meyer, Simon Nayler, Carol-Ann Benn, Teresa Smit, Luyanda L. I. Kwofie, Liezl Heyman, Ronald Anderson
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Breast cancer cells exploit the up-regulation or down-regulation of immune checkpoint proteins to evade anti-tumor immune responses. To explore the possible involvement of this mechanism in promoting systemic immunosuppression, the pre-treatment leve
Externí odkaz:
https://doaj.org/article/86487d26257341118fa96a706e3a33f4
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Nuclear Materials and Energy, Vol 29, Iss , Pp 101077- (2021)
The formation of microscopic cone-like structures on a Cr surface is observed under He plasma exposure at a low incident ion energy of ∼106 eV in the PISCES-A linear plasma device. 2D emission profiles of the Cr I line intensity, measured with a hy
Externí odkaz:
https://doaj.org/article/c153f6aa16fa4d10ad7359b0e7ef7bbe