Zobrazeno 1 - 10
of 112
pro vyhledávání: '"GIRIJA G. KONDURI"'
Publikováno v:
Physiological Reports, Vol 12, Iss 1, Pp n/a-n/a (2024)
Abstract Mechanisms underlying hyperoxia‐induced airflow restriction in the pediatric lung disease Bronchopulmonary dysplasia (BPD) are unclear. We hypothesized a role for Renin‐Angiotensin System (RAS) activity in BPD. RAS is comprised of a pro
Externí odkaz:
https://doaj.org/article/86373901d64e4430b5042dfb6b198bc1
Autor:
Karl W. Doerfer, Tara Sander, Girija G. Konduri, David R. Friedland, Joseph E. Kerschner, Christina L. Runge
Publikováno v:
Laryngoscope Investigative Otolaryngology, Vol 5, Iss 3, Pp 497-505 (2020)
Abstract Objectives To evaluate the efficiency of in‐house genetic testing for mutations causing the most common types of inherited, nonsyndromic, sensorineural hearing loss (SNHL). Methods Retrospective cohort study of 200 patients at a single, pe
Externí odkaz:
https://doaj.org/article/9f86467096fd41e7bec1a669bc818a23
Publikováno v:
Physiological Reports, Vol 8, Iss 18, Pp n/a-n/a (2020)
Abstract We investigated the hypothesis that exposure of lungs at the saccular stage of development to hyperoxia leads to persistent growth arrest and dysfunction of 5’AMP‐activated protein kinase (AMPK), a key energy sensor in the cell. We expos
Externí odkaz:
https://doaj.org/article/d30ced049973427c83866079895be877
Autor:
Ahmed Elsaie, Renuka T. Menon, Amrit K. Shrestha, Sharada H. Gowda, Nidhy P. Varghese, Roberto J. Barrios, Cynthia L. Blanco, Girija G. Konduri, Binoy Shivanna
Publikováno v:
Antioxidants, Vol 10, Iss 12, p 1913 (2021)
Bronchopulmonary dysplasia and pulmonary hypertension, or BPD-PH, are serious chronic lung disorders of prematurity, without curative therapies. Hyperoxia, a known causative factor of BPD-PH, activates adenosine monophosphate-activated protein kinase
Externí odkaz:
https://doaj.org/article/0f8ef29ee28045e4ba30c4d3255d0549
Autor:
REYHANEH SEPEHR, SAID H. AUDI, SEPIDEH MALEKI, KEVIN STANISZEWSKI, ANNIE L. EIS, GIRIJA G. KONDURI, MAHSA RANJI
Publikováno v:
Journal of Innovative Optical Health Sciences, Vol 6, Iss 3, Pp 1350017-1-1350017-10 (2013)
Reactive oxygen species (ROS) have been implicated in the pathogenesis of many acute and chronic pulmonary disorders such as acute lung injury (ALI) in adults and bronchopulmonary dysplasia (BPD) in premature infants. Bacterial infection and oxygen t
Externí odkaz:
https://doaj.org/article/2c8163fd9f094d56a37e84f03f38400b
Autor:
Paul Sidlowski, Amanda Czerwinski, Yong Liu, Pengyuan Liu, Ru-Jeng Teng, Suresh Kumar, Clive Wells, Kirkwood Pritchard, Girija G. Konduri, Adeleye J. Afolayan
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 68:395-405
Mitochondrial function and metabolic homeostasis are integral to cardiovascular function and influence how vascular cells respond to stress. However, little is known regarding how mitochondrial redox control mechanisms and metabolic regulation intera
Autor:
Ru-Jeng Teng, Girija G. Konduri, Ujala Rana, Adeleye J. Afolayan, Abdul K. Parchur, Megha Sharma, Chintamani Joshi, Amit Joshi, Teresa Michalkiewicz
Publikováno v:
Am J Respir Cell Mol Biol
Impaired angiogenesis function in pulmonary artery endothelial cells (PAEC) contributes to persistent pulmonary hypertension of the newborn (PPHN). Decreased nitric oxide (NO) amounts in PPHN lead to impaired mitochondrial biogenesis and angiogenesis
Autor:
Xigang Jing, Dustin P. Martin, Ru-Jeng Teng, Stephen Naylor, Girija G. Konduri, Neil Hogg, Billy W. Day, Kirkwood A. Pritchard, Aaron Haefke
Publikováno v:
Free Radic Biol Med
Bronchopulmonary dysplasia (BPD) is caused primarily by oxidative stress and inflammation. To induce BPD, neonatal rat pups were raised in hyperoxic (>90% O2) environments from day one (P1) until day ten (P10) and treated with N-acetyl-lysyltyrosylcy
Autor:
Abdul K. Parchur, Brianna Entringer, Teresa Michalkiewicz, Girija G. Konduri, Ru-Jeng Teng, Amit Joshi, Ujala Rana, Emily Callan
Publikováno v:
Am J Respir Cell Mol Biol
Decreased angiogenesis contributes to persistent pulmonary hypertension of the newborn (PPHN); mechanisms remain unclear. AMPK (5′AMP activated protein kinase) is a key regulator of cell metabolism. We investigated the hypothesis that a decrease in
Autor:
Renuka T. Menon, Amrit Kumar Shrestha, Sharada H. Gowda, Binoy Shivanna, Girija G. Konduri, Nidhy P. Varghese, Cynthia L. Blanco, Roberto Barrios, Ahmed El-Saie
Publikováno v:
Antioxidants
Antioxidants, Vol 10, Iss 1913, p 1913 (2021)
Antioxidants; Volume 10; Issue 12; Pages: 1913
Antioxidants, Vol 10, Iss 1913, p 1913 (2021)
Antioxidants; Volume 10; Issue 12; Pages: 1913
Bronchopulmonary dysplasia and pulmonary hypertension, or BPD-PH, are serious chronic lung disorders of prematurity, without curative therapies. Hyperoxia, a known causative factor of BPD-PH, activates adenosine monophosphate-activated protein kinase