Výsledky vyhledávání - "GILCHREST, B.A."

Akademický článek

Bone morphogenetic protein (BMP) signaling controls hair pigmentation by means of cross-talk with the melanocortin receptor-1 pathway

Autor: Sharov, A.A., Fessing, Michael Y., Atoyan, R., Sharova, T.Y., Haskell-Luevano, C., Weiner, L., Funa, K., Brissette, J.L., Gilchrest, B.A., Botchkarev, Vladimir A.

Hair pigmentation is controlled by tightly coordinated programs of melanin synthesis and involves signaling through the melanocortin type 1 receptor (MC-1R) that regulates the switch between pheomelanogenesis and eumelanogenesis. However, the involve

Externí odkaz: http://hdl.handle.net/10454/3009

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Akademický článek

Fas signaling is involved in the control of hair follicle response to chemotherapy.

Autor: Sharov, A.A., Siebenhaar, F., Sharova, T.Y., Botchkareva, Natalia V., Gilchrest, B.A., Botchkarev, Vladimir A.

Chemotherapeutic agents induce p53-dependent apoptosis in the hair follicle (HF) resulting in hair loss, a common side effect of cancer therapy. Here, we show that Fas as a p53 target plays important role in the HF response to cyclophosphamide. Speci

Externí odkaz: http://hdl.handle.net/10454/3967

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Akademický článek

Noggin overexpression inhibits eyelid opening by altering epidermal apoptosis and differentiation.

Autor: Sharov, A.A., Weiner, L., Sharova, T.Y., Siebenhaar, F., Atoyan, R., Reginato, A.M., McNamara, C.A., Funa, K., Gilchrest, B.A., Brissette, J.L., Botchkarev, Vladimir A.

Contact of developing sensory organs with the external environment is established via the formation of openings in the skin. During eye development, eyelids first grow, fuse and finally reopen, thus providing access for visual information to the reti

Externí odkaz: http://hdl.handle.net/10454/3595

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