Zobrazeno 1 - 10
of 194
pro vyhledávání: '"GIAN LUIGI RUSSO"'
Autor:
Carmela Spagnuolo, Francesco Mautone, Anna Maria Iole Meola, Stefania Moccia, Giuseppe Di Lorenzo, Carlo Buonerba, Gian Luigi Russo
Publikováno v:
Molecules, Vol 29, Iss 21, p 5176 (2024)
Bladder cancer, which has a rising incidence, is the 10th most common cancer. The transitional cell carcinoma histotype is aggressive and often current therapies are ineffective. We investigated the anti-proliferative effect of quercetin, a natural f
Externí odkaz:
https://doaj.org/article/8f18ac6e2ad94404968d427a34bf2e27
Autor:
Alessandra Gallo, Ylenia Maria Penna, Maria Russo, Marco Rosapane, Elisabetta Tosti, Gian Luigi Russo
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
The last decades have seen an increase in the isolation and characterization of anticancer compounds derived from marine organisms, especially invertebrates, and their use in clinical trials. In this regard, ascidians, which are included in the subph
Externí odkaz:
https://doaj.org/article/857426b598b84b1d89b5a3bb81536145
Autor:
Maria Russo, Annamaria Di Giacomo, Federica Fiore, Carmela Spagnuolo, Virginia Carbone, Paola Minasi, Gian Luigi Russo
Publikováno v:
Current Research in Biotechnology, Vol 8, Iss , Pp 100266- (2024)
The evidence linking high levels of environmental pollutants to chronic degenerative diseases is alarming, with heavy metals (HM) identified as a key factor. Research suggests that certain phytochemicals in the diet can reduce HM levels and mitigate
Externí odkaz:
https://doaj.org/article/5b9a6ee74ab44f2cbaf4205e288cda42
Autor:
Giuseppina Crescente, Giovanni Cascone, Antonio Petruzziello, Aziz Bouymajane, Maria Grazia Volpe, Gian Luigi Russo, Stefania Moccia
Publikováno v:
Foods, Vol 12, Iss 14, p 2678 (2023)
The wine industry produces large amounts of grape pomace (GP), a waste that needs to be disposed of properly. Bioactive compounds with high added value can be recovered from GP as an interesting strategy to reduce the environmental impact. Here, two
Externí odkaz:
https://doaj.org/article/a84c3d5e563549468a08c91380af686d
Autor:
Deborah Giordano, Angelo Facchiano, Stefania Moccia, Anna Maria Iole Meola, Gian Luigi Russo, Carmela Spagnuolo
Publikováno v:
Foods, Vol 12, Iss 10, p 1953 (2023)
The aryl hydrocarbon receptor (AhR) is a highly conserved environmental sensor, historically known for mediating the toxicity of xenobiotics. It is involved in numerous cellular processes such as differentiation, proliferation, immunity, inflammation
Externí odkaz:
https://doaj.org/article/1db62bf6a628434889f938463b806ddc
Autor:
Stefania Moccia, Maria Russo, Miriana Durante, Marcello S. Lenucci, Giovanni Mita, Gian Luigi Russo
Publikováno v:
Current Research in Biotechnology, Vol 2, Iss , Pp 74-82 (2020)
Chronic lymphocytic leukemia (CLL) is the most frequent form of leukemia in the adult population. From an asymptomatic state, which can lay for years, CLL rapidly evolves becoming fatal. Apoptosis resistance and induction of a protective form of auto
Externí odkaz:
https://doaj.org/article/cf22416de17a43a09ca345dd6aedf986
Autor:
Carmela Spagnuolo, Federica Moccia, Idolo Tedesco, Eva Adabbo, Lucia Panzella, Gian Luigi Russo, Alessandra Napolitano
Publikováno v:
Antioxidants, Vol 12, Iss 2, p 421 (2023)
The production of fruit distillates generates solid residues which are potentially rich in bioactive compounds worthy of valorization and exploitation. We report herein the in vitro antioxidant and antiproliferative properties of an extract obtained
Externí odkaz:
https://doaj.org/article/0c5b3585b2494b81830cd0b4ba558f2d
Publikováno v:
Chemical Engineering Transactions, Vol 87 (2021)
The present study aimed to evaluate the effects of active edible coating (AEC) on fresh fruits to extend the shelf life (15 days) and maintain their nutraceutical content by minimizing the rate of respiration and reducing the water loss. The coating
Externí odkaz:
https://doaj.org/article/a3de060c46e148718a649941000aa237
Autor:
Andy Wai Kan Yeung, Nikolay T. Tzvetkov, Vijai K. Gupta, Subash C. Gupta, Gorka Orive, Günther K. Bonn, Bernd Fiebich, Anupam Bishayee, Thomas Efferth, Jianbo Xiao, Ana Sanches Silva, Gian Luigi Russo, Maria Daglia, Maurizio Battino, Ilkay Erdogan Orhan, Ferdinando Nicoletti, Michael Heinrich, Bharat Bhushan Aggarwal, Marc Diederich, Maciej Banach, Wolfram Weckwerth, Rudolf Bauer, George Perry, Edward A. Bayer, Lukas A. Huber, Jean-Luc Wolfender, Robert Verpoorte, Francisco A. Macias, Michael Wink, Marc Stadler, Simon Gibbons, Alejandro Cifuentes, Elena Ibanez, Gérard Lizard, Rolf Müller, Michael Ristow, Atanas G. Atanasov
Publikováno v:
Current Research in Biotechnology, Vol 1, Iss , Pp 34-40 (2019)
Biotechnology is an evolving research field that covers a broad range of topics. Here we aimed to evaluate the latest research literature, to identify prominent research themes, major contributors in terms of institutions, countries/regions, and jour
Externí odkaz:
https://doaj.org/article/14283150f82241a1915d00a92924f11f
Publikováno v:
Molecules, Vol 26, Iss 19, p 5810 (2021)
Using a pharmacophore model based on the experimental structure of AKT-1, we recently identified the compound STL1 (ZINC2429155) as an allosteric inhibitor of AKT-1. STL1, was able to reduce Ser473 phosphorylation, thus inhibiting the PI3K/AKT pathwa
Externí odkaz:
https://doaj.org/article/487fd2cf407f4535ad73673bdc113838