Zobrazeno 1 - 10
of 1 085
pro vyhledávání: '"GHR"'
Autor:
Ghadeer Falah, Alina Kurolap, Tamar Paperna, Nina Ekhilevitch, Nivin Moustafa, Nadine Damouny-Naoum, Yam Amir, Lital Sharvit, Rihan Moghrabi, Gamal Hassoun, Fuad Fares, Hagit Baris Feldman, Gil Atzmon
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The Druze are a distinct group known for their close community, traditions, and consanguineous marriages, dating back to the eleventh century. This practice has led to unique genetic variations, impacting both pathology and gene-associated p
Externí odkaz:
https://doaj.org/article/249700d13bfb4f6c99f10cf27bb24013
Publikováno v:
Experimental Gerontology, Vol 196, Iss , Pp 112586- (2024)
The Growth Hormone Receptor (GHR) gene encodes a protein that is essential for mediating the biological effects of growth hormone (GH). A series of molecular events are set off when GH binds to its receptor, resulting in a variety of physiological re
Externí odkaz:
https://doaj.org/article/695f7640d5914f7d8dabcd1e8aa33e29
Autor:
Reetobrata Basu, Prateek Kulkarni, Deborah Swegan, Silvana Duran-Ortiz, Arshad Ahmad, Lydia J. Caggiano, Emily Davis, Christopher Walsh, Edward Brenya, Adeel Koshal, Rich Brody, Uday Sandbhor, Sebastian J. C. M. M. Neggers, John J. Kopchick
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7438 (2024)
Chemotherapy treatment against pancreatic ductal adenocarcinoma (PDAC) is thwarted by tumoral activation of multiple therapy resistance pathways. The growth hormone (GH)–GH receptor (GHR) pair is a covert driver of multimodal therapy resistance in
Externí odkaz:
https://doaj.org/article/1a3f8bb5ee834aec859077d1d8d528f8
Autor:
Patricia Mora‐Criollo, Reetobrata Basu, Yanrong Qian, Kevin Funk, Stephen Bell, Jonathan A. Young, Edward O. List, Jaime A. Costales, Jaime Guevara‐Aguirre, Mario J. Grijalva, John J. Kopchick
Publikováno v:
FEBS Open Bio, Vol 13, Iss 7, Pp 1346-1356 (2023)
Chagas disease (CD) is one of the most devasting parasitic diseases in the Americas, affecting 7–8 million people worldwide. In vitro and in vivo experiments have demonstrated that growth hormone (GH) serum levels decrease as CD progresses. Interes
Externí odkaz:
https://doaj.org/article/63343503754d4c3b9c22ff8271705ef3
Autor:
Fatemeh Bitarafan, Mehrnoosh Khodaeian, Fatemeh Garrousi, Raziyeh Khalesi, Donya Ghazi Nader, Behnam Karimi, Reza Alibakhshi, Masoud Garshasbi
Publikováno v:
BMC Endocrine Disorders, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background Human growth hormone (hGH) plays a crucial role in growth by binding to growth hormone receptor (GHR) in target cells. Binding of GH molecules to their cognate receptors triggers downstream signaling pathways leading to the transc
Externí odkaz:
https://doaj.org/article/db3b690ee9a24323b8855126b00ef7cb
Autor:
Bowen Hu, Changbin Zhao, Xiangchun Pan, Haohui Wei, Guodong Mo, Mingjian Xian, Wen Luo, Qinghua Nie, Hongmei Li, Xiquan Zhang
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-18 (2023)
Abstract Background Myoblast differentiation requires metabolic reprogramming driven by increased mitochondrial biogenesis and oxidative phosphorylation. The canonical GH-GHR-IGFs axis in liver exhibits a great complexity in response to somatic growt
Externí odkaz:
https://doaj.org/article/0cc8167200694870831e445a886c478c
Autor:
M.L. Aryayev, L.I. Senkivska
Publikováno v:
Український журнал Перинатологія і педіатрія, Iss 1(93), Pp 64-68 (2023)
Результативність новітніх генетичних технологій для досягнення прогресу в діагностиці дефіциту гормона роста (ДГР) та прогнозуванні р
Externí odkaz:
https://doaj.org/article/678a4f0fdaf944908b0ed5e59eb0c7a4
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Haque A, Sahu V, Lombardo JL, Xiao L, George B, Wolff RA, Morris JS, Rashid A, Kopchick JJ, Kaseb AO, Amin HM
Publikováno v:
Journal of Hepatocellular Carcinoma, Vol Volume 9, Pp 823-837 (2022)
Abedul Haque,1 Vishal Sahu,1 Jamie Lynne Lombardo,2 Lianchun Xiao,3 Bhawana George,1 Robert A Wolff,4 Jeffrey S Morris,3 Asif Rashid,2 John J Kopchick,5,6 Ahmed O Kaseb,4 Hesham M Amin1,7 1Department of Hematopathology, The University of Texas MD And
Externí odkaz:
https://doaj.org/article/65c06e7b09464c8eab63a5d3c81d552e