Zobrazeno 1 - 10
of 78
pro vyhledávání: '"GHASSAN ABU SHEIKHA"'
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 58 (2022)
Abstract A series of N-(benzoylphenyl)-carboxamide derivatives (2a, 2b, 3a, 3b, 4a, 4b, 5a, 5b, 6a and 6b) was prepared with good yields by reacting the corresponding carbonyl chlorides with aminobenzophenones at room temperature. This was followed b
Externí odkaz:
https://doaj.org/article/9c80f1487385400e9ca2bb564bead2f3
Autor:
Dima A. Sabbah, Shorooq Alqazaqi, Reema Abu Khalaf, Maram Aburezeq, Ghassan Abu Sheikha, Ghadeer Albadawi
Publikováno v:
Current Computer-Aided Drug Design. 18:9-25
Background: Diabetes mellitus is a chronic metabolic disorder, characterized by hyperglycemia over a prolonged period, disturbance of fat, protein and carbohydrate metabolism, resulting from defective insulin secretion, insulin action or both. Dipept
Autor:
Kamal Sweidan, Ghassan Abu Sheikha, Sawsan Shraim, Bara’a A. Al-Azaideh, Wamidh H. Talib, Rima Hajjo, Aya M. Al-Zuheiri, Dima A. Sabbah
Publikováno v:
Acta Pharmaceutica, Vol 71, Iss 4, Pp 545-565 (2021)
Phosphoinositide 3-kinase α (PI3Kα) is a propitious target for designing anticancer drugs. A series of new N’-(diphenylmethylene)benzenesulfonohydrazide was synthesized and characterized using FT-IR, NMR (1H and 13C), HRMS, and elemental analysis
Autor:
Sanaa K. Bardaweel, Raymond Thomas, Boulanouar Bakchiche, Eid Alsbou, Ghassan Abu Sheikha, Mohammad Al-Hwaiti, Thu Huong Pham
Publikováno v:
Food Science & Nutrition, Vol 9, Iss 1, Pp 282-289 (2021)
Background The chemical composition of Handal (Citrullus colocynthis L.) seed oil cultivated in Jordan deserts was characterized, and its bioactivity was evaluated. Methods The oil was extracted from the grinded seeds in 500 ml Soxhlet extractor for
Autor:
Suhair Hikmat, Ghassan Abu Sheikha, Yusuf Al-Hiari, Tariq Al-Qirim, Waseem El-Huneidi, Ghassan Shattat
Publikováno v:
Molecules, Vol 16, Iss 10, Pp 8292-8304 (2011)
In the search for new potential antihyperlipidemic agents, the present study focuses on the synthesis of novel N-(benzoylphenyl)-5-substituted-1H-indole-2-carboxamides (compounds 8-12, 15, 16, 18) and investigating their antihyperlipidemic activity u
Externí odkaz:
https://doaj.org/article/e3dbafc42a014a84b4e06fe56189c519
Autor:
Tariq Al-Qirim, Moyad Shahwan, Waseem El-Huneidi, Yusuf Al-Hiari, Ghassan Shattat, Ghassan Abu Sheikha, Rania Al-Qirim
Publikováno v:
Molecules, Vol 15, Iss 9, Pp 5840-5849 (2010)
The lipid-lowering activity of a series of novel N-(benzoylphenyl)-5-fluoro-1H-indole-2-carboxamide derivatives has been studied in Triton WR-1339-induced hyperlipidemia in rats. The test animals were divided into four groups: control, hyperlipidemic
Externí odkaz:
https://doaj.org/article/d60dc9c2db4e4b26ae5d07a1336ee658
Publikováno v:
Molecules, Vol 15, Iss 8, Pp 5721-5733 (2010)
Cholesteryl ester transfer protein (CETP) is a glycoprotein involved in transporting lipoprotein particles and neutral lipids between high-density lipoprotein (HDL) and low density lipoproteins (LDL) and therefore its a proper target for treating dys
Externí odkaz:
https://doaj.org/article/dcdeadbd76df409bb3754f3ec74e5a34
Autor:
DIMA A. SABBAH, BARA’A A. AL-AZAIDEH, WAMIDH H. TALIB, RIMA HAJJO, KAMAL SWEIDAN, AYA M. AL-ZUHEIRI, GHASSAN ABU SHEIKHA, SAWSAN SHRAIM
Publikováno v:
Acta Pharmaceutica
Volume 71
Issue 4
Volume 71
Issue 4
Phosphoinositide 3-kinase α (PI3Kα) is a propitious target for designing anticancer drugs. A series of new N'-(diphenylmethylene)benzenesulfonohydrazide was synthesized and characterized using FT-IR, NMR (1H and 13C), HRMS, and elemental analysis.
Autor:
Mohammad S, Al-Hwaiti, Eid M, Alsbou, Ghassan, Abu Sheikha, Boulanouar, Bakchiche, Thu Huong, Pham, Raymond H, Thomas, Sanaa K, Bardaweel
Publikováno v:
Food Science & Nutrition
Background The chemical composition of Handal (Citrullus colocynthis L.) seed oil cultivated in Jordan deserts was characterized, and its bioactivity was evaluated. Methods The oil was extracted from the grinded seeds in 500 ml Soxhlet extractor for
Autor:
Ghassan Abu Sheikha, Mustafa S Aboumair, Samah A. Ata, Dima A. Sabbah, Majdi M. Bkhaitan, Tariq Al-Qirim, Kamal Sweidan, Ghassan Shattat, Samah A Ala, Haneen M Abuzaid, Suhair H Jasim
Publikováno v:
Chemical and Pharmaceutical Bulletin. 66:953-958
A new series of imidazole-5-carboxamide derivatives were prepared and tested for their anti-hyperlipidemic activity in Triton-WR-1339-induced hyperlipidemic Wistar rats. The purpose of this research was to improve benzophenone carboxamides water solu