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pro vyhledávání: '"GFP, green fluorescence protein"'
Akademický článek
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Autor:
Chuyao Liao, Di Wang, Ying Zhang, Zunjian Zhang, Fengguo Xu, Siyuan Qin, Yuxin Zhang, Danting Li, Yuan Tian, Jie Chen
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 763-780 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Intestinal toxicity induced by chemotherapeutics has become an important reason for the interruption of therapy and withdrawal of approved agents. In this study, we demonstrated that chemotherapeutics-induced intestinal damage were commonly character
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7af930bc5ea3c9fbae9d582539b35a5f
https://doi.org/10.1016/j.apsb.2020.07.017
https://doi.org/10.1016/j.apsb.2020.07.017
Publikováno v:
Advanced Drug Delivery Reviews
Graphical abstract
Gene therapy has been widely investigated for the treatment of genetic, acquired, and infectious diseases. Pioneering work utilized viral vectors; however, these are suspected of causing serious adverse events, resulting in th
Gene therapy has been widely investigated for the treatment of genetic, acquired, and infectious diseases. Pioneering work utilized viral vectors; however, these are suspected of causing serious adverse events, resulting in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff7413733ccbe4eda7411005d2c1ea69
http://europepmc.org/articles/PMC8518240
http://europepmc.org/articles/PMC8518240
Autor:
Klaus H. Kaestner, Kirk J. Wangensteen, Yue J. Wang, Adam M. Zahm, Amber W. Wang, Ashleigh Morgan
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims The adult liver is the main detoxification organ and routinely is exposed to environmental insults but retains the ability to restore its mass and function upon tissue damage. However, extensive injury can lead to liver failure, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9f21a5127e26d4243ba88fa52d55199
https://doi.org/10.1101/664862
https://doi.org/10.1101/664862
Autor:
Yasuaki Shirayoshi, Kohei Fukuoka, Kumi Morikawa, Yoshiko Suyama, Shunjiro Yagi, Kazuomi Nakamura, Kenshiro Yamamoto, Tetsuya Ohbayashi, Ichiro Hisatome
Publikováno v:
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 18, Iss, Pp-(2019)
Biochemistry and Biophysics Reports, Vol 18, Iss, Pp-(2019)
In the present study, we have established a novel transgenic mouse and transgenic rats with dual reporters of EGFP and ELuc. In these transgenic (Tg) rodents, both GFP fluorescent and luciferase luminescent signals were ubiquitously detected in the h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d3ff2dc0bfce64d3be01b86a85a9ef8
https://pubmed.ncbi.nlm.nih.gov/31193220
https://pubmed.ncbi.nlm.nih.gov/31193220
Autor:
Akihiro Umezawa, Yoshitaka Iso, Sayaka Usui, Masashi Toyoda, Hiroshi Suzuki, Jeffrey L. Spees
Publikováno v:
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 16, Iss, Pp 79-87 (2018)
Biochemistry and Biophysics Reports, Vol 16, Iss, Pp 79-87 (2018)
We investigated whether mesenchymal stem cell (MSC)-based treatment could inhibit neointimal hyperplasia in a rat model of carotid arterial injury and explored potential mechanisms underlying the positive effects of MSC therapy on vascular remodeling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb82cb41a760daa4121053beeae293f
https://pubmed.ncbi.nlm.nih.gov/30377672
https://pubmed.ncbi.nlm.nih.gov/30377672
Publikováno v:
International Journal of Gynecological Cancer
Tumorigenesis is a complex multistep and multifactorial biological process involving the activation of multiple oncogenes and inactivation of tumor suppressor genes; however, studies on the effects and mechanisms of these genes in ovarian cancer are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed92b37f6f7e9bdb10f68062b76eb86
http://europepmc.org/articles/PMC4047297
http://europepmc.org/articles/PMC4047297
Autor:
Laurence Coutellier, Chloe E. Page
Publikováno v:
EBioMedicine
An imbalance between neuronal excitation and inhibition represents a core feature in multiple neuropsychiatry disorders, necessitating the development of novel strategies to calibrate the excitatory–inhibitory balance of therapeutics. Here we ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30783fd33ba25b45c6dcfb9509bac92a
http://europepmc.org/articles/PMC6161475
http://europepmc.org/articles/PMC6161475
Autor:
Karl Kossen, Toshiyuki Koya, Erwin W. Gelfand, Barry Polisky, Joseph J. Lucas, Shawn Zinnen, Tricia N. Lively, Ivan Richards, Annette Balhorn, Katsuyuki Takeda
Publikováno v:
The Journal of Allergy and Clinical Immunology
Background RNA interference is an endogenous cellular mechanism in which short interfering RNAs (siRNAs) direct the sequence specific degradation of a target mRNA. siRNAs can be synthesized with chemical modifications to increase stability and reduce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::977240a92dac71c8041fe1b55f14258f
https://doi.org/10.1016/j.jaci.2007.08.029
https://doi.org/10.1016/j.jaci.2007.08.029
Autor:
Yun Liao, Yi Sheng, Shaozhong Dong, Qihan Li, Chenghong Dong, Shaohui Ma, Longding Liu, Yanchun Che, Hongling Zhao, Lichun Wang, Li Jiang
Publikováno v:
Journal of Clinical Virology
The pathological mechanism of SARS-CoV infection was investigated. The gene for the SARS-CoV non-structural protein 10, which is located in the open reading frame of pp1a/pp1ab gene, was synthesized and used to screen for the specific cellular gene c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b1f72204b3dd0ec29a3091704d3b781
https://doi.org/10.1016/j.jcv.2004.12.019
https://doi.org/10.1016/j.jcv.2004.12.019