Výsledky vyhledávání - "GFP, Green fluorescent protein"

Delta-like 1–Expressing Cells at the Gland Base Promote Proliferation of Gastric Antral Stem Cells in Mouse

Autor: Elise S. Hibdon, Elizabeth Delgado, Nobukatsu Horita, Theresa M. Keeley, Daniel Lafkas, Linda C. Samuelson, Christian W. Siebel

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 1, Pp 275-287 (2022)

Background & Aims Notch pathway signaling maintains gastric epithelial cell homeostasis by regulating stem cell proliferation and differentiation. We previously identified NOTCH1 and NOTCH2 as the key Notch receptors controlling gastric stem cell fun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccacea6aeb7ccb4eac58ae85430d9382
https://doi.org/10.1016/j.jcmgh.2021.08.012

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HOP protein expression in the hippocampal dentate gyrus is acutely downregulated in a status epilepticus mouse model

Autor: Tomokatsu Hori, YA Alshebib, Taichi Kashiwagi

Publikováno v: IBRO Neuroscience Reports, Vol 11, Iss, Pp 183-193 (2021)
IBRO Neuroscience Reports

Status epilepticus (SE) is a neurological emergency, and delayed management can lead to higher morbidity and mortality. It is thought that prolonged seizures stimulate stem cells in the hippocampus and that epileptogenesis may arise from aberrant con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d32bbffc59bb8d8e87e50315da1131
http://www.sciencedirect.com/science/article/pii/S2667242121000440

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Salmonella flagella confer anti-tumor immunological effect via activating Flagellin/TLR5 signalling within tumor microenvironment

Autor: Bo Tang, Cunjie Chang, Guo Chen, Xiufeng Liu, Zi-Chun Hua, Xiawei Cheng, Jianxiang Chen, Heng Dong, Yiting Qiao

Publikováno v: Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 3165-3177 (2021)
Acta Pharmaceutica Sinica. B

Salmonella mediated cancer therapy has achieved remarkable anti-tumor effects in experimental animal models, but the detailed mechanism remains unsolved. In this report, the active involvement of the host immune response in this process was confirmed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa58001e49d3f5032ed52d1763576536
https://doi.org/10.1016/j.apsb.2021.04.019

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Evidence of a Myenteric Plexus Barrier and Its Macrophage-Dependent Degradation During Murine Colitis: Implications in Enteric Neuroinflammation

Autor: Tamas Kovacs, Nandor Nagy, Ryo Hotta, Ildikó Bódi, Zoltán Varga, Allan M. Goldstein, Viktória E. Tóth, Rhian Stavely, David Dora, Szilamér Ferenczi, Krisztina J. Kovács

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1617-1641 (2021)

Background & Aims Neuroinflammation in the gut is associated with many gastrointestinal (GI) diseases, including inflammatory bowel disease. In the brain, neuroinflammatory conditions are associated with blood-brain barrier (BBB) disruption and subse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2a0ac8fd2f5ff2f3874cc3cf2cf105d
http://europepmc.org/articles/PMC8551790

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PIR-B Regulates CD4+ IL17a+ T-Cell Survival and Restricts T-Cell–Dependent Intestinal Inflammatory Responses

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1479-1502 (2021)

Background & Aims CD4+ T cells are regulated by activating and inhibitory cues, and dysregulation of these proper regulatory inputs predisposes these cells to aberrant inflammation and exacerbation of disease. We investigated the role of the inhibito

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5bc9234d68120dd2171e099da6a99f4
http://europepmc.org/articles/PMC8531983

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Amino acid residue at the 165th position tunes EYFP chromophore maturation. A structure-based design

Autor: Vladimir Z. Pletnev, Eugene G. Maksimov, Anastasia V. Mamontova, Elena A. Protasova, Rustam H. Ziganshin, Konstantin A. Lukyanov, Nadya V. Pletneva, Sergei Pletnev, Tatiana R. Simonyan, Liya Muslinkina, Alexey M. Bogdanov

Publikováno v: Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 2950-2959 (2021)

Graphical abstract
For the whole GFP family, a few cases, when a single mutation in the chromophore environment strongly inhibits maturation, were described. Here we study EYFP-F165G – a variant of the enhanced yellow fluorescent protein – o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e86d1191f9c8ae5e9ff3d8772e885cc6
http://europepmc.org/articles/PMC8163865

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Role of AMPK and Akt in triple negative breast cancer lung colonization

Autor: Heidi L. Weiss, B. Mark Evers, Jeremy Johnson, Zeta Chow, Piotr G. Rychahou, Eun Y. Lee

Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 4, Pp 429-438 (2021)
Neoplasia (New York, N.Y.)

Triple negative breast cancer (TNBC) is an aggressive disease with a 5-y relative survival rate of 11% after distant metastasis. To survive the metastatic cascade, tumor cells remodel their signaling pathways by regulating energy production and upreg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f579366bddfd960dbbe114706d860b9
http://www.sciencedirect.com/science/article/pii/S1476558621000154

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