Zobrazeno 1 - 10
of 10
pro vyhledávání: '"GFL mimetic"'
Autor:
Yulia A. Sidorova, Maxim M. Bespalov, Agnes W. Wong, Oleg Kambur, Viljami Jokinen, Tuomas O. Lilius, Ilida Suleymanova, Gunnar Karelson, Pekka V. Rauhala, Mati Karelson, Peregrine B. Osborne, Janet R. Keast, Eija A. Kalso, Mart Saarma
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Neuropathic pain caused by nerve damage is a common and severe class of chronic pain. Disease-modifying clinical therapies are needed as current treatments typically provide only symptomatic relief; show varying clinical efficacy; and most have signi
Externí odkaz:
https://doaj.org/article/386952903bfa44e9aacfe166bb459eff
Autor:
Sidorova, Yulia A., Saarma, Mart
Glial cell line-derived neurotrophic factor (GDNF) family ligands (GFLs) are able to promote the survival of multiple neuronal populations in the body and, therefore, hold considerable promise for disease-modifying treatments of diseases and conditio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1593::0840b691e54547039add8de277ea0d98
http://hdl.handle.net/10138/321872
http://hdl.handle.net/10138/321872
Autor:
Mart Saarma, Yulia Sidorova
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 6575, p 6575 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 6575, p 6575 (2020)
Glial cell line-derived neurotrophic factor (GDNF) family ligands (GFLs) are able to promote the survival of multiple neuronal populations in the body and, therefore, hold considerable promise for disease-modifying treatments of diseases and conditio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeed8c0a976b57495e51db8a6c1d8c1d
https://pubmed.ncbi.nlm.nih.gov/32911810
https://pubmed.ncbi.nlm.nih.gov/32911810
Autor:
Viisanen, Hanna1,2, Nuotio, Ulpukka3, Kambur, Oleg1, Mahato, Arun Kumar3, Jokinen, Viljami1, Lilius, Tuomas1,2, Li, Wei3,4, Santos, Hélder A4,5, Karelson, Mati6, Rauhala, Pekka1,2, Kalso, Eija1,7, Sidorova, Yulia A3,7 yulia.sidorova@helsinki.fi
Publikováno v:
Molecular Pain. 8/18/2020, Vol. 16, p1-19. 19p.
Akademický článek
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Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Neurodegenerative Diseases; Mar2017 Supplement, Vol. 17, p1-1890, 1890p
Publikováno v:
Neurodegenerative Diseases; 2016 Supplement, Vol. 17, p591-1890, 1300p, 1 Color Photograph, 26 Diagrams, 15 Charts, 16 Graphs
A limited number of drug targets can be exploited by conventional drug-like compounds as the vast majority of disease-associated targets are involved in protein-protein interactions (PPI). PPI targets possess binding surfaces that lack a well-defined
Externí odkaz:
https://hdl.handle.net/2144/42740
Autor:
Arun Kumar Mahato, Hélder A. Santos, Eija Kalso, Hanna Viisanen, Mati Karelson, Viljami Jokinen, Oleg Kambur, Yulia Sidorova, Ulpukka Nuotio, Tuomas Lilius, Pekka Rauhala, Wei Li
Publikováno v:
Molecular Pain
The glial cell line-derived neurotrophic factor (GDNF) family ligands (GFLs) alleviate symptoms of experimental neuropathy, protect and stimulate regeneration of sensory neurons in animal models of neuropathic pain, and restore their functional activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed45f369e4b59d044795f72533ab69d
http://europepmc.org/articles/PMC7440726
http://europepmc.org/articles/PMC7440726