Zobrazeno 1 - 10
of 17
pro vyhledávání: '"GFAP, glial fibrillary acid protein"'
'Effect of valerenic acid on neuroinflammation in a MPTP-induced mouse model of Parkinson’s disease'
Autor:
Alfredo Rodríguez-Cruz, Guadalupe García-Alcocer, Antonio Romo-Mancillas, Jesus Mendiola-Precoma, Laura C. Berumen, Jesica Escobar-Cabrera
Publikováno v:
IBRO Reports, Vol 8, Iss, Pp 28-35 (2020)
IBRO Reports
IBRO Reports
Highlights • Valerenic acid modulates the neuropathological markers of Parkinson´s disease. • Valerenic acid attenuates neuroinflammation in a Parkinson´s disease model. • Astrocytes and cytokines are targets in the anti-inflammatory effect o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b09491839f0fbe941359d445d0490d1
http://www.sciencedirect.com/science/article/pii/S2451830119319405
http://www.sciencedirect.com/science/article/pii/S2451830119319405
Autor:
Gert Tollesson, Jolyn Khoo
Publikováno v:
International Journal of Surgery Case Reports
Highlights • Central Neurocytomas are a rare intracranial tumour, often presenting with obstructive hydrocephalus. • Isolated lesions in the posterior third ventricle are an uncommon location for Central Neurocytomas. • An endoscopic approach t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19f9d40981b410b9f486d8fab0f7d58d
https://doi.org/10.1016/j.ijscr.2020.02.042
https://doi.org/10.1016/j.ijscr.2020.02.042
Autor:
Nan Du, Bingqiang He, Hui Li, Ting Yang, Chunshuai Sun, Honghua Song, Yongjun Wang, Yingjie Wang
Publikováno v:
The Journal of Biological Chemistry
Adult mammalian astrocytes are sensitive to inflammatory stimuli in the context of neuropathology or mechanical injury, thereby affecting functional outcomes of the central nervous system (CNS). In contrast, glial cells residing in the spinal cord of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbbceb6a544772110ebb1526ac88afb3
http://europepmc.org/articles/PMC8065226
http://europepmc.org/articles/PMC8065226
Autor:
Burkhard Greve, Nikos K. Karamanos, Martin Götte, Achilleas D. Theocharis, Aristidis Moustakas, Dimitra Manou, Dimitris Kletsas, Panagiotis Bouris
Publikováno v:
Matrix Biology Plus, Vol 6, Iss, Pp 100033-(2020)
Matrix Biology Plus
Matrix Biology Plus
Despite the functional role of serglycin as an intracellular proteoglycan, a variety of malignant cells depends on its expression and constitutive secretion to advance their aggressive behavior. Serglycin arose to be a biomarker for glioblastoma, whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::964f00930fce6b4c76cd7c507824d68d
http://www.sciencedirect.com/science/article/pii/S2590028520300144
http://www.sciencedirect.com/science/article/pii/S2590028520300144
Autor:
Ye, Zhao, Shikara, Keshiya, Farzaneh, Atashrazm, Jianqun, Gao, Lars M, Ittner, Dario R, Alessi, Glenda M, Halliday, Yuhong, Fu, Nicolas, Dzamko
Publikováno v:
Neurobiology of Disease, Vol 120, Iss, Pp 76-87 (2018)
Neurobiology of Disease
Neurobiology of Disease
Leucine-rich repeat kinase 2 (LRRK2) is genetically implicated in both familial and sporadic Parkinson's disease (PD). Moreover, LRRK2 has emerged as a compelling therapeutic target for the treatment of PD. Consequently, there is much interest in und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::37c7da1f00a1694db424741d7b8f0dfd
http://www.sciencedirect.com/science/article/pii/S0969996118302225
http://www.sciencedirect.com/science/article/pii/S0969996118302225
Autor:
Carlos Gilberto Carlotti, Ingmar Blümcke, João Alberto Assirati, Roland Coras, Katja Kobow, Gustavo Henrique de Souza e Rezende, Jose Eduardo Peixoto-Santos, Carlos Ernesto Garrido Salmon, Antônio Carlos dos Santos, Tonicarlo Rodrigues Velasco, João Pereira Leite
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
NeuroImage : Clinical
NeuroImage: Clinical, Vol 28, Iss, Pp 102463-(2020)
Universidade de São Paulo (USP)
instacron:USP
NeuroImage : Clinical
NeuroImage: Clinical, Vol 28, Iss, Pp 102463-(2020)
Highlights • Hippocampal MTR in TLE does not add to volume or T2 signal regarding lateralization. • Extracellular CSPG are the most relevant correlate to MTR in hippocampal sclerosis. • Increased CSPG counterbalances neuron loss over the reduct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df5d3e074a22da52e3367948ce5e7a61
https://doi.org/10.1016/j.nicl.2020.102463
https://doi.org/10.1016/j.nicl.2020.102463
Autor:
Sarah Mustafa, Heather Martin, Ross B. Mounsey, Michael C. Nelson, Ronald M. Evans, Kinnari Sathe, Peter Teismann
Publikováno v:
Neuroscience
Highlights • We investigate the role of PPARδ in a model of Parkinson’s disease. • PPARδ is upregulated after the neurotoxin MPTP. • PPARδ antagonism enhances MPP+ toxicity which is reversible by PPARδ agonism. • PPARδ agonism protects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ddcb5e841eab2aa04672192ba2bb0d2
https://doi.org/10.1016/j.neuroscience.2013.02.058
https://doi.org/10.1016/j.neuroscience.2013.02.058
Autor:
Dirk A. Ridder, Markus Schwaninger
Publikováno v:
Experimental Neurology
Peroxisome proliferator-activated receptor γ (PPARγ) agonists have been shown to provide neuroprotection in a number of neurodegenerative diseases including Parkinson's disease and Alzheimer's disease. These protective effects are primarily conside
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14ba241f6ab90a2c6c0c969a38e70efe
https://doi.org/10.1016/j.expneurol.2012.08.012
https://doi.org/10.1016/j.expneurol.2012.08.012
Publikováno v:
ASN NEURO
ASN Neuro, Vol 5 (2013)
Scopus-Elsevier
ASN Neuro, Vol 5 (2013)
Scopus-Elsevier
The Notch pathway is a highly conserved signaling system essential for modulating neurogenesis and promoting astrogenesis. Similarly, the cAMP signaling cascade can promote astrocytic commitment in several cell culture models, such as the C6 glioma c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c62f9974c36273e69d2d47c71c1e710
https://pubmed.ncbi.nlm.nih.gov/24286475
https://pubmed.ncbi.nlm.nih.gov/24286475
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