Zobrazeno 1 - 10
of 39
pro vyhledávání: '"GEORGIOS N. TSAOUSIS"'
Autor:
Nikolaos Tsoulos, Eirini Papadopoulou, Konstantinos Agiannitopoulos, Dimitrios Grigoriadis, Georgios N. Tsaousis, Dimitra Bouzarelou, Helen Gogas, Theodore Troupis, Vassileios Venizelos, Elena Fountzilas, Maria Theochari, Dimitrios C. Ziogas, Stylianos Giassas, Anna Koumarianou, Athina Christopoulou, George Busby, George Nasioulas, Christos Markopoulos
Publikováno v:
Diagnostics, Vol 14, Iss 16, p 1826 (2024)
Breast cancer (BC) is the most prominent tumor type among women, accounting for 32% of newly diagnosed cancer cases. BC risk factors include inherited germline pathogenic gene variants and family history of disease. However, the etiology of the disea
Externí odkaz:
https://doaj.org/article/612be478b7e4406f9ed5f56e30ee7f3d
Autor:
Konstantinos Agiannitopoulos, Pinelopi Samara, Miranta Papadopoulou, Astradeni Efthymiadou, Eirini Papadopoulou, Georgios N. Tsaousis, George Mertzanos, Dimitrios Babalis, Klea Lamnissou
Publikováno v:
Hellenic Journal of Cardiology, Vol 62, Iss 4, Pp 278-284 (2021)
Objective: Several microRNA (miRNA) polymorphisms have been associated with susceptibility to specific health disorders, including cardiovascular diseases. The aim of the present study was to investigate whether four well-studied miRNA polymorphisms
Externí odkaz:
https://doaj.org/article/32a9235e2789465f9ea0e5630ba2752f
Autor:
Konstantinos Agiannitopoulos, Eirini Papadopoulou, Georgios N. Tsaousis, Georgia Pepe, Stavroula Kampouri, Mehmet Ali Kocdor, George Nasioulas
Publikováno v:
BMC Medical Genetics, Vol 20, Iss 1, Pp 1-4 (2019)
Abstract Background CHEK2 is involved in the DNA damage repair response Fanconi anemia (FA)-BRCA pathway. An increased risk for breast and other cancers has been documented in individuals who carry a single pathogenic CHEK2 variant. As for other gene
Externí odkaz:
https://doaj.org/article/9cd9b6a0109248969a8e2a424e37fa8e
Autor:
Georgios N. Tsaousis, Eirini Papadopoulou, Angela Apessos, Konstantinos Agiannitopoulos, Georgia Pepe, Stavroula Kampouri, Nikolaos Diamantopoulos, Theofanis Floros, Rodoniki Iosifidou, Ourania Katopodi, Anna Koumarianou, Christos Markopoulos, Konstantinos Papazisis, Vasileios Venizelos, Ioannis Xanthakis, Grigorios Xepapadakis, Eugeniu Banu, Dan Tudor Eniu, Serban Negru, Dana Lucia Stanculeanu, Andrei Ungureanu, Vahit Ozmen, Sualp Tansan, Mehmet Tekinel, Suayib Yalcin, George Nasioulas
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-19 (2019)
Abstract Background Hereditary cancer predisposition syndromes are responsible for approximately 5–10% of all diagnosed cancer cases. In the past, single-gene analysis of specific high risk genes was used for the determination of the genetic cause
Externí odkaz:
https://doaj.org/article/dc43f140d22c4f09805d95f871555460
Autor:
Konstantinos Agiannitopoulos, Eirini Papadopoulou, Georgios N. Tsaousis, Georgia Pepe, Stavroula Kampouri, Eleni Patsea, George Lypas, George Nasioulas
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 8, Iss 10, Pp n/a-n/a (2020)
Abstract Background Carriers with pathogenic variants in MSH2 have increased risk to develop colorectal, endometrium, ovarian, and other types of cancer. The PALB2 is associated with breast, ovarian, pancreatic, and prostate cancer. We describe the c
Externí odkaz:
https://doaj.org/article/2f71d7a46691488889c81edc5d993354
Autor:
Nikolaos Tsoulos, Konstantinos Agiannitopoulos, Georgia Pepe, Eirini Papadopoulou, Georgios N Tsaousis, Despina Apostolopoulou, Angeliki Meintani, Vassileios Venizelos, Christos Markopoulos, Rodoniki Iosifidou, Sofia Karageorgopoulou, Christos Christodoulou, Ioannis Natsiopoulos, Konstantinos Papazisis, Maria Vasilaki-Antonatou, Eleftherios Kabletsas, Amanta Psyrri, Stylianos Giassas, Dimitrios Ziogas, Efthalia Lalla, Anna Koumarianou, Christos Papadimitriou, Vahit Ozmen, Sualp Tansan, Kerim Kaban, Tahsin Ozatlı, Dan Tudor Eniu, Angelica Chiorean, Alexandru Blidaru, George Nasioulas
Publikováno v:
Cancer Research. 82:P2-09
Background: Breast cancer is the most frequently diagnosed cancer in women and about 10% of breast cancer cases are hereditary. BRCA1 and BRCA2 are the genes most frequently associated with Hereditary Breast Cancer, although there are numerous other
Autor:
ANGELA APESSOS, KONSTANTINOS AGIANNITOPOULOS, GEORGIA PEPE, GEORGIOS N. TSAOUSIS, PANAGIOTA PITTA, CHRYSANTHI BILI, LINA FLORENTIN, EMMANOUEL SALOUSTROS, ELEFTHERIOS KAMPLETSAS, DIMITRIOS TRYFONOPOULOS, NIKOLAOS TSOUKALAS, EVANGELOS BOURNAKIS, FLORA ZAGOURI, ATHANASSIOS KOTSAKIS, ANNA KOUMARIANOU, IPPOKRATIS KORANTZIS, IOANNIS BOUKOVINAS, GEORGE LYPAS, GEORGIOS FOUNTZILAS, VASILIKI MICHALAKI, SPYRIDON XYNOGALOS, HELENA LINARDOU, EIRINI PAPADOPOULOU, GEORGE NASIOULAS, VASSILIS GEORGOULIAS
Publikováno v:
Anticancer research. 42(12)
Male breast cancer (MBC) is a very rare disorder affecting approximately 1 in 833 men. Genetic predisposition is one of the most important risk factors of MBC with BRCA2 being the most commonly mutated gene in males diagnosed with breast cancer. Howe
Autor:
Konstantinos Agiannitopoulos, Kevisa Potska, Anna Douka, Iphigenia Gintoni, Georgios N. Tsaousis, Eirini Papadopoulou, George Nasioulas, Christos Yapijakis
Publikováno v:
Archives of Oral Biology. 150:105689
Autor:
Nikolaos Tsoulos, Sualp Tansan, Georgios N. Tsaousis, Aikaterini Tsantikidi, Dimitrios Fotiou, Bülent Orhan, Achilleas Adamidis, Eleni Galani, George Lypas, Vasiliki-Metaxa Mariatou, Evgenia Bourkoula, George Nasioulas, Ioannis Boukovinas, Okan Çakır, Dimitrios T. Trafalis, Evgenia Kapeni, Paraskevas Kosmidis, Mustafa Ozdogan, Eirini Papadopoulou, Onder Kirca, Tahsin Özatlı, Athanasios Fassas, Georgios Kapetsis, Nikolaos Touroutoglou
Publikováno v:
BMC Medical Genomics, Vol 14, Iss 1, Pp 1-21 (2021)
BMC Medical Genomics
BMC Medical Genomics
Background Tumor molecular profile analysis by Next Generation Sequencing technology is currently widely applied in clinical practice and has enabled the detection of predictive biomarkers of response to targeted treatment. In parallel with targeted
Autor:
Kerim Kaban, Sonia Maravelaki, Vahit Ozmen, Konstantinos Papazisis, Konstantinos Agiannitopoulos, Maria Vasilaki-Antonatou, Christos Markopoulos, Sofia Karageorgopoulou, Stavroula Kampouri, Vassileios Venizelos, Christos Christodoulou, Rodoniki Iosifidou, Georgios N. Tsaousis, Ioannis Natsiopoulos, Georgia Pepe, Athanassios Fassas, Eirini Papadopoulou, Dan Tudor Eniu, Sualp Tansan, George Nasioulas, Angelica Chiorean
Publikováno v:
Cancer Genomics Proteomics
Background Classification of splicing variants (SVs) in genes associated with hereditary cancer is often challenging. The aim of this study was to investigate the occurrence of SVs in hereditary cancer genes and the clinical utility of RNA analysis.