Zobrazeno 1 - 10 of 217 pro vyhledávání: '"GEOFFREY T. TUCKER"'
2
When Regional Anesthesia Met Pharmacokinetics
Autor: Laurence E. Mather, Geoffrey T. Tucker
Publikováno v: Anesthesiology. 136(4)
Pharmacokinetics of Local Anaesthetic Agents. By Tucker GT, Mather LE. Br J Anaesth 1975; 47(suppl 1):213–24 Information derived from measurements of blood concentrations of local anaesthetics can be extended by the application of pharmacokinetic a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e0e127c1ff1347cdbf5610baffe101a
https://pubmed.ncbi.nlm.nih.gov/35171978
Zobrazit plný text záznamu
3
A series acceleration algorithm for the gamma-Pareto (type I) convolution and related functions of interest for pharmacokinetics
Autor: Carl A. Wesolowski, Jane Alcorn, Geoffrey T. Tucker
Publikováno v: Journal of pharmacokinetics and pharmacodynamics. 49(2)
The gamma-Pareto type I convolution (GPC type I) distribution, which has a power function tail, was recently shown to describe the disposition kinetics of metformin in dogs precisely and better than sums of exponentials. However, this had very long r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc106f8c004186f0ce8603f81407d4e
https://pubmed.ncbi.nlm.nih.gov/34689268
Zobrazit plný text záznamu
4
Development and applications of a physiologically-based model of paediatric oral drug absorption
Autor: Trevor N. Johnson, Masoud Jamei, David B. Turner, J.J. Bonner, Geoffrey T. Tucker
Publikováno v: European Journal of Pharmaceutical Sciences. 115:57-67
There is increasing interest in paediatric drug absorption and the development of biopharmaceutics tools to facilitate the development of oral formulations for neonates, infants and children. We describe the development and application of a physiolog
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c4c04784527a73ad5d920987ecad94
https://doi.org/10.1016/j.ejps.2018.01.009
Zobrazit plný text záznamu
5
Prediction of olanzapine exposure in individual patients using physiologically based pharmacokinetic modelling and simulation
Autor: Titus Mohan, Michael D. Wiese, Porntipa Korprasertthaworn, Geoffrey T. Tucker, Andrew Rowland, Thomas M. Polasek, Michael J. Sorich, Amin Rostami-Hodjegan, Vidya Perera
Publikováno v: British Journal of Clinical Pharmacology
Aim: The aim of the present study was to predict olanzapine (OLZ) exposure in individual patients using physiologically based pharmacokinetic modelling and simulation (PBPK M & S). Methods: A 'bottom-up' PBPK model for OLZ was constructed in Simcyp®
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d900b2c796dd2b1c641ac76fe5a24f39
https://doi.org/10.1111/bcp.13480
Zobrazit plný text záznamu
6
Inhibition of human UDP-glucuronosyltransferase enzymes by lapatinib, pazopanib, regorafenib and sorafenib: Implications for hyperbilirubinemia
Autor: Nuy Chau, Kushari Burns, John O. Miners, Ross A. McKinnon, Kathleen M. Knights, Andrew Rowland, Geoffrey T. Tucker, Peter I. Mackenzie, Ganessan Kichenadasse
Publikováno v: Biochemical Pharmacology. 129:85-95
Kinase inhibitors (KIs) are a rapidly expanding class of drugs used primarily for the treatment of cancer. Data relating to the inhibition of UDP-glucuronosyltransferase (UGT) enzymes by KIs is sparse. However, lapatinib (LAP), pazopanib (PAZ), regor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05e959039998f63e56349d6ee9b92dc7
https://doi.org/10.1016/j.bcp.2017.01.002
Zobrazit plný text záznamu
7
The absorption kinetics of ketoconazole plays a major role in explaining the reported variability in the level of interaction with midazolam: Interplay between formulation and inhibition of gut wall and liver metabolism
Autor: Karen Rowland Yeo, Bo Liu, Mahmut Özdemir, Geoffrey T. Tucker, H. Kim Crewe, Amin Rostami-Hodjegan
Publikováno v: Biopharmaceutics & Drug Disposition. 38:260-270
The impact of different single oral doses of ketoconazole (KTZ) (100, 200 and 400 mg) and of staggering its dosage (400 mg at -12, -2, 0, 2 and 4 h), with respect to the administration of a single 5 mg oral dose of midazolam (MDZ) on the extent of in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e9c600e51c70cc9083d6889a5c652693
https://doi.org/10.1002/bdd.2058
Zobrazit plný text záznamu
9
Personalized Drug Dosage – Closing the Loop
Autor: Geoffrey T. Tucker
Publikováno v: Pharmaceutical Research
A brief account is given of various approaches to the individualization of drug dosage, including the use of pharmacodynamic markers, therapeutic monitoring of plasma drug concentrations, genotyping, computer-guided dosage using 'dashboards', and aut
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab42109c13a5662f26febce38d3bdbf4
http://europepmc.org/articles/PMC5498646
Zobrazit plný text záznamu
10
Current Challenges and Potential Opportunities for the Pharmaceutical Sciences to Make Global Impact: An FIP Perspective
Autor: Daniel Tang, Hanns-Christian Mahler, Michiho Ito, Hitoshi Sasaki, Michael B. Ward, Binodh DeSilva, Don Mager, Anke H. Maitland-van der Zee, Takuya Kumamoto, Geoffrey T. Tucker, Jennifer B. Dressman, Vinod P. Shah, Giovanni M. Pauletti
Publikováno v: Journal of pharmaceutical sciences, 105(9), 2489-2497. John Wiley and Sons Inc.
The chairs of each of the 8 Special Interest Groups of the Board of Pharmaceutical Sciences of the International Pharmaceutical Federation have compiled opinions with regard to major challenges for the pharmaceutical sciences over the next 5-10 years
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::369afbbf616e074f5eb4ee5ea666dc36
https://doi.org/10.1016/j.xphs.2015.12.001
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje