Zobrazeno 1 - 10
of 53
pro vyhledávání: '"GEN-SHENG WANG"'
Autor:
Brigitte Sonier, Alexander Strom, Gen-Sheng Wang, Christopher Patrick, Jennifer A Crookshank, Majid Mojibian, Amanda J MacFarlane, Fraser W Scott
Publikováno v:
Canadian Journal of Gastroenterology, Vol 25, Iss 6, Pp 327-329 (2011)
Antibodies against the wheat storage globulin Glo-3A from a patient with both type 1 diabetes (T1D) and celiac disease were enriched to identify potential molecular mimicry between wheat antigens and T1D target tissues. Recombinant Glo-3A was used to
Externí odkaz:
https://doaj.org/article/f7dfb079d7464322b1cdaeefd9e76806
Autor:
Guillaume Pelletier, Ivana Kosarac, Sabit Cakmak, Gen Sheng Wang, Cariton Kubwabo, Shabana Siddique, Don Caldwell, Marc Rigden, Karen Leingartner
Publikováno v:
Journal of Applied Toxicology
Tris(2‐ethylhexyl) phosphate (TEHP, CAS no. 78‐42‐2) is a plasticizer and a flame retardant, while di(2‐ethylhexyl) phosphoric acid (DEHPA, CAS no. 298‐07‐7) is an oil additive and extraction solvent. Publicly‐available information on r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c434634a625a2307cd73a930e0363a41
https://pubmed.ncbi.nlm.nih.gov/31884710
https://pubmed.ncbi.nlm.nih.gov/31884710
Autor:
Walid Mottawea, Alain Stintzi, Fraser W. Scott, Christopher Patrick, Gen-Sheng Wang, Lynley D. Pound, Roxanne Vandenbeek, Turki S. Abujamel, Chandra E. Eberhard
Publikováno v:
Diabetes. 64:4135-4147
Cathelicidin antimicrobial peptide (CAMP) is a naturally occurring secreted peptide that is expressed in several organs with pleiotropic roles in immunomodulation, wound healing, and cell growth. We previously demonstrated that gut Camp expression is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce45a471137793affce590679a56c7ea
https://doi.org/10.2337/db15-0788
https://doi.org/10.2337/db15-0788
Autor:
Christopher Patrick, Mahmoud Husseini, Amanda J. MacFarlane, Gen-Sheng Wang, Alexander Strom, Fraser W. Scott, Jennifer A. Crookshank, J. Ariana Noel
Publikováno v:
Endocrinology. 156:3937-3949
Immunoregulatory and regenerative processes are activated in the pancreas during the development of type 1 diabetes (T1D) but are insufficient to prevent the disease. We hypothesized that the induction of cytoprotective heme oxygenase-1 (HO-1) by cob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c46d9e14e506aae87a42aa1b1d866e1
https://doi.org/10.1210/en.2015-1304
https://doi.org/10.1210/en.2015-1304
Publikováno v:
Immunology. 145:417-428
The gut immune system and its modification by diet have been implicated in the pathogenesis of type 1 diabetes (T1D). Therefore, we investigated gut immune status in non-diabetes-prone LEW.1AR1 and diabetes-prone LEW.1AR1-iddm rats and evaluated the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d9ab6a8d110826576c8a8c4cdc4110
https://doi.org/10.1111/imm.12457
https://doi.org/10.1111/imm.12457
Autor:
Majambu Mbikay, Andrew Chen, Fraser W. Scott, Francine Sirois, Charles Gyamera-Acheampong, Gen-Sheng Wang, Peter Rippstein, Michel Chrétien, Janice Mayne
Publikováno v:
Journal of Diabetes. 7:74-84
Background Proprotein convertase subtilisin/kexin-type 9 (PCSK9) downregulates clearance of plasma cholesterol by liver. Its inactivation increases this clearance, reducing cardiovascular risk. However, a lack of PCSK9 could also lead to cholesterol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f675f6c824c0d9330353ba295f3d63ed
https://doi.org/10.1111/1753-0407.12139
https://doi.org/10.1111/1753-0407.12139
Autor:
Gen-Sheng Wang, Dirk Wedekind, Conny Gysemans, Lorella Marselli, Hans-Jürgen Hedrich, Sigurd Lenzen, Yutaka Nakaya, Piero Marchetti, Fraser W. Scott, T Arndt, Jürgen Klempnauer, Chantal Mathieu, Andreas Meyer zu Vilsendorf, Anne Jörns, Nagakatsu Harada
Publikováno v:
Diabetologia; Vol 57
Research on the pathogenesis of type 1 diabetes relies heavily on good animal models. The aim of this work was to study the translational value of animal models of type 1 diabetes to the human situation.We compared the four major animal models of spo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c5d9f05654439b67da06497382547ce
https://doi.org/10.1007/s00125-013-3125-4
https://doi.org/10.1007/s00125-013-3125-4
Autor:
Gen-Sheng Wang
Publikováno v:
Journal of Applied Sciences. 13:4062-4066
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c1e6b41c19989f77c2171e49cd27bdb
https://doi.org/10.3923/jas.2013.4062.4066
https://doi.org/10.3923/jas.2013.4062.4066
Autor:
Martin Kalmokoff, Chandra Eberhard, Mariantonia Maglio, Brigitte Sonier, Stephen P. J. Brooks, Majid Mojibian, Gen-Sheng Wang, David E. Lefebvre, Jennifer A. Crookshank, Fraser W. Scott, Riccardo Troncone, Christopher Patrick, Chris R. J. Kennedy, Philippe Poussier
Publikováno v:
Diabetes
We are exposed to millions of microbial and dietary antigens via the gastrointestinal tract, which likely play a key role in type 1 diabetes (T1D). We differentiated the effects of these two major environmental factors on gut immunity and T1D. Diabet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aad0fef139ca9a1540b26142919404a1
https://doi.org/10.2337/db12-1243
https://doi.org/10.2337/db12-1243
Publikováno v:
Pancreas. 40:229-232
We previously demonstrated that the expression of cellular prion protein (PrPC) in islet [beta]-cells is suppressed in hyperglycemic rats suggesting a major role for PrPC in blood glucose regulation. To further characterize the function of PrPC in gl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd66392983b8413eb698d50f7bd1f54b
https://doi.org/10.1097/mpa.0b013e3181f7e547
https://doi.org/10.1097/mpa.0b013e3181f7e547