Zobrazeno 1 - 10
of 781
pro vyhledávání: '"GEMM"'
Publikováno v:
Cancer Biology & Medicine, Vol 21, Iss 7, Pp 553-570 (2024)
Gastric cancer (GC) is a major cause of cancer-related mortality worldwide. GC is determined by multiple (epi)genetic and environmental factors; can occur at distinct anatomic positions of the stomach; and displays high heterogeneity, with different
Externí odkaz:
https://doaj.org/article/0f26bab976a74c029a4b420ac661447d
Autor:
Marta Piqué-Gili, Carmen Andreu-Oller, Agavni Mesropian, Roger Esteban-Fabró, Marina Bárcena-Varela, Marina Ruiz de Galarreta, Carla Montironi, Iris Martinez-Quetglas, Sarah Cappuyns, Judit Peix, Ieva Keraite, Albert Gris-Oliver, Elisa Fernández-Martínez, Ezequiel Mauro, Miguel Torres-Martin, Jordi Abril-Fornaguera, Katherine E. Lindblad, Diether Lambrechts, Jeroen Dekervel, Swan N. Thung, Daniela Sia, Amaia Lujambio, Roser Pinyol, Josep M. Llovet
Publikováno v:
JHEP Reports, Vol 6, Iss 11, Pp 101212- (2024)
Background & Aims: Transforming growth factor β (TGF-β) plays an oncogenic role in advanced cancer by promoting cell proliferation, metastasis and immunosuppression. PMEPA1 (prostate transmembrane protein androgen induced 1) has been shown to promo
Externí odkaz:
https://doaj.org/article/93d51b39e7c4419c83008f56aa023b9c
Akademický článek
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Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/a9a8996edca849559e3286979818e7ad
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
This review systematically describes the application of in vivo mouse models in studying cutaneous T-cell lymphoma (CTCL), a complex hematological neoplasm. It highlights the diverse research approaches essential for understanding CTCL’s intricate
Externí odkaz:
https://doaj.org/article/eea5fb9e54a5464b902ec87f18c9ab23
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-24 (2023)
Abstract Lung squamous cell carcinoma (LUSC) is associated with high mortality and limited targeted therapies. USP13 is one of the most amplified genes in LUSC, yet its role in lung cancer is largely unknown. Here, we established a novel mouse model
Externí odkaz:
https://doaj.org/article/626e7d518b9846f0ac8bdcb42a97e591
Autor:
Matthew Brown, Alicia Leon, Katarzyna Kedzierska, Charlotte Moore, Hayley L Belnoue‐Davis, Susanne Flach, John P Lydon, Francesco J DeMayo, Annabelle Lewis, Tjalling Bosse, Ian Tomlinson, David N Church
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 10, Pp n/a-n/a (2023)
Abstract High‐risk endometrial cancer has poor prognosis and is increasing in incidence. However, understanding of the molecular mechanisms which drive this disease is limited. We used genetically engineered mouse models (GEMM) to determine the fun
Externí odkaz:
https://doaj.org/article/5c8f6de2c4ae45eeb10187d03d135ae1
Autor:
Nicol Mecozzi, Arianna Nenci, Olga Vera, Ilah Bok, Aimee Falzone, Gina M. DeNicola, Florian A. Karreth
Publikováno v:
RNA Biology, Vol 19, Iss 1, Pp 353-363 (2022)
Circular RNAs (circRNAs) are a class of non-coding RNAs featuring a covalently closed ring structure formed through backsplicing. circRNAs are broadly expressed and contribute to biological processes through a variety of functions. Standard gain-of-f
Externí odkaz:
https://doaj.org/article/4d0722bab6c14d0ebefa963fc0141942
Autor:
Lei, Jie
[ES] Esta tesis presenta un estudio exhaustivo sobre la implementación de una realización eficiente de GEMM en procesadores de bajo consumo y en una plataforma heterogénea de AMD. Esta investigación está inspirada por la creciente demanda de inf
Externí odkaz:
http://hdl.handle.net/10251/212297
Akademický článek
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