Zobrazeno 1 - 10
of 4 881
pro vyhledávání: '"GE LI"'
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Choroidal neovascularization (CNV) is a leading cause of visual impairment in wet age-related macular degeneration (wAMD). Recent investigations have validated the potential of reducing glutamine synthetase (GS) to inhibit neovascularization
Externí odkaz:
https://doaj.org/article/0c5e976d45cf4377a4c68457a251f7f1
Autor:
Ge Li, Fei-Fei She, Cheng-Yu Liao, Zu-Wei Wang, Yi-Ting Wang, Yong-Din Wu, Xiao-Xiao Huang, Cheng-Ke Xie, Hong-Yi Lin, Shun-Cang Zhu, Yin-Hao Chen, Zhen-heng Wu, Jiang-Zhi Chen, Shi Chen, Yan-Ling Chen
Publikováno v:
Cell Death and Disease, Vol 15, Iss 10, Pp 1-15 (2024)
Abstract Resistance to gemcitabine in pancreatic ductal adenocarcinoma (PDAC) leads to ineffective chemotherapy and, consequently, delayed treatment, thereby contributing to poor prognosis. Glycolysis is an important intrinsic reason for gemcitabine
Externí odkaz:
https://doaj.org/article/4bdc36bc2ab14f91b64441e6f98e7ee8
Autor:
Cheng-Ke Xie, Cheng-Yu Liao, Hong-Yi Lin, Yong-Ding Wu, Feng-Chun Lu, Xiao-Xiao Huang, Zu-Wei Wang, Ge Li, Cai-Feng Lin, Jian-Fei Hu, Yin-Hao Chen, Qiao-Wei Li, Li-Qun Chen, Hui-Xing Chen, Shi Chen
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-24 (2024)
Abstract The Nab-paclitaxel combined with gemcitabine (AG) regimen is the main chemotherapy regimen for pancreatic cancer, but drug resistance often occurs. Currently, the ability to promote sensitization in drug-resistant cases is an important clini
Externí odkaz:
https://doaj.org/article/edf2aa10eb904f14b6d7926db16fd850
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-18 (2024)
Abstract Gliomas are aggressive brain tumors associated with poor prognosis and limited treatment options due to their invasive nature and resistance to current therapeutic modalities. Research suggests that exosomal microRNAs have emerged as key pla
Externí odkaz:
https://doaj.org/article/4905402312b541b8940232d50c2890d2
Autor:
Yan Luo, Jingjing Chen, Jinyao Ning, Yuanyuan Sun, Yitong Chai, Fen Xiao, Bixia Huang, Ge Li, Fen Tian, Jie Hao, Qiong Zhang, Jing Zhao, Yanping Li, Hui Li
Publikováno v:
Journal of Ovarian Research, Vol 17, Iss 1, Pp 1-17 (2024)
Abstract Background There has been a significant surge in animal studies of stem cell-derived extracellular vesicles (EVs) therapy for the treatment of premature ovarian failure (POF) but its efficacy remains unknown and a comprehensive and up-to-dat
Externí odkaz:
https://doaj.org/article/062d64d218514f2190b2b2375aeb9ac7
Publikováno v:
ACS Omega, Vol 9, Iss 31, Pp 33574-33593 (2024)
Externí odkaz:
https://doaj.org/article/477e3108834a4861a219556596e02a25
Autor:
Cheng-Yu Liao, Ge Li, Feng-Ping Kang, Cai-Feng Lin, Cheng-Ke Xie, Yong-Ding Wu, Jian-Fei Hu, Hong-Yi Lin, Shun-Cang Zhu, Xiao-Xiao Huang, Jian-Lin Lai, Li-Qun Chen, Yi Huang, Qiao-Wei Li, Long Huang, Zu-Wei Wang, Yi-Feng Tian, Shi Chen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract Pancreatic ductal adenocarcinoma (PDAC) is a devastating cancer with dismal prognosis due to distant metastasis, even in the early stage. Using RNA sequencing and multiplex immunofluorescence, here we find elevated expression of mixed lineag
Externí odkaz:
https://doaj.org/article/3526e9d64b1549558ff7062b029ca9d4
Autor:
Songyang Liu, Ge Li, Xiaomao Yin, Yihan Zhou, Dongmei Luo, Zhenggang Yang, Jin Zhang, Jianfeng Wang
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Clear cell renal cell carcinoma (ccRCC) is a prevalent malignancy with complex heterogeneity within epithelial cells, which plays a crucial role in tumor progression and immune regulation. Yet, the clinical importance of the malignant epithe
Externí odkaz:
https://doaj.org/article/c1633c96e2cc482ba280f7cfb731f008
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 14, Iss 12, Pp 100964- (2024)
Urinary system tumors include malignancies of the bladder, kidney, and prostate, and present considerable challenges in diagnosis and treatment. The conventional therapeutic approaches against urinary tumors are limited by the lack of targeted drug d
Externí odkaz:
https://doaj.org/article/18a007cb5a5e4a268966d434fa574b9a
Autor:
Yang Wang, Kaiwen Li, Siya Yan, Ge Li, Meifang Cheng, Qian Chen, Yuzheng Wu, Dan Wang, Tao Wang
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionThe kidney damage caused by the deposition of uric acid in the kidneys is of urgent need for new treatment drugs due to its complex pathogenesis. Orthosiphon aristatus (Blume) Miq. Also known as C. spicatus, which has a significant therap
Externí odkaz:
https://doaj.org/article/c2daeb5eb90e466795da034f3e33352a