Zobrazeno 1 - 10
of 21
pro vyhledávání: '"GDP, Guanosine diphosphate"'
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 7, Pp 1813-1834 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Ginsenosides are a series of glycosylated triterpenoids which belong to protopanaxadiol (PPD)-, protopanaxatriol (PPT)-, ocotillol (OCT)- and oleanane (OA)-type saponins known as active compounds of Panax genus. They are accumulated in plant roots, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f3ebd6a887266674e75c6007dc0b127
https://doi.org/10.1016/j.apsb.2020.12.017
https://doi.org/10.1016/j.apsb.2020.12.017
Autor:
Iulia Oancea, Andy Wu, Michael A. McGuckin, Sumaira Z. Hasnain, Rabina Giri, John D. Hooper, Veronika Schreiber, Brett C McWhinney, Julie M. Davies, Jakob Begun, Yonghua Sheng, David P. Fairlie, Saleh Y. Alabbas, Gregor Kijanka, Yaowu He, Ramya Movva, Andrew J. Lucke, Timothy H. Florin
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 33-53 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Chronic bowel inflammation increases the risk of colon cancer; colitis-associated cancer (CAC). Thiopurine treatments are associated with a reduction in dysplasia and CAC in inflammatory bowel disease (IBD). Abnormal Wnt/β-catenin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f601ccce23a182b6171ce5a7c5598ec
http://www.sciencedirect.com/science/article/pii/S2352345X20300886
http://www.sciencedirect.com/science/article/pii/S2352345X20300886
Publikováno v:
The Journal of Biological Chemistry
The human dedicator of cytokinesis (DOCK) family consists of 11 structurally conserved proteins that serve as atypical RHO guanine nucleotide exchange factors (RHO GEFs). These regulatory proteins act as mediators in numerous cellular cascades that p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8a6616905efc2a2ef77da8d684aca0b
http://europepmc.org/articles/PMC8063744
http://europepmc.org/articles/PMC8063744
Autor:
Tessa R. Young, Evelyne Deery, Anastasia Cooke, Martin J. Warren, Deenah Osman, Nigel J. Robinson
Publikováno v:
Biochimica et Biophysica Acta. Molecular Cell Research
Vitamin B12, cobalamin, is a cobalt-containing ring-contracted modified tetrapyrrole that represents one of the most complex small molecules made by nature. In prokaryotes it is utilised as a cofactor, coenzyme, light sensor and gene regulator yet ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ace2dec5de2d9cde658800a4c92af8b
http://europepmc.org/articles/PMC7689651
http://europepmc.org/articles/PMC7689651
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 99-115 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 99-115 (2021)
Background & Aims Chronic amino acid (AA) deficiency, as in kwashiorkor, reduces the size of the pancreas through an effect on mammalian target of rapamycin complex 1 (mTORC1). Because of the physiological importance of AAs and their role as a substr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bdfa7077fd78998f54db32a754523b3
https://pubmed.ncbi.nlm.nih.gov/32735995
https://pubmed.ncbi.nlm.nih.gov/32735995
Autor:
Chuan Han Jonathan Foo, Shazib Pervaiz
Publikováno v:
Redox Biology, Vol 25, Iss, Pp-(2019)
Redox Biology
Redox Biology
RAS proteins are critical regulators of signaling networks controlling diverse cellular functions such as cell proliferation and survival and its mutation are among the most powerful oncogenic drivers in human cancers. Despite intense efforts, direct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c11cd3c78529b5f4eae7369f41a3e411
http://www.sciencedirect.com/science/article/pii/S2213231718311558
http://www.sciencedirect.com/science/article/pii/S2213231718311558
Publikováno v:
Biochemical Pharmacology
Biochemical pharmacology 167 (2019): 13–26. doi:10.1016/j.bcp.2019.06.001
info:cnr-pdr/source/autori:Catara, Giuliana; Corteggio, Annunziata; Valente, Carmen; Grimaldi, Giovanna; Palazzo, Luca/titolo:Targeting ADP-ribosylation as an antimicrobial strategy/doi:10.1016%2Fj.bcp.2019.06.001/rivista:Biochemical pharmacology/anno:2019/pagina_da:13/pagina_a:26/intervallo_pagine:13–26/volume:167
Biochemical pharmacology 167 (2019): 13–26. doi:10.1016/j.bcp.2019.06.001
info:cnr-pdr/source/autori:Catara, Giuliana; Corteggio, Annunziata; Valente, Carmen; Grimaldi, Giovanna; Palazzo, Luca/titolo:Targeting ADP-ribosylation as an antimicrobial strategy/doi:10.1016%2Fj.bcp.2019.06.001/rivista:Biochemical pharmacology/anno:2019/pagina_da:13/pagina_a:26/intervallo_pagine:13–26/volume:167
Graphical abstract
ADP-ribosylation (ADPr) is an ancient reversible modification of cellular macromolecules controlling major biological processes as diverse as DNA damage repair, transcriptional regulation, intracellular transport, immune and s
ADP-ribosylation (ADPr) is an ancient reversible modification of cellular macromolecules controlling major biological processes as diverse as DNA damage repair, transcriptional regulation, intracellular transport, immune and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b75a92558b9e6288c6602ac3398b2c6
https://pubmed.ncbi.nlm.nih.gov/31176616
https://pubmed.ncbi.nlm.nih.gov/31176616
Autor:
Mohammed Iraqui Houssaini, Samir Atmani, Ihssane El Bouchikhi, Khadija Belhassan, Karim Ouldim, Fatima Zohra Moufid, Laila Bouguenouch, Imane Samri
Publikováno v:
International Journal of Pediatrics & Adolescent Medicine
International Journal of Pediatrics and Adolescent Medicine, Vol 3, Iss 4, Pp 133-142 (2016)
International Journal of Pediatrics and Adolescent Medicine, Vol 3, Iss 4, Pp 133-142 (2016)
Noonan syndrome is a common autosomal dominant disorder characterized by short stature, congenital heart disease and facial dysmorphia with an incidence of 1/1000 to 2500 live births. Up to now, several genes have been proven to be involved in the di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b30e90f717f374a42b7ecb6fb885f044
https://doi.org/10.1016/j.ijpam.2016.06.003
https://doi.org/10.1016/j.ijpam.2016.06.003
Autor:
Liping Tian, Suzy A. A. Comhair, James Hiznay, Jarrod W. Barnes, Jacqueline Loftis, Raed A. Dweik, Mark E. Lauer
Publikováno v:
MethodsX
Graphical abstract
The building blocks of simple and complex oligosaccharides, termed sugar nucleotides, are often overlooked for their role in metabolic diseases and may hold the key to the underlying disease pathogenesis. Multiple reasons may
The building blocks of simple and complex oligosaccharides, termed sugar nucleotides, are often overlooked for their role in metabolic diseases and may hold the key to the underlying disease pathogenesis. Multiple reasons may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::879ff078430224727d3ba8f2b4858b03
Autor:
Diana D. H. Thomas, Michelle M. Cooley, Scott W. Messenger, Fred S. Gorelick, Michelle A. Falkowski, Luis A. Fernandez, Guy E. Groblewski, Benjamin K. August, Elaina K. Jones
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 1, Iss 6, Pp 695-709 (2015)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims: Pancreatic acinar cells have an expanded apical endosomal system, the physiologic and pathophysiologic significance of which is still emerging. Phosphatidylinositol-3,5-bisphosphate [PI(3,5)P2] is an essential phospholipid generate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e5e6298034e5ed01785c0f1e3ea0524