Sex differences in offspring neurodevelopment, cognitive performance and microglia morphology associated with maternal diabetes: Putative targets for insulin therapy

Autor: Raquel G. Correia, Alexandra F. Cruz, Joana Martins, Filipa I. Baptista, Matilde S. Rodrigues, Fabio J. Sousa, Catarina Gomes, António F. Ambrósio

Publikováno v: Brain, Behavior, & Immunity-Health
Brain, Behavior, & Immunity-Health, Vol 5, Iss, Pp 100075-(2020)

Diabetes during pregnancy has been shown to affect the central nervous system (CNS) of the offspring, resulting in short- and long-term adverse effects. Children of diabetic mothers are more likely to develop cognitive impairment, also having increas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beb8d57b499e88ef4ad7ac8e050ab14d
http://europepmc.org/articles/PMC8474564

Prenatal vitamin C deficiency results in differential levels of oxidative stress during late gestation in foetal guinea pig brains

Autor: Maya Devi Paidi, Pernille Tveden-Nyborg, Jens Lykkesfeldt, Janne G. Schjoldager

Publikováno v: Redox Biology, Vol 2, Iss C, Pp 361-367 (2014)
Redox Biology

Antioxidant defences are comparatively low during foetal development making the brain particularly susceptible to oxidative stress during antioxidant deficiencies. The brain is one of the organs containing the highest concentration of vitamin C (VitC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e529e73762eba38bdbe6deb6f4f282b4

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Interaction between mono-(2-ethylhexyl) phthalate and retinoic acid alters Sertoli cell development during fetal mouse testis cord morphogenesis.

Autor: Alhasnani MA; Department of Pathology and Laboratory Medicine, Brown University, Box G-E5, Providence, RI 02912, USA., Loeb S; Department of Pathology and Laboratory Medicine, Brown University, Box G-E5, Providence, RI 02912, USA., Hall SJ; Department of Pathology and Laboratory Medicine, Brown University, Box G-E5, Providence, RI 02912, USA., Caruolo Z; Department of Pathology and Laboratory Medicine, Brown University, Box G-E5, Providence, RI 02912, USA., Simmonds F; Department of Pathology and Laboratory Medicine, Brown University, Box G-E5, Providence, RI 02912, USA., Solano AE; Department of Pathology and Laboratory Medicine, Brown University, Box G-E5, Providence, RI 02912, USA., Spade DJ; Department of Pathology and Laboratory Medicine, Brown University, Box G-E5, Providence, RI 02912, USA.

Publikováno v: Current research in toxicology [Curr Res Toxicol] 2022 Sep 21; Vol. 3, pp. 100087. Date of Electronic Publication: 2022 Sep 21 (Print Publication: 2022).

Sex differences in offspring neurodevelopment, cognitive performance and microglia morphology associated with maternal diabetes: Putative targets for insulin therapy.

Autor: Sousa FJ; Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, Coimbra, Portugal.; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Portugal., Correia RG; Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, Coimbra, Portugal.; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Portugal., Cruz AF; Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, Coimbra, Portugal.; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Portugal., Martins JM; Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, Coimbra, Portugal.; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Portugal., Rodrigues MS; Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, Coimbra, Portugal.; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Portugal., Gomes CA; Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, Coimbra, Portugal.; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Portugal., Ambrósio AF; Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, Coimbra, Portugal.; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Portugal., Baptista FI; Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, Coimbra, Portugal.; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Portugal.

Publikováno v: Brain, behavior, & immunity - health [Brain Behav Immun Health] 2020 Apr 19; Vol. 5, pp. 100075. Date of Electronic Publication: 2020 Apr 19 (Print Publication: 2020).