Zobrazeno 1 - 10
of 109
pro vyhledávání: '"GC B cells"'
Autor:
Yue Liang, HanChen Wang, Noé Seija, Yun Hsiao Lin, Lin Tze Tung, Javier M. Di Noia, David Langlais, Anastasia Nijnik
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionBAP1 is a deubiquitinase (DUB) of the Ubiquitin C-terminal Hydrolase (UCH) family that regulates gene expression and other cellular processes, through its direct catalytic activity on the repressive epigenetic mark histone H2AK119ub, as w
Externí odkaz:
https://doaj.org/article/2d7114a19c9f4754966093185d4ffaf5
Autor:
Feifan Zhu, Wenwen Zheng, Yiyan Gong, Jinyuan Zhang, Yihan Yu, Jixian Zhang, Mengjun Liu, Fei Guan, Jiahui Lei
Publikováno v:
Vaccines, Vol 12, Iss 7, p 729 (2024)
Vaccines are the most effective and feasible way to control pathogen infection. Helminths have been reported to jeopardize the protective immunity mounted by several vaccines. However, there are no experimental data about the effect of helminth infec
Externí odkaz:
https://doaj.org/article/1111e613ba604910b41e6480eafa35e2
Autor:
Ursula Rambold, Stefanie Sperling, Zakir Chew, Yan Wang, Beatrix Steer, Krisztina Zeller, Lothar J. Strobl, Ursula Zimber-Strobl, Heiko Adler
Publikováno v:
Cells, Vol 12, Iss 24, p 2780 (2023)
CD30-positive germinal center (GC)-derived B cell lymphomas are frequently linked to Epstein–Barr Virus (EBV) infection. However, a suitable animal model for the investigation of the interplay between γ-herpesvirus and host cells in B cell pathoge
Externí odkaz:
https://doaj.org/article/555c81fab2d649c5ab4460a9bcb17c64
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The germinal center (GC) reaction is a key process during an adaptive immune response to T cell specific antigens. GCs are specialized structures within secondary lymphoid organs, in which B cell proliferation, somatic hypermutation and antibody affi
Externí odkaz:
https://doaj.org/article/55ebb4d04f424abda17ff4eadfdfd995
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Alessandra Noto, Madeleine Suffiotti, Victor Joo, Antonio Mancarella, Francesco A. Procopio, Guy Cavet, Yvonne Leung, Jean-Marc Corpataux, Matthias Cavassini, Agostino Riva, Leonidas Stamatatos, Raphael Gottardo, Adrian B. McDermott, Richard A. Koup, Craig Fenwick, Matthieu Perreau, Giuseppe Pantaleo
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Optimal T follicular helper (Tfh) cells function is important to promote the development of germinal centers and maturation of high affinity antigen-specific B cells. We have found that the expression of CXCR3 defines distinct Tfh subsets: CXCR3+ Th1
Externí odkaz:
https://doaj.org/article/f7bc6d2291a744dca296140e03ea8ac7
Autor:
Madelene W. Dahlgren, Adam W. Plumb, Kristoffer Niss, Katharina Lahl, Søren Brunak, Bengt Johansson-Lindbom
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Type I interferons (IFNs) are essential for antiviral immunity, appear to represent a key component of mRNA vaccine-adjuvanticity, and correlate with severity of systemic autoimmune disease. Relevant to all, type I IFNs can enhance germinal center (G
Externí odkaz:
https://doaj.org/article/506d2b0c10234ec297ecb6f6a11d3519
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-10 (2020)
Abstract Background The mechanisms involved in the pathogenesis of autoimmune disorders, including systemic lupus erythematosus (SLE), have not been fully elucidated. Some of these mechanisms involve epigenetic regulation of gene expression. The hist
Externí odkaz:
https://doaj.org/article/c110bc951a9641cb9eab816f75bedbcf
Autor:
Kathleen Santamaria, Fabienne Desmots, Simon Leonard, Gersende Caron, Marion Haas, Céline Delaloy, Fabrice Chatonnet, Delphine Rossille, Amandine Pignarre, Céline Monvoisin, Marine Seffals, Claire Lamaison, Michel Cogné, Karin Tarte, Thierry Fest
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
B cell affinity maturation occurs in the germinal center (GC). Light-zone (LZ) GC B cells (BGC-cells) interact with follicular dendritic cells (FDCs) and compete for the limited, sequential help from T follicular helper cells needed to escape from ap
Externí odkaz:
https://doaj.org/article/2a37c82726ad4a66bf158171a125e426
Autor:
África Martínez-Blanco, Marilú Domínguez-Pantoja, María Botía-Sánchez, Sonia Pérez-Cabrera, Nerea Bello-Iglesias, Paula Carrillo-Rodríguez, Natividad Martin-Morales, Antonio Lario-Simón, María M. Pérez-Sánchez-Cañete, Laura Montosa-Hidalgo, Salvador Guerrero-Fernández, Victoria M. Longobardo-Polanco, Sandra Redondo-Sánchez, Alberto Cornet-Gomez, María Torres-Sáez, Ana Fernández-Ibáñez, Laura Terrón-Camero, Eduardo Andrés-León, Francisco O’Valle, Ramón Merino, Mercedes Zubiaur, Jaime Sancho
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The absence of the mouse cell surface receptor CD38 in Cd38−/− mice suggests that this receptor acts as a positive regulator of inflammatory and autoimmune responses. Here, we report that, in the context of the chronic graft-versus-host disease (
Externí odkaz:
https://doaj.org/article/a00bd329d702410b9ebcd3e172e7f1ee