ADMET-Evaluation, Pharmacokinetics, Drug-likeness and Medicinal Chemistry of GCMS Identified Bioactive Compounds of Moringa oleifera Natural-Ripened-Dried Methanolic Pod Extract (MOMPE) as a Potential Source of Natural Drug Frontrunner for Next Generation

Autor: R. Jayakumararaj, J. King Immanuel, GC. Abraham, G Grace Lydial Pushpalatha, S. Ramya, Sanyam Gandhi, Mohamed Ali Seyed, S. Sutha, N. Senthilkumar, N. Kavitha, A. Jeevalatha, K. Suganandam, C. Kandeepan

Publikováno v: Journal of Drug Delivery and Therapeutics. 12:65-85

Over centuries, Moringa oleifera has been used as an integral part of Ayurveda, Siddha and Unani systems of medicine, besides this miracle tree has a wide range of nutritional and bioactive compounds, including proteins, essential amino acids, carboh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4603f97d125c400f698e5527c9cf1fd6
https://doi.org/10.22270/jddt.v12i6.5668

Profile of Phytochemicals and GCMS Analysis of Bioactive Compounds in Natural Dried-Seed Removed Ripened Pods Methanolic Extracts of Moringa oleifera

Autor: R. Jayakumararaj, GC. Abraham, G Grace Lydial Pushpalatha, S. Ramya, Sanyam Gandhi, Mohamed Ali Seyed, S. Sutha, N. Senthilkumar, N. Kavitha, C. Kandeepan, A. Jeevalatha, K. Suganandam

Publikováno v: Journal of Drug Delivery and Therapeutics. 12:133-141

Moringa oleifera has been reported to be the store-house of wide range of bioactive compounds. Most commonly used plant part has been the leaves which are reported to be rich in Vitamins, Carotenoids, Polyphenols, Phenolic Acids, Flavonoids Alkaloids

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e4e5f2fd62710fa41ca16712606e3b27
https://doi.org/10.22270/jddt.v12i5-s.5657

Artificial Intelligence and Machine Learning approach based in-silico ADME-Tox and Pharmacokinetic Profile of α-Linolenic acid from Catharanthus roseus (L.) G. Don

Autor: R. Jayakumararaj, C Kandeepan, T. Ponrathy, GC. Abraham, S. Balamurugan, T. Loganathan, Devaraj Aruna, G. Grace Lydial Pushpalatha, C. Soorya, S. Ramya

Publikováno v: Journal of Drug Delivery and Therapeutics. 12:96-109

Current craze and concomitant rise of Artificial Intelligence and Machine Learning (AI&ML) in the post-COVID-era holds significant contribution to Drug Design and Development. Along with IoT, AI&ML has reduced human interface and improved the Quality

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9f229ecf1591a4092e882d5dff403719
https://doi.org/10.22270/jddt.v12i2-s.5274

ADME-Tox profile of Cuminaldehyde (4-Isopropylbenzaldehyde) from Cuminum cyminum seeds for potential biomedical applications.

Autor: Ramya, S., Loganathan, T., Chandran, M., Priyanka, R., Kavipriya, K., Pushpalatha G., Grace Lydial, Devaraj, Aruna, GC., Abraham, Jayakumararaj, R.

Publikováno v: Journal of Drug Delivery & Therapeutics; 2022 Supplement, Vol. 12, p127-141, 15p

Effect of biogenic silver nanocubes on matrix metalloproteinases 2 and 9 expressions in hyperglycemic skin injury and its impact in early wound healing in streptozotocin-induced diabetic mice.

Autor: Krishnan N; Department of Microbiology, School of Life Sciences, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India. Electronic address: knknatarajan@gmail.com., Velramar B; Department of Microbiology, School of Life Sciences, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India; Department of Biotechnology, School of Biosciences, Periyar University, Salem, Tamil Nadu, India., Ramatchandirin B; Department of Biochemistry, School of Life Sciences, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India., Abraham GC; Department of Botany, The American College, Madurai, Tamil Nadu, India., Duraisamy N; Department of Microbiology, School of Life Sciences, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India., Pandiyan R; Department of Microbiology, School of Life Sciences, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India; Department of Civil Engineering, Yeungnam University, Gyeongsan, Republic of Korea., Velu RK; Department of Microbiology, School of Life Sciences, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India.

Publikováno v: Materials science & engineering. C, Materials for biological applications [Mater Sci Eng C Mater Biol Appl] 2018 Oct 01; Vol. 91, pp. 146-152. Date of Electronic Publication: 2018 May 05.