Zobrazeno 1 - 10
of 52
pro vyhledávání: '"GC, gastric cancer"'
Autor:
Yunan Han, Zhi-Feng Miao, Min-Jiao Pang, Jason C. Mills, Mahliyah Adkins-Threats, Ramon U. Jin, Joseph Burclaff, Luciana H. Osaki, Zhenning Wang
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
The stomach is a complex and physiologically necessary organ, yet large differences in physiology between mouse and human stomachs have impeded translation of physiological discoveries and drug screens performed using murine gastric tissues. Gastric
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 910-928 (2021)
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 910-928 (2021)
Graphical abstract
Circular RNAs (circRNAs) are a very interesting class of conserved single-stranded RNA molecules derived from exonic or intronic sequences by precursor mRNA back-splicing. Unlike canonical linear RNAs, circRNAs form covalently
Circular RNAs (circRNAs) are a very interesting class of conserved single-stranded RNA molecules derived from exonic or intronic sequences by precursor mRNA back-splicing. Unlike canonical linear RNAs, circRNAs form covalently
Autor:
Christina Falkeis-Veits, Victoria Neumeyer, Elisabeth Kremmer, Anna Brutau-Abia, Nicole Pfarr, Michael Allgäuer, Raquel Mejías-Luque, Markus Gerhard, Wilko Weichert, Michael Vieth
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cell. Mol. Gast. Hept. 11, 1071-1094 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 1071-1094 (2021)
Cell. Mol. Gast. Hept. 11, 1071-1094 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 1071-1094 (2021)
Background & Aims RING finger protein 43 (RNF43) is a tumor suppressor that frequently is mutated in gastric tumors. The link between RNF43 and modulation of Wingless-related integration site (WNT) signaling has not been shown clearly in the stomach.
Autor:
Yi-Chao Zheng, Hong-Min Liu, Ouwen Li, Jun-Wei Wang, Zhenhe Suo, Fengyu Qi, Wen-Ting Kang, Pengxing He, Zhi-Ru Wang, Yinghua You
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 694-707 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 694-707 (2021)
Targeting immune checkpoints such as programmed cell death protein 1 (PD-1) and programmed death ligand-1 (PD-L1) have been approved for treating melanoma, gastric cancer (GC) and bladder cancer with clinical benefit. Nevertheless, many patients fail
Publikováno v:
CMGH Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 857-874 (2022)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 857-874 (2022)
Cellular and Molecular Gastroenterology and Hepatology
The gastrointestinal (GI) tract is home to a complex and dynamic community of microorganisms, comprising bacteria, archaea, viruses, yeast, and fungi. It is widely accepted that human health is shaped by these microbes and their collective microbial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e9dcd3a78e3ecd5872b33abf096d79e
https://hdl.handle.net/10067/1873270151162165141
https://hdl.handle.net/10067/1873270151162165141
Publikováno v:
Translational Oncology
Translational Oncology, Vol 14, Iss 11, Pp 101199-(2021)
Translational Oncology, Vol 14, Iss 11, Pp 101199-(2021)
Highlights • The molecular mechanism of miR-205-3p in inhibiting the proliferation and invasion of GC was elucidated in animal and cell experiments. • The molecular mechanism of miR-205-3p in induction of senescence by inhibiting CXCL11 and Akt p
Autor:
Ryohei Matsui, Satoshi Kurokawa, Satoru Takayama, Hisanori Kani, Tsuyoshi Fujiwara, Toru Imagami, Masaki Sakamoto, Taku Hattori
Publikováno v:
International Journal of Surgery Case Reports
Highlights • The optimal management for synchronous advanced cancer remains controversial. • Multidisciplinary treatment strategies are important for synchronous advanced cancer. • Combined laparoscopic and robotic surgery allows minimally inva
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 2329-2346 (2021)
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 2329-2346 (2021)
Graphical abstract
The progress of artificial intelligence algorithms and massive data provide new ideas and choices for individual mortality risk prediction for cancer patients. The current research focused on depict immune gene related regulat
The progress of artificial intelligence algorithms and massive data provide new ideas and choices for individual mortality risk prediction for cancer patients. The current research focused on depict immune gene related regulat
Autor:
Spencer G. Willet
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 5, Pp 1545-(2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Helicobacter pylori infection in humans typically begins with colonization of the gastric antrum. The initial Th1 response occasionally coincides with an increase in gastrin secretion. Subsequently, the gastritis segues to chronic a
Autor:
Zhuonan Zhuang, Teng Wu, Huai-Qiang Ju, Li-Fen Zhou, Jie-Chun Lin, Ting Dai, Lei Lu, Shuai Li, Zexian Liu
Publikováno v:
Redox Biology
Redox Biology, Vol 18, Iss, Pp 246-255 (2018)
Redox Biology, Vol 18, Iss, Pp 246-255 (2018)
Overcoming oxidative stress is a critical step for tumor growth and metastasis, however the underlying mechanisms in gastric cancer remain unclear. In this study, we found that overexpression of nicotinamide nucleotide transhydrogenase (NNT) was asso