Zobrazeno 1 - 10
of 456
pro vyhledávání: '"GATA-2"'
Publikováno v:
Infection and Drug Resistance, Vol Volume 14, Pp 1311-1317 (2021)
Yingying Shen,1 Yuzhu Li,2 Hangchao Li,2 Qi Liu,2 Huijie Dong,2 Bo Wang,1 Baodong Ye,1 Shenyun Lin,1 Yiping Shen,1 Dijiong Wu1 1Department of Hematology, First Affiliated Hospital of Zhejiang Chinese Medical University, Zhejiang Provincial Hospital o
Externí odkaz:
https://doaj.org/article/78d32c42adc447d3a9636d1507dc61aa
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Dengue virus (DENV) infection can cause either self-limited dengue fever or hemorrhagic complications. Low platelet count is one of the manifestations of dengue fever. Megakaryocytes are the sole producers of platelets. However, the role of both host
Externí odkaz:
https://doaj.org/article/199140e61a11466591d67c1b5e873ad4
Autor:
Daniela Palheiro Mendes-de-Almeida, Francianne Gomes Andrade, Gustavo Borges, Filipe V. dos Santos-Bueno, Iracema F. Vieira, Luana Kelly M. da S. da Rocha, Daniella A. Mendes-da-Cruz, Rosely M. Zancopé-Oliveira, Rodrigo T. Calado, Maria S. Pombo-de-Oliveira
Publikováno v:
BMC Medical Genetics, Vol 20, Iss 1, Pp 1-6 (2019)
Abstract Background GATA2 is a transcription factor that is a critical regulator of gene expression in hematopoietic cells. GATA2 deficiency presents with multi-lineage cytopenia, mycobacterial, fungal and viral infections. Patients with GATA2 mutati
Externí odkaz:
https://doaj.org/article/58c6757d702547f5801c05c609ab3b63
Autor:
Katsumura, Koichi R., Mehta, Charu, Hewitt, Kyle J., Soukup, Alexandra A., de Andrade, Isabela Fraga, Ranheim, Erik A., Johnson, Kirby D., Bresnick, Emery H.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2018 Oct . 115(43), E10109-E10118.
Externí odkaz:
https://www.jstor.org/stable/26532385
Autor:
Paul, Angelika C., Rosenthal, Nadia
Publikováno v:
The Journal of Cell Biology, 2002 Feb . 156(4), 751-760.
Externí odkaz:
https://www.jstor.org/stable/1620968
Autor:
Charu Mehta, Kirby D. Johnson, Xin Gao, Irene M. Ong, Koichi R. Katsumura, Skye C. McIver, Erik A. Ranheim, Emery H. Bresnick
Publikováno v:
Cell Reports, Vol 20, Iss 12, Pp 2966-2979 (2017)
Hematopoietic development requires the transcription factor GATA-2, and GATA-2 mutations cause diverse pathologies, including leukemia. GATA-2-regulated enhancers increase Gata2 expression in hematopoietic stem/progenitor cells and control hematopoie
Externí odkaz:
https://doaj.org/article/5f5db142b9614d63809ec53cb53732d3
Autor:
Nadwodney, Martin Aleksander
The way to cure a given illness is to understand the genetic components which contributed to its development within a given patient. Using the Xavier Method, a pie chart was created on Microsoft Excel which specified all the pathogenic proteins assoc
Autor:
Matthew Collin, Dirk Lebrecht, Eirini Trompouki, Emilia J Kozyra, Brigitte Strahm, Valerie de Haas, Sushree S. Sahoo, Owen P. Smith, Riccardo Masetti, Christian Flotho, Charlotte M. Niemeyer, Marta Derecka, Marco Tartaglia, Markus Schmugge, Krisztián Kállay, Rebecca K Voss, Henrik Hasle, Miriam Erlacher, Christian Klemann, Gudrun Göhring, Ester Mejstrikova, Marek Ussowicz, Hauke Busch, Preeti Singh, Barbara De Moerloose, Enikoe Amina Szvetnik, Marcin W. Wlodarski, Patrick Metzger, Lucia Pedace, Shinsuke Hirabayashi, Michael Dworzak, Emma C. Morris, Albert Català, Ramunė Pasaulienė, Jan Starý, Stylianos Lefkopoulos, Franco Locatelli, Victor B Pastor, Melanie Boerries
Publikováno v:
Leukemia
Kozyra, E J, Pastor, V B, Lefkopoulos, S, Sahoo, S S, Busch, H, Voss, R K, Erlacher, M, Lebrecht, D, Szvetnik, E A, Hirabayashi, S, Pasaulienė, R, Pedace, L, Tartaglia, M, Klemann, C, Metzger, P, Boerries, M, Catala, A, Hasle, H, de Haas, V, Kállay, K, Masetti, R, De Moerloose, B, Dworzak, M, Schmugge, M, Smith, O, Starý, J, Mejstrikova, E, Ussowicz, M, Morris, E, Singh, P, Collin, M, Derecka, M, Göhring, G, Flotho, C, Strahm, B, Locatelli, F, Niemeyer, C M, Trompouki, E, Wlodarski, M W & European Working Group of MDS in Childhood (EWOG-MDS) 2020, ' Synonymous GATA2 mutations result in selective loss of mutated RNA and are common in patients with GATA2 deficiency ', Leukemia, vol. 34, no. 10, pp. 2673-2687 . https://doi.org/10.1038/s41375-020-0899-5
LEUKEMIA
Kozyra, E J, Pastor, V B, Lefkopoulos, S, Sahoo, S S, Busch, H, Voss, R K, Erlacher, M, Lebrecht, D, Szvetnik, E A, Hirabayashi, S, Pasaulienė, R, Pedace, L, Tartaglia, M, Klemann, C, Metzger, P, Boerries, M, Catala, A, Hasle, H, de Haas, V, Kállay, K, Masetti, R, De Moerloose, B, Dworzak, M, Schmugge, M, Smith, O, Starý, J, Mejstrikova, E, Ussowicz, M, Morris, E, Singh, P, Collin, M, Derecka, M, Göhring, G, Flotho, C, Strahm, B, Locatelli, F, Niemeyer, C M, Trompouki, E, Wlodarski, M W & European Working Group of MDS in Childhood (EWOG-MDS) 2020, ' Synonymous GATA2 mutations result in selective loss of mutated RNA and are common in patients with GATA2 deficiency ', Leukemia, vol. 34, no. 10, pp. 2673-2687 . https://doi.org/10.1038/s41375-020-0899-5
LEUKEMIA
Deficiency of the transcription factor GATA2 is a highly penetrant genetic disorder predisposing to myelodysplastic syndromes (MDS) and immunodeficiency. It has been recognized as the most common cause underlying primary MDS in children. Triggered by
Autor:
Scherzer, Clemens R., Grass, Jeffrey A., Liao, Zhixiang, Pepivani, Imelda, Zheng, Bin, Eklund, Aron C., Ney, Paul A., Ng, Juliana, McGoldrick, Meghan, Mollenhauer, Brit, Bresnick, Emery H., Schlossmacher, Michael G.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2008 Aug 01. 105(31), 10907-10912.
Externí odkaz:
https://www.jstor.org/stable/25463260
Publikováno v:
Allergology International, Vol 58, Iss 1, Pp 21-28 (2009)
Basophils and mast cells are major players in the progression of allergic disorders. Although both cell types originate from hematopoietic stem cells, their lineage commitment pathways and mechanisms have been unsolved issues in hematology. Recent ad
Externí odkaz:
https://doaj.org/article/ff04453fce4140209922a5a8f2ad15b0