Zobrazeno 1 - 10 of 25 pro vyhledávání: '"GARY R. ERDMANN"'
1
A comparison of red blood cell thiopurine metabolites in children with acute lymphoblastic leukemia who received oral mercaptopurine twice daily or once daily: A Pediatric Oncology Group study (now The Children's Oncology Group)
Autor: S. Sterikoff, Gary R. Erdmann, Bruce Bostrom, Bruce M. Camitta, J J Shuster, G.N. Brockway, Beverly Bell
Publikováno v: Pediatric Blood & Cancer. 43:105-109
Introduction. Mercaptopurine is an important antimetabolite for treatment of childhood acute lymphoblastic leukemia (ALL). It has been prescribed to be given daily without therapeutic monitoring of drug levels. After first-pass metabolism by hepatic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d2ba925567989330d2aaf0f62d09fd
https://doi.org/10.1002/pbc.20089
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3
Plasma pharmacokinetics and cerebrospinal fluid penetration of thioguanine in children with acute lymphoblastic leukemia: a collaborative Pediatric Oncology Branch, NCI, and Children's Cancer Group study
Autor: Robert F. Murphy, Linda C. Stork, Ray Hutchinson, Frank M. Balis, John S. Holcenberg, Bruce Bostrom, Elizabeth S. Lowe, Janet Franklin, Brenda J. Kitchen, Gregory H. Reaman, William Woods, Brigitte C. Widemann, Gary R. Erdmann, Peter C. Adamson
Publikováno v: Cancer Chemotherapy and Pharmacology. 47:199-205
PURPOSE In preclinical studies, thioguanine (TG) has been shown to be more potent than the standard acute lymphoblastic leukemia (ALL) maintenance agent, mercaptopurine (MP), suggesting that TG may be more efficacious than MP in the treatment of chil
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efcbe9c6f40e4fccd826b7d7d63112d5
https://doi.org/10.1007/s002800000229
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4
[Untitled]
Autor: Gary R. Erdmann, G S Giebink, Daniel M. Canafax, Henry Q. Russlie, Steven K. Juhn, Michael J. Lovdahl, G. H. Jossart
Publikováno v: Pharmaceutical Research. 11:860-864
Antimicrobial treatment failures in children with acute otitis media and concomitant viral respiratory tract infection prompted us to study the effects of influenza A virus infection on middle ear antimicrobial drug penetration. Using a chinchilla mo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::77a897303d5c27a0db356e1821f269cd
https://doi.org/10.1023/a:1018933925707
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5
[Untitled]
Autor: Henry Q. Russlie, Gary R. Erdmann, Daniel M. Canafax, G. Scott Giebink, Michael J. Lovdahl, Chap T. Le
Publikováno v: Pharmaceutical Research. 11:855-859
We compared two models of acute otitis media that estimate middle ear antimicrobial pharmacokinetics. Using a crossover study design, we compared a systemic drug administration model with a diffusion model we devised that measures the disappearance o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::99ec4c9b2d383711644bef8b2fa8f183
https://doi.org/10.1023/a:1018981808868
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6
Reversed-phase high-performance liquid chromatographic approach to determine total lymphocyte concentrations of 6-thioguanine, methylmercaptopurine and methylthioguanine in humans
Autor: Jeff C. Steury, Daniel M. Canafax, Bruce Bostrom, Richard J. Stafford, Gary R. Erdmann, Bruce Carleton
Publikováno v: Europe PubMed Central
A reversed-phase high-performance liquid chromatographic (HPLC) procedure was developed to quantify intracellular lymphocyte 6-thioguanine, methylmercaptopurine and methylthioguanine. The free base of each metabolite was obtained by acid hydrolysis,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5310cb848b786cfb339e4ae16034e183
https://doi.org/10.1016/0378-4347(91)80441-e
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7
High Performance Liquid Chromatographic Analysis of Amoxicillin in Microliter Volumes of Chinchilla Middle Ear Effusion and Plasma
Autor: Daniel M. Canafax, G S Giebink, Gary R. Erdmann, K. Walker
Publikováno v: Journal of Liquid Chromatography. 13:3339-3350
A reversed-phase high-performance liquid chromatographic procedure was developed to analyze 75 μ/m1 volumes of chinchilla middle ear effusion and plasma for amoxicillin. The small sample volumes were dictated by the chinchilla model we use to study
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f90b4036c5ac41dd52c65d522dc8111e
https://doi.org/10.1080/01483919008049105
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8
Azathioprine Metabolism: Pharmacokinetics of 6-Mercaptopurine, 6-Thiouric Acid and 6-Thioguanine Nucleotides in Renal Transplant Patients
Autor: Daniel M. Canafax, Arthur J. Matas, Scott A. Gruber, Gary L. C. Chan, Gary R. Erdmann
Publikováno v: The Journal of Clinical Pharmacology. 30:358-363
Despite extensive clinical experience with azathioprine (AZA), the disposition of various AZA metabolites remains obscure. We therefore evaluated the pharmacokinetics of three AZA metabolites: 6-mercaptopurine (6-MP), the immediate metabolite; 6-thio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a11ce4789a0443c68451b45f07cde56
https://doi.org/10.1002/j.1552-4604.1990.tb03606.x
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9
[Untitled]
Autor: P. Kucera, Daniel M. Canafax, Gary R. Erdmann, Steven K. Juhn, G. H. Jossart, G S Giebink, D. G. Levitt, Chap T. Le
Publikováno v: Pharmaceutical Research. :1242-1247
Bacteria are an important cause of acute otitis media and successful treatment depends on achieving inhibitory or bacteriacidal antimicrobial drug concentrations in the middle ear. To evaluate further otitis media treatment success and failure, we de
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::168203c0a44ff9813a4993e46f7eb297
https://doi.org/10.1023/a:1015977603224
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