Zobrazeno 1 - 10
of 1 335
pro vyhledávání: '"GARCIA, Joe G. N."'
Autor:
Tikhomirova, Victoria E., Kost, Olga A., Kryukova, Olga V., Golukhova, Elena Z., Bulaeva, Naida I., Zholbaeva, Aigerim Z., Bokeria, Leo A., Garcia, Joe G. N., Danilov, Sergei M.
Aims Angiotensin-converting enzyme (ACE), which metabolizes many peptides and plays a key role in blood pressure regulation and vascular remodeling, is expressed as a type-1 membrane glycoprotein on the surface of different cells, including endotheli
Externí odkaz:
http://hdl.handle.net/10150/625490
http://arizona.openrepository.com/arizona/handle/10150/625490
http://arizona.openrepository.com/arizona/handle/10150/625490
We have demonstrated that simvastatin and sphingosine 1-phosphate (S1P) both attenuate increased vascular permeability in preclinical models of acute respiratory distress syndrome. However, the underlying mechanisms remain unclear. As Kruppel-like fa
Externí odkaz:
http://hdl.handle.net/10150/623874
http://arizona.openrepository.com/arizona/handle/10150/623874
http://arizona.openrepository.com/arizona/handle/10150/623874
Autor:
Elangovan, Venkateswaran Ramamoorthi, Camp, Sara M., Kelly, Gabriel T., Desai, Ankit A., Adyshev, Djanybek, Sun, Xiaoguang, Black, Stephen M., Wang, Ting, Garcia, Joe G. N.
Mechanical ventilation, a lifesaving intervention for patients with acute respiratory distress syndrome (ARDS), also unfortunately contributes to excessive mechanical stress and impaired lung physiological and structural integrity. We have elsewhere
Externí odkaz:
http://hdl.handle.net/10150/622492
http://arizona.openrepository.com/arizona/handle/10150/622492
http://arizona.openrepository.com/arizona/handle/10150/622492
Expression Profiling Elucidates a Molecular Gene Signature for Pulmonary Hypertension in Sarcoidosis
Autor:
Singla, Sunit, Zhou, Tong, Javaid, Kamran, Abbasi, Taimur, Casanova, Nancy, Zhang, Wei, Ma, Shwu-Fan, Wade, Michael S., Noth, Imre, Sweiss, Nadera J., Garcia, Joe G. N., Machado, Roberto F.
Pulmonary hypertension (PH), when it complicates sarcoidosis, carries a poor prognosis, in part because it is difficult to detect early in patients with worsening respiratory symptoms. Pathogenesis of sarcoidosis occurs via incompletely characterized
Externí odkaz:
http://hdl.handle.net/10150/622494
http://arizona.openrepository.com/arizona/handle/10150/622494
http://arizona.openrepository.com/arizona/handle/10150/622494
Autor:
Indik, Julia H., Nair, Vineet, Rafikov, Ruslan, Nyotowidjojo, Iwan S., Bisla, Jaskanwal, Kansal, Mayank, Parikh, Devang S., Robinson, Melissa, Desai, Anand, Oberoi, Megha, Gupta, Akash, Abbasi, Taimur, Khalpey, Zain, Patel, Amit R., Lang, Roberto M., Dudley, Samuel C., Choi, Bum-Rak, Garcia, Joe G. N., Machado, Roberto F., Desai, Ankit A.
Sudden death is a leading cause of mortality in sickle cell disease, implicating ventricular tachyarrhythmias. Prolonged QTc on an electrocardiogram (ECG), commonly seen with myocardial ischemia, is a known risk for polymorphic ventricular tachycardi
Externí odkaz:
http://hdl.handle.net/10150/622120
http://arizona.openrepository.com/arizona/handle/10150/622120
http://arizona.openrepository.com/arizona/handle/10150/622120
Autor:
Danilov, Sergei M., Lünsdorf, Heinrich, Akinbi, Henry T., Nesterovitch, Andrew B., Epshtein, Yuliya, Letsiou, Eleftheria, Kryukova, Olga V., Piegeler, Tobias, Golukhova, Elena Z., Schwartz, David E., Dull, Randal O., Minshall, Richard D., Kost, Olga A., Garcia, Joe G. N.
Angiotensin I-converting enzyme (ACE) hydrolyzes numerous peptides and is a critical participant in blood pressure regulation and vascular remodeling. Elevated tissue ACE levels are associated with increased risk for cardiovascular and respiratory di
Externí odkaz:
http://hdl.handle.net/10150/621944
http://arizona.openrepository.com/arizona/handle/10150/621944
http://arizona.openrepository.com/arizona/handle/10150/621944
Autor:
Duarte, Julio D., Desai, Ankit A., Sysol, Justin R., Abbasi, Taimur, Patel, Amit R., Lang, Roberto M., Gupta, Akash, Garcia, Joe G. N., Gordeuk, Victor R., Machado, Roberto F.
Background Diastolic dysfunction is common in sickle cell disease (SCD), and is associated with an increased risk of mortality. However, the molecular pathogenesis underlying this development is poorly understood. The aim of this study was to identif
Externí odkaz:
http://hdl.handle.net/10150/622491
http://arizona.openrepository.com/arizona/handle/10150/622491
http://arizona.openrepository.com/arizona/handle/10150/622491
Autor:
Xie, Lishi, Chiang, Eddie T., Wu, Xiaomin, Kelly, Gabriel T., Kanteti, Prasad, Singleton, Patrick A., Camp, Sara M., Zhou, Tingting, Dudek, Steven M., Natarajan, Viswanathan, Wang, Ting, Black, Steven M., Garcia, Joe G. N., Jacobson, Jeffrey R.
Protein Kinase C (PKC) plays a significant role in thrombin-induced loss of endothelial cell (EC) barrier integrity; however, the existence of more than 10 isozymes of PKC and tissue-specific isoform expression has limited our understanding of this i
Externí odkaz:
http://hdl.handle.net/10150/621276
http://arizona.openrepository.com/arizona/handle/10150/621276
http://arizona.openrepository.com/arizona/handle/10150/621276
Autor:
Bime, Christian, Zhou, Tong, Wang, Ting, Slepian, Marvin J., Garcia, Joe G. N., Hecker, Louise
Sepsis-related multiple organ dysfunction syndrome is a leading cause of death in intensive care units. There is overwhelming evidence that oxidative stress plays a significant role in the pathogenesis of sepsis-associated multiple organ failure; how
Externí odkaz:
http://hdl.handle.net/10150/614751
http://arizona.openrepository.com/arizona/handle/10150/614751
http://arizona.openrepository.com/arizona/handle/10150/614751
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