Zobrazeno 1 - 10
of 1 020
pro vyhledávání: '"GANG FAN"'
Autor:
Yu-Ying Shi, Gang Fan, Ruirong Tan, Shan Li, Hua-Bing Sun, Rui Li, Mengni Yang, Shanshan Gao, Miao Liu, Meng-Yuan Dai
Publikováno v:
Cell Death and Disease, Vol 15, Iss 9, Pp 1-13 (2024)
Abstract The current selection of ligands for both proteins of interest (POI) and E3 ubiquitin ligase significantly restricts the scope of targeted protein degradation (TPD) technologies. This study introduces cell-penetrating peptide-induced chimera
Externí odkaz:
https://doaj.org/article/aac14e898bd84fae9a32372bac3d450d
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Senescence of skeletal muscle (SkM) has been a primary contributor to senior weakness and disability in recent years. The gradually declining SkM function associated with senescence has recently been connected to an imbalance between damage
Externí odkaz:
https://doaj.org/article/f497b6263b3d41ea86f3f035dbb6865f
Autor:
Shuhui Ouyang, Sunmin Xiang, Xin Wang, Xin Yang, Xuan Liu, Meilin Zhang, Yiting Zhou, Yang Xiao, Lingzhi Zhou, Gang Fan, Jing Yang
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Lipotoxicity is a well-established phenomenon that could exacerbate damage to islet β-cells and play a significant role in the development of type 2 diabetes, the underlying mechanisms of which, however, remain unclear. In lipotoxic conditi
Externí odkaz:
https://doaj.org/article/6169d3ad396f4c57a409aa9bf79e7377
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Incretin receptor agonists (IRAs), primarily composed of glucagon-like peptide-1 receptor agonists (GLP-1RAs) and glucose-dependent insulinotropic polypeptide receptor agonists (GIPRAs), work by mimicking the actions of the endogenous incretin hormon
Externí odkaz:
https://doaj.org/article/6d8f4085a1c044d280d3f618a7ffc53b
Autor:
Gang Fan, Nathan Corbin, Minju Chung, Thomas M. Gill, Evan B. Moore, Amruta A. Karbelkar, Ariel L. Furst
Publikováno v:
JACS Au, Vol 4, Iss 4, Pp 1413-1421 (2024)
Externí odkaz:
https://doaj.org/article/0e1aca9e0ebf4feaa9adb9c8b79c43cb
Autor:
Yue Liu, Qingsong Huang, Zhenhua Zhuang, Hongjing Yang, Xiaoling Gou, Tong Xu, Ke Liu, Jun Wang, Bo Liu, Peiyang Gao, Feng Cao, Bin Yang, Chuantao Zhang, Mei Chen, Gang Fan
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 7 (2024)
ABSTRACT Chronic obstructive pulmonary disease (COPD) is one of the primary causes of mortality and morbidity worldwide. The gut microbiome, particularly the bacteriome, has been demonstrated to contribute to the progression of COPD. However, the inf
Externí odkaz:
https://doaj.org/article/41565744b53c4ce7b08273c2f3142750
Publikováno v:
IEEE Access, Vol 12, Pp 83911-83924 (2024)
In this study, a backstepping sliding mode control method (NDO-ABSC) based on nonlinear disturbance observer (NDO) and adaptive line-of-sight guidance (ALOS) is proposed to address the three-dimensional path following control problem of underactuated
Externí odkaz:
https://doaj.org/article/6e079405f5ea43b9a935d493b6ae8692
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract Endovascular therapy (EVT) is effective in the treatment of large vascular occlusive stroke. However, many factors are associated with the outcomes of acute ischemic stroke (AIS) after EVT. This study aimed to identify the main factors relat
Externí odkaz:
https://doaj.org/article/857bea78f41948b481c8f577e7d1f7d3
Autor:
Zhengli Yang, Heng Lu, Zhijie Zhang, Chao Liu, Ruihua Nie, Wanchang Zhang, Gang Fan, Chen Chen, Lei Ma, Xiaoai Dai, Min Zhang, Donghui Zhang
Publikováno v:
International Journal of Digital Earth, Vol 16, Iss 1, Pp 2374-2402 (2023)
In recent years, RS and GIS technologies have played an increasingly important role in various aspects of rainfall induced landslide research. In order to systematically understand their application situation, this paper extensively used various visu
Externí odkaz:
https://doaj.org/article/e63de1928a92446ea14c14564054f07a
Autor:
Yiwen Tao, Fang Peng, Lijie Wang, Jiayi Sun, Yin Ding, Shuangfeng Xiong, Ugen Tenzin, MiMa, Tsedien Nhamdriel, Gang Fan
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: Ji-Ni-De-Xie (JNDX) is a traditional herbal preparation in China. It is widely used to treat type 2 diabetes mellitus (T2DM) in traditional Tibetan medicine system. However, its antidiabetic mechanisms have not been elucidated. The aim
Externí odkaz:
https://doaj.org/article/8ffcab7aca244a0e96553fb0647a1d43